| Stone of Strength Properties Ltd | Real estate | 2024 |
| Stone PUB Company Ltd | Hospitality | 2018 |
| Storyland Play Lounge Limited | Hospitality | 2026 |
| Strategy Made Simple Ltd | Professional & scientific | 2025 |
| Stratford College London Limited | Education | 2007 |
| Stratford School Limited | Education | 2006 |
| Street Work Professionals Ltd | Construction | 2019 |
| Strike Quantum Ltd | Information & communication | 2025 |
| Strong Start Kids Ltd | Health & social care | 2025 |
| Strong Tower Ministries | Other services | 2009 |
| Studio 56 - the Coffee HUT Ltd | Hospitality | 2025 |
| Studio Indigena International Ltd | Information & communication | 2023 |
| Studio Rigiani Limited | Professional & scientific | 2018 |
| Stuparu Trans Ltd | Transport & logistics | 2021 |
| Stylenbeauty Limited | Other services | 2020 |
| Stylistics Hair Design Limited | Other services | 2010 |
| SU Hair & Beauty Limited | Other services | 2022 |
| Success Gate Limited | Education | 2025 |
| Suchde Pharma Ltd | Health & social care | 2014 |
| Suga Bakery Ltd | Manufacturing | 2020 |
| Suhaim Ltd | Hospitality | 2023 |
| SULO25 Ltd | Hospitality | 2025 |
| Sultan Manor Estates Ltd | Real estate | 2025 |
| Sumaron Ltd | Construction | 2017 |
| Summermead Ltd | Construction | 2017 |
| Summit Send Mediation Ltd | Professional & scientific | 2024 |
| Sun City Bingo Limited | Arts & recreation | 2025 |
| Sun City Entertainment Limited | Arts & recreation | 2015 |
| Sun Valley Auto Sales Ltd | Wholesale & retail | 2025 |
| Sunny Inc Limited | Construction | 2014 |
| Sunny Ventures Limited | Manufacturing | 2015 |
| Sunnyday Haven Ltd | Health & social care | 2024 |
| Sunray Financial Solutions Limited | Financial services | 2006 |
| Sunrise Greeting Cards Ltd | Wholesale & retail | 2020 |
| Sunrise Ventures Limited | Information & communication | 2010 |
| Sunsell Ltd | Hospitality | 2026 |
| Sunshine Communications Limited | Hospitality | 2016 |
| Sunshine@Ofe Limited | Real estate | 2026 |
| Super Protection Ltd | Financial services | 2024 |
| Supermax Technologies Limited | Information & communication | 2012 |
| Suremaid Ltd | Administrative & support | 2021 |
| Suresoft Ltd | Real estate | 2016 |
| Surfacerevive Group Limited | Construction | 2026 |
| Surry Rail Limited | Construction | 2017 |
| Susan LAD Properties Limited | Real estate | 2025 |
| Susgab Limited | Health & social care | 2022 |
| Sushi Ogimachi Ltd | Hospitality | 2023 |
| SV Services Limited | Transport & logistics | 2018 |
| Svrz Limited | Information & communication | 2020 |
| SVS Transport Ltd | Other services | 2012 |
| SVS73 Ltd | Construction | 2017 |
| SW Legal Limited | Professional & scientific | 2025 |
| Swatek Ltd | Construction | 2015 |
| Swati Caritas Limited | Information & communication | 2012 |
| Swecet Trading Limited | Real estate | 2016 |
| Sweet Hannahs Limited | Wholesale & retail | 2022 |
| Sweetest Treasure Ltd | Wholesale & retail | 2021 |
| Sweetlea Gifts Ltd | Wholesale & retail | 2020 |
| Sweets From Heaven Retail (UK) Limited | Wholesale & retail | 1998 |
| Swift and Bold Driver Support Limited | Administrative & support | 2018 |
| Swift FOX Limited | Financial services | 2013 |
| Swift Group Services Ltd | Construction | 2024 |
| Swift Pro Hub Ltd | Health & social care | 2025 |
| Swift TOW Limited | Wholesale & retail | 2026 |
| Swish Hub Properties Ltd | Real estate | 2022 |
| Swit Investment Limited | Real estate | 2014 |
| Switch Digital Voice and Data Solutions Ltd | Information & communication | 2024 |
| Switch Drivers Ltd | Information & communication | 2022 |
| Switch Gym Ltd | Arts & recreation | 2022 |
| Switchdistro Limited | Information & communication | 2020 |
| Swojscy Limited | Wholesale & retail | 2014 |
| Sykes Homes Limited | Administrative & support | 2024 |
| Sylver Rail Limited | Manufacturing | 2016 |
| Sylvi Wellness Limited | Manufacturing | 2026 |
| Symboku FUN Limited | Information & communication | 2025 |
| Symmie Bows Ltd | Manufacturing | 2025 |
| Sync Care Limited | Information & communication | 2023 |
| Synergy Facility Management Ltd | Administrative & support | 2025 |
| Syntegy Limited | Information & communication | 2023 |
| Systemic Accounting Services Ltd | Professional & scientific | 2012 |
| Szilagyi Solutions Ltd | Construction | 2025 |
| Sztura Trans Ltd | Transport & logistics | 2024 |
| SZU Ltd | Wholesale & retail | 2025 |
| T & D Developments Ltd | Construction | 2022 |
| T & I Investments Ltd | Real estate | 2013 |
| T Beaney & SON Ltd | Administrative & support | 2022 |
| T Boggis Properties Ltd | Real estate | 2021 |
| T Munyarabvu Ltd | Health & social care | 2022 |
| T Robertson Limited | Administrative & support | 2013 |
| T&A Assets Limited | Real estate | 2024 |
| T&C Caravans Ltd | Wholesale & retail | 2024 |
| T&D Installations Ltd | Construction | 2022 |
| T&D Limbu Properties Limited | Real estate | 2025 |
| T&Dis Servis Ltd | Transport & logistics | 2020 |
| T&H Financial Solutions Limited | Wholesale & retail | 2024 |
| T&H Real Estate Ltd | Real estate | 2025 |
| T&K Ltd | Hospitality | 2024 |
| T&M Nails & Beauty Ltd | Other services | 2022 |
| T&O Contractors Ltd | Manufacturing | 2024 |
| T&P Betts Ltd | Other services | 2021 |