| Sourced by Shen Ltd | Wholesale & retail | 2020 |
| South Coast Timber Sheds Ltd | Wholesale & retail | 2021 |
| South Hill AVE Ltd | Real estate | 2019 |
| Southall Restaurants London Ltd | Hospitality | 2015 |
| Southern Aqua Limited | Transport & logistics | 2019 |
| Southern Waste Management Ltd. | Water & waste | 2022 |
| Southgate Bath UK Limited | Wholesale & retail | 2014 |
| Sovereign Estates Management Limited | Construction | 2022 |
| Soyelle Candles Ltd | Manufacturing | 2020 |
| SP Design Construction Limited | Construction | 2019 |
| SP Kavina Ltd | Real estate | 2021 |
| SP Market Solutions Ltd | Administrative & support | 2012 |
| SP Software Limited | Information & communication | 2017 |
| Space Concepts Limited | Construction | 2017 |
| Space One Ltd | Manufacturing | 2017 |
| Spacio (London) Ltd | Wholesale & retail | 2019 |
| Spark Business Solutions Limited | Information & communication | 2021 |
| Sparkav Limited | Wholesale & retail | 2026 |
| Sparkly Service Ltd | Construction | 2023 |
| Sparrow Design & Build Limited | Construction | 2018 |
| Spartans YFC Limited | Education | 2021 |
| Spbrm Consulting Ltd | Information & communication | 2022 |
| Special Empire Limited | Other services | 2017 |
| Specsparks KP Ltd | Construction | 2021 |
| Spectrum AI Solutions Ltd | Information & communication | 2026 |
| Spectrum Rebate Ltd | Wholesale & retail | 2023 |
| Spectrum Tech Ltd | Information & communication | 2014 |
| Speed Autos Limited | Wholesale & retail | 2021 |
| Sphena Limited | Information & communication | 2026 |
| Spice Ginger Limited | Hospitality | 2025 |
| Spine & Joint Centres Limited | Health & social care | 2016 |
| Spinite Ltd | Information & communication | 2019 |
| Spirito Italiano Limited | Administrative & support | 2003 |
| Split Access Ltd | Construction | 2026 |
| SPM Chauffeurs Ltd | Transport & logistics | 2018 |
| Spoke the App Ltd | Information & communication | 2021 |
| Spotlight IQ Limited | Professional & scientific | 2025 |
| Sprak Ltd | Wholesale & retail | 2022 |
| Sprigs Vietnamese Ltd | Hospitality | 2018 |
| Spring Close Services Ltd | Wholesale & retail | 2022 |
| Square & Compass Properties Limited | Real estate | 2019 |
| SR22 Ltd | Real estate | 2025 |
| SRS Property Management Limited | Real estate | 2017 |
| SRS Trading Services Ltd | Wholesale & retail | 2019 |
| Srstradewise Ltd | Wholesale & retail | 2025 |
| SS UK Services Ltd | Construction | 2018 |
| SS5 Ltd | Wholesale & retail | 2026 |
| Ssdh Limited | Professional & scientific | 2025 |
| Sshakti Limited | Administrative & support | 2009 |
| SSM Solution Ltd | Information & communication | 2026 |
| Ssmp Real Estate Ltd | Real estate | 2023 |
| Sspecnaz Ltd | Construction | 2020 |
| Sspr Ltd | Administrative & support | 2018 |
| Ssquare Properties Ltd | Real estate | 2021 |
| Ssru Ltd | Real estate | 2024 |
| SSV London Properties Ltd | Real estate | 2023 |
| ST Stephens Realty Limited | Real estate | 2024 |
| ST. Mark Developments Limited | Construction | 2004 |
| Stabani Ltd | Information & communication | 2016 |
| Stackdate Limited | Real estate | 1989 |
| Staff for Construction Limited | Construction | 2022 |
| Stage Art Dance Ltd | Arts & recreation | 2020 |
| Stamford Brook Developments Limited | Construction | 2024 |
| Stan Design & Build Ltd | Construction | 2014 |
| Stan Plumbing & Heating Limited | Construction | 2015 |
| Standwithus UK | Education | 2012 |
| STANLEY94 Limited | Real estate | 2021 |
| Star Angel Limited | Real estate | 2023 |
| Star Contractors UK Limited | Construction | 1998 |
| Star Dynamics Ltd | Wholesale & retail | 2024 |
| Star Homecare Services Limited | Health & social care | 2017 |
| Star Plus Estate Agents and Property Management UK Limited | Real estate | 2021 |
| Star Tours Limited | Administrative & support | 1997 |
| Star Tours Properties Limited | Real estate | 2024 |
| Star Tours Transport Ltd | Administrative & support | 2019 |
| Starcrest Developments Limited | Real estate | 1990 |
| Starr Build Ltd | Construction | 2019 |
| Stars Proinvest Limited | Real estate | 2015 |
| Steel Falcon Ltd | Administrative & support | 2023 |
| Steel PAN Agency Ltd | Arts & recreation | 2025 |
| Steelvolt Ltd | Construction | 2026 |
| Steliana Stone Ltd | Manufacturing | 2024 |
| Stellar Healthcare Solutions Limited | Health & social care | 2018 |
| Stellar Managing Services Ltd | Real estate | 2021 |
| Stellar Serviced Apartments Ltd | Real estate | 2024 |
| Steph Services Ltd | Other services | 2023 |
| Sterling Major Projects Limited | Real estate | 2020 |
| Stern Advisory Global Limited | Administrative & support | 2011 |
| Stern Advisory Services Limited | Administrative & support | 2022 |
| Stern Corporate Limited | Administrative & support | 2011 |
| Stern Data Limited | Administrative & support | 2011 |
| Stewkley Properties Ltd | Real estate | 2015 |
| Stollwells Cleaning Services Limited | Administrative & support | 2021 |
| Stone Edge Kitchens Ltd | Manufacturing | 2025 |
| Stone Grinders Ltd | Manufacturing | 2020 |
| Stonehenge Construction Limited | Construction | 2021 |
| STR Business Ltd. | Professional & scientific | 2020 |
| STR Business Solutions Ltd. | Professional & scientific | 2014 |
| STR Estates Limited | Real estate | 2011 |
| STR Financial Services Ltd | Professional & scientific | 2016 |