| Emdg Commercial Consultants Limited | Professional & scientific | 2023 |
| Emdol Ltd | Real estate | 2024 |
| Emdw Extra Ltd | Wholesale & retail | 2021 |
| Emerald & MAE Limited | Households | 2013 |
| Emergence Investment Ltd | Real estate | 2022 |
| Emergence Networks Ltd | Information & communication | 2015 |
| EMI & BEN Ltd. | Manufacturing | 2009 |
| Emilian Ltd | Transport & logistics | 2017 |
| Emilio Strategies LLP | | 2019 |
| Emily Sarah Brown Ltd | Extraterritorial | 2024 |
| Emira Logistics Ltd | Transport & logistics | 2023 |
| EML Essential Supplies Ltd | Wholesale & retail | 2020 |
| Emma Dike Company Ltd | Construction | 2013 |
| Emmalicia Real Estate Ltd | Real estate | 2025 |
| Emmegiesse 2020 Ltd | Real estate | 2020 |
| Empire Works (UK) Limited | Construction | 2014 |
| Empower Fire and Electrical Services Limited | Construction | 2025 |
| Empower Global Network Ltd | Information & communication | 2025 |
| Empowerher Global Limited | Professional & scientific | 2026 |
| Emro Food Company Ltd | Hospitality | 2018 |
| EMS (Installations) Ltd | Construction | 2000 |
| EMS Fabrications Ltd | Manufacturing | 2000 |
| EMS Food Ltd | Hospitality | 2024 |
| Emtress Healthcare Services Limited | Administrative & support | 2014 |
| Enceladus Investments Ltd | Professional & scientific | 2016 |
| Enclime Ltd | Professional & scientific | 2024 |
| Endo Healthcare Limited | Health & social care | 2016 |
| Endorsehq Limited | Information & communication | 2025 |
| Enel Consulting Ltd | Other services | 2016 |
| Energy From Waste Limited | Water & waste | 2011 |
| Engenious Capital Ltd | Professional & scientific | 2023 |
| Engineering Petroleum Services Ltd | Wholesale & retail | 2020 |
| English Subbuteo Association Limited | Arts & recreation | 2024 |
| Enikins Ltd | Other services | 2015 |
| Eniwaju-Excell (U.K) Limited | Transport & logistics | 2009 |
| Enlighten Grooming Education Ltd | Other services | 2022 |
| Ensise Ltd | Construction | 2022 |
| Enviro Specialist Solutions Ltd | Construction | 2021 |
| Environmental Health Tutors Ltd | Education | 2010 |
| Envirovision Dynamics Limited | Professional & scientific | 2019 |
| Envs Limited | Wholesale & retail | 2019 |
| Enweclear Ltd | Water & waste | 2023 |
| EO Management Consultancy Ltd | Professional & scientific | 2024 |
| EOB Construction Ltd | Construction | 2025 |
| Ephesian Christian Assembly | Other services | 2020 |
| Epicus Limited | Professional & scientific | 2024 |
| Epigensol Ltd | Information & communication | 2022 |
| Epping Hair Loss Clinic Limited | Health & social care | 2016 |
| Epsilon Edge Limited | Education | 2025 |
| Equatica Limited | Construction | 2024 |
| Equine Synthetics Ltd | Water & waste | 2013 |
| Equiptable Drylining Ltd | Construction | 2012 |
| Eric a. Parry & Co. Limited | Professional & scientific | 2002 |
| Erik D Construction Ltd | Construction | 2013 |
| Erikkima Ltd | Transport & logistics | 2026 |
| Eriman Limited | Administrative & support | 2024 |
| Eriskitchen Ltd | Hospitality | 2023 |
| Ernie Peter Panayi Ltd | Extraterritorial | 2024 |
| Ertika Limited | Transport & logistics | 2018 |
| ES Best House Ltd | Wholesale & retail | 2025 |
| Esarco Ltd | Wholesale & retail | 2025 |
| Escobar Logistics Ltd | Transport & logistics | 2018 |
| Escourier Limited | Transport & logistics | 2023 |
| Esje Limited | Information & communication | 2017 |
| ESR Wholesale Ltd | Wholesale & retail | 2023 |
| Essex Artisan Ltd | Manufacturing | 2018 |
| Essex General Solutions Ltd | Wholesale & retail | 2016 |
| Essex Hvac Limited | Construction | 2018 |
| Esskiz Promotions Limited | Professional & scientific | 2025 |
| Essr Consulting Group Ltd | Construction | 2016 |
| Esteban Trans Ltd | Transport & logistics | 2026 |
| Estella Homes Limited | Real estate | 2023 |
| Estuary Services Limited | Transport & logistics | 1988 |
| ETA Plumbing and GAS Services Ltd | Construction | 2025 |
| ETB 70 Limited | Transport & logistics | 2022 |
| Ethel Mansions Limited | Households | 1986 |
| EU Civil Engineering Ltd | Construction | 2021 |
| Eurekas Roti Limited | Extraterritorial | 2024 |
| Euro Drive Ltd | Transport & logistics | 2019 |
| Euroclean Contractors Limited | Administrative & support | 1997 |
| Eurogeni UK Ltd | Other services | 2019 |
| Eurostyle Limited | Construction | 2017 |
| Evalon Estates Limited | Real estate | 2025 |
| Evan Hurst Ltd | Professional & scientific | 2019 |
| Evans Empires Ltd | Real estate | 2023 |
| Evcontractors Ltd | Construction | 2019 |
| Evelina Aesthetics Ltd | Health & social care | 2022 |
| Events Management Services Ltd | Administrative & support | 2025 |
| Everlight Future Ltd | Hospitality | 2026 |
| Everprime Nova Limited | Wholesale & retail | 2026 |
| Everson Electrical Services Ltd | Energy | 2017 |
| Everthrive Ltd | Professional & scientific | 2023 |
| Everwake Games Ltd | Information & communication | 2017 |
| Everyday Barbers Ltd | Other services | 2018 |
| Everythingadhd Limited | Health & social care | 2025 |
| EVO Kent Roofing Ltd | Construction | 2021 |
| Evolution Drilling Ltd | Construction | 2025 |
| Evolution Tiling London Ltd | Construction | 2019 |
| Evolve Commissioning Ltd | Construction | 2016 |
| Evridge Group Ltd | Manufacturing | 2015 |