| Yogic Neuro Therapy Limited | Health & social care | 2004 |
| Yonescat Ltd | Information & communication | 2004 |
| Yorkcourt Investments LLP | | 2018 |
| Younespro Limited | Real estate | 2021 |
| Youngblood Limited | Wholesale & retail | 2024 |
| Younify Tech Limited | Information & communication | 2024 |
| Your Beauty and Health Limited | Wholesale & retail | 2017 |
| Your Better Garden Ltd | Administrative & support | 2016 |
| Your Bills Paid Limited | Professional & scientific | 2019 |
| Your Pharma Limited | Wholesale & retail | 2026 |
| YOUR999 Limited | Information & communication | 2015 |
| YPG Motor Limited | Wholesale & retail | 2025 |
| YSL Limited | Health & social care | 2015 |
| YTY Commercial Properties Ltd | Real estate | 2025 |
| Yumchi Original Ltd | Real estate | 2022 |
| Yurugostudios Limited | Professional & scientific | 2026 |
| Z Hussain Translations Services Ltd | Professional & scientific | 2023 |
| Z& F Fast Food Service Ltd | Hospitality | 2015 |
| Zahid & YN Ltd | Construction | 2025 |
| ZAI Commerce Ltd | Wholesale & retail | 2025 |
| ZAID2017 Limited | Real estate | 2025 |
| Zaila Ltd | Construction | 2022 |
| Zainab AH Limited | Health & social care | 2026 |
| ZAK ADVISOR1 UK Limited | Real estate | 2023 |
| ZAK ADVISOR2 UK Limited | Real estate | 2024 |
| ZAK Advisors Ltd | Real estate | 2020 |
| Zakaria Transport Ltd | Transport & logistics | 2024 |
| Zane Games Ltd | Extraterritorial | 2016 |
| Zara Travel Limited | Administrative & support | 2018 |
| Zaranek's Construction Ltd | Construction | 2022 |
| Zarkles Limited | Wholesale & retail | 2019 |
| Zaynabs Coffee Limited | Hospitality | 2024 |
| Zayoona U.K. Ltd | Hospitality | 2024 |
| ZCA 16 Ltd | Health & social care | 2026 |
| Zeap Limited | Manufacturing | 2017 |
| Zebra Renewables Ltd | Wholesale & retail | 2019 |
| Zeeshan Builders & Decorators Limited | Construction | 2017 |
| Zephyr Doors Limited | Wholesale & retail | 2023 |
| Zerexify Ltd | Information & communication | 2025 |
| Zero Pest Ltd | Administrative & support | 2025 |
| Zerroud Ltd | Wholesale & retail | 2021 |
| Zesteel London Ltd | Construction | 2023 |
| Zezenia Limited | Financial services | 2024 |
| ZHA Inspire Ltd | Administrative & support | 2025 |
| ZM Skips Ltd | Water & waste | 2022 |
| ZM-688-688 Limited | Real estate | 2026 |
| Znstransfer Ltd | Transport & logistics | 2025 |
| Zones Eight Ltd | Wholesale & retail | 2022 |
| Zoomzone Ltd | Wholesale & retail | 2024 |
| Zoor Ltd | Wholesale & retail | 2025 |
| ZOT Limited | Administrative & support | 2017 |
| Zulu Construction Ltd | Construction | 2024 |
| Zuraiki and Company Limited | Extraterritorial | 2013 |
| ZUZ Building Construction Ltd | Construction | 2023 |
| Zyphren Ltd | Information & communication | 2025 |
| Zyrality Ltd | Professional & scientific | 2025 |
| ZZ & Kenzo Limited | Other services | 2022 |