| Safe Property and Asset Management London Limited | Real estate | 2020 |
| Safe Spark Services Ltd | Construction | 2025 |
| Safe&Store Ltd | Transport & logistics | 2022 |
| Safebrite Limited | Wholesale & retail | 2012 |
| Safeen Beds Ltd | Manufacturing | 2025 |
| Safemishra LLP | | 2020 |
| Safer Guarding Ltd | Administrative & support | 2021 |
| Safeway Express Ltd | Wholesale & retail | 2013 |
| Safeword Ltd | Information & communication | 2025 |
| Safi’S Takeaway Limited | Hospitality | 2023 |
| SAG Carpentry Ltd | Manufacturing | 2026 |
| Sage Overseas Aircouriers and Logistics Limited | Transport & logistics | 2025 |
| Sagie Limited | Real estate | 2019 |
| Sahaj Laundry Services Ltd | Other services | 2022 |
| Sahara Solutions Limited | Information & communication | 2010 |
| Sahibi Care Services Ltd | Health & social care | 2025 |
| SAI Easwary Estates LLP | | 2026 |
| SAI Enterprise Limited | Wholesale & retail | 2002 |
| Saian Gems Limited | Wholesale & retail | 2017 |
| Saint Lawrence Ltd | Wholesale & retail | 2022 |
| Sairam Retail Ltd | Other services | 2018 |
| Saiva Foods Limited | Hospitality | 2020 |
| Saiya Aesthetics Ltd | Other services | 2025 |
| SAJ Station Limited | Hospitality | 2022 |
| Saki Snacks (Midlands) Limited | Wholesale & retail | 2008 |
| Saki Snacks Limited | Wholesale & retail | 2008 |
| Sakura Communications London Limited | Professional & scientific | 2026 |
| Sakura Global Ltd | Wholesale & retail | 2025 |
| SAL Adams Property Ltd | Real estate | 2022 |
| Salfreed (Holdings) Limited | Other services | 2014 |
| Salfreed Properties Limited | Real estate | 2014 |
| Salsa 4 FUN Limited | Arts & recreation | 2011 |
| Saltonjam Ltd | Manufacturing | 2024 |
| Salvation Care Ltd | Administrative & support | 2012 |
| Salvuss Technologies Ltd | Information & communication | 2026 |
| Sama Arts Network Ltd | Information & communication | 2025 |
| Samara Global UK Limited | Wholesale & retail | 2025 |
| Samara Private Limited | Administrative & support | 2024 |
| Same Housing Limited | Real estate | 2024 |
| Same RPS Limited | Professional & scientific | 2021 |
| Sami & Co Accountants Limited | Professional & scientific | 2007 |
| Sami Capital Limited | Real estate | 2023 |
| Samitari Ltd | Real estate | 2017 |
| Samutech Limited | Information & communication | 2025 |
| Sandhill Park Limited | Real estate | 1991 |
| Sandhu Hospitality Limited | Hospitality | 2023 |
| Sandishree International Limited | Wholesale & retail | 1994 |
| Sankalp Residency Limited | Real estate | 2024 |
| Santal-Atelier Ltd | Wholesale & retail | 2026 |
| Santana Janitorial Limited | Wholesale & retail | 2023 |
| Sapphira Media & Services Ltd | Wholesale & retail | 2020 |
| SAR VEN Limited | Wholesale & retail | 2025 |
| Sarai Group Ltd | Real estate | 2026 |
| Sari Fish Bar Ltd | Hospitality | 2019 |
| Sauceberry Ltd | Arts & recreation | 2025 |
| Savannah Foods Ltd | Wholesale & retail | 2018 |
| Saveondeals Ltd. | Wholesale & retail | 2019 |
| Savers Distributors Limited | Wholesale & retail | 2015 |
| Savi Nails Ltd | Administrative & support | 2018 |
| Savoir for Information Technology Limited | Wholesale & retail | 2024 |
| Savraj International Ltd | Wholesale & retail | 2023 |
| SBA Taxi Rentals Ltd | Administrative & support | 2023 |
| SBG Brickwork Ltd | Other services | 2021 |
| Scalehall Limited | Professional & scientific | 2006 |
| Scenewerks Limited | Manufacturing | 2024 |
| Schooldisco.Com Limited | Professional & scientific | 2000 |
| Scientialex Ltd | Hospitality | 2011 |
| Scorpios 34 Limited | Real estate | 2015 |
| Screen Coatings Limited | Manufacturing | 1989 |
| Screenless Playtime Ltd | Wholesale & retail | 2026 |
| SD Jems & Sons Ltd | Wholesale & retail | 2026 |
| SDL London Limited | Administrative & support | 2019 |
| Sea, Air & Land Forwarding Limited | Transport & logistics | 1987 |
| Season 53 Ltd | Wholesale & retail | 2020 |
| Season Secrets Limited | Other services | 2014 |
| Seasons of India Properties Ltd | Real estate | 2020 |
| Seb-Tech London Ltd | Construction | 2017 |
| Seby Spedition Ltd | Transport & logistics | 2024 |
| Second Shift Group Ltd | Wholesale & retail | 2026 |
| Secret Homes Ltd | Real estate | 2023 |
| Secure EYE Security Ltd | Construction | 2026 |
| Secure Space Storage Ltd | Transport & logistics | 2019 |
| Security Tailors Ltd | Administrative & support | 2021 |
| Seebee Media Ltd | Information & communication | 2018 |
| Seem 2 Build Ltd | Construction | 2025 |
| Sefa Properties Ltd | Real estate | 2019 |
| Sekhon Enterprise Limited | Information & communication | 2022 |
| Sekhri Investments Limited | Real estate | 2026 |
| Selcomuk Energy Resources Limited | Wholesale & retail | 2025 |
| Selekt Foods Limited | Manufacturing | 2018 |
| Sena Schools Trust Ltd | Education | 2024 |
| Senasam Ltd | Real estate | 2022 |
| Sentinel Security & Risk Solutions Ltd | Administrative & support | 2026 |
| Senzo-Serv Ltd | Transport & logistics | 2022 |
| Sequel Squirrel Limited | Information & communication | 2015 |
| Serace Consult Ltd | Administrative & support | 2018 |
| Serendib Properties Limited | Real estate | 2025 |
| Serendib Property Investments Limited | Real estate | 2003 |
| Serene Windows Ltd | Construction | 2025 |
| Serenity Home Investments Limited | Real estate | 2025 |