| Robin Nest Living Ltd | Real estate | 2026 |
| Robinroom Ltd | Real estate | 2024 |
| Robinson Building Services Limited | Construction | 1999 |
| Robinson Equestrian & Property Limited | Wholesale & retail | 2021 |
| Robo-Pmo Ltd | Professional & scientific | 2018 |
| Robotic Automation Limited | Manufacturing | 2008 |
| Rochford Homes Limited | Real estate | 1996 |
| Rocket Door Frames Limited | Wholesale & retail | 2021 |
| Rocket-X Ltd | Manufacturing | 2012 |
| Roditi 2015 Limited | Financial services | 2014 |
| ROG Dabbit Limited | Information & communication | 2010 |
| Rojok Ltd | Real estate | 2015 |
| Rondina LLP | | 2011 |
| Roofin RON Ltd | Construction | 2026 |
| Ropsley Heath Cafe & Farm Shop Ltd | Hospitality | 2023 |
| Rosant Ltd | Transport & logistics | 2020 |
| Rose River Limited | Real estate | 2024 |
| Rosemary 1959 Limited | Extraterritorial | 2013 |
| Rosewise Limited | Hospitality | 1985 |
| Rossetti Estates Limited | Real estate | 2020 |
| Rossfell Limited | Information & communication | 1988 |
| Rothlee LLP | | 2015 |
| Route 1 Group Limited | Manufacturing | 2004 |
| Rouwnblayr Ltd | Wholesale & retail | 2021 |
| ROW Houses Limited | Real estate | 2003 |
| Rowanstone Limited | Financial services | 1986 |
| Rowelight Ltd | Information & communication | 2024 |
| Rowland Watson Gunmakers Ltd | Wholesale & retail | 2026 |
| Rowleys Commercial Energy Assessment Limited | Professional & scientific | 2008 |
| RP Specialized Services Ltd | Professional & scientific | 2022 |
| RPJ Rentals Ltd | Real estate | 2025 |
| RQ Welch Ltd | Transport & logistics | 2021 |
| Rrsp Solutions Ltd | Real estate | 2018 |
| RRV Tech Limited | Information & communication | 2022 |
| RS Sales & Marketing Limited | Professional & scientific | 2024 |
| RSL Contracting Ltd | Agriculture & fishing | 2026 |
| RSM Installations Ltd | Construction | 2026 |
| Rsware Limited | Information & communication | 2025 |
| RT Food Technicals Ltd | Professional & scientific | 2015 |
| RTH Motor Services Ltd | Wholesale & retail | 2023 |
| Ruffside LLP | | 2017 |
| Rumead Ltd | Transport & logistics | 2020 |
| Rupert Brick LLP | | 2019 |
| Rupert King & Company Limited | Professional & scientific | 1996 |
| Rusco ELC Ltd | Manufacturing | 2020 |
| Rushmoor Consulting Limited | Manufacturing | 2008 |
| Russel Property and Developments Ltd | Construction | 2025 |
| Rustspanner Ltd | Administrative & support | 2020 |
| Rutland Consulting Ltd | Administrative & support | 2012 |
| Rvbm Investments Limited | Financial services | 2019 |
| RW Coldstore Construction Limited | Construction | 2017 |
| RY Gordon Ltd | Transport & logistics | 2021 |
| Ryanzas Limited | Wholesale & retail | 2025 |
| Ryevlo Ltd | Wholesale & retail | 2019 |
| S & F Hutton (Holdings) Limited | Financial services | 2016 |
| S & S Insulation Services Limited | Construction | 2009 |
| S B D Solutions Ltd | Professional & scientific | 2025 |
| S Hutton Limited | Manufacturing | 2002 |
| S J Crompton Limited | Construction | 2018 |
| S Martin 394 Limited | Professional & scientific | 2012 |
| S Mcmillan Electrical Ltd | Construction | 2024 |
| S&R Patel Limited | Real estate | 2009 |
| S.W Auto Aesthetics Ltd | Wholesale & retail | 2024 |
| Sabado Ltd | Wholesale & retail | 2025 |
| Sadatgafoor Limited | Health & social care | 2019 |
| Safety Schemes in Procurement (Ssip) Limited | Other services | 2016 |
| Sailalign Ltd | Wholesale & retail | 2021 |
| Salama Group Ltd | Administrative & support | 2023 |
| Salamanca Solutions Ltd | Other services | 2023 |
| Sally Hoppe LLP | | 2009 |
| Salop Mobility Limited | Health & social care | 2012 |
| Salty Estates Ltd | Hospitality | 2025 |
| SAM Auto(Uk) Ltd | Wholesale & retail | 2023 |
| SAM Rogers Electrical Ltd | Manufacturing | 2015 |
| SAM Wright Property Ltd | Extraterritorial | 2024 |
| Samarth Capital Investments Limited | Real estate | 2022 |
| Samicata Ltd | Wholesale & retail | 2022 |
| Samuel James Evans Limited | Real estate | 2023 |
| Sandersons Underwriting LLP | | 2009 |
| Sandison Automation Limited | Construction | 2019 |
| Sandwindows Ltd | Wholesale & retail | 2021 |
| Sanjay Stores Ltd | Wholesale & retail | 2025 |
| Sansdrama Ltd | Information & communication | 2020 |
| Sanuk Enterprises Limited | Wholesale & retail | 2010 |
| Sanuk Siam Limited | Professional & scientific | 2010 |
| Sarah Rose Wealth Management Ltd | Professional & scientific | 2025 |
| Sarahali Limited | Financial services | 2011 |
| Sarbel Limited | Administrative & support | 2010 |
| Sarsfield's Chocolaterie Ltd | Manufacturing | 2010 |
| SAS Building Developments Ltd | Real estate | 2025 |
| SAS Estates and Rentals Ltd | Real estate | 2026 |
| SAS Vehicle Repair and Sales Ltd | Wholesale & retail | 2021 |
| Sash Retail Ltd | Wholesale & retail | 2021 |
| Sataya Research Chemicals Limited | Wholesale & retail | 2025 |
| Sausage Dog Limited | Financial services | 2012 |
| Saveen Limited | Professional & scientific | 2009 |
| SBK Property Services Ltd | Real estate | 2022 |
| Scalford Park Hotel Ltd | Hospitality | 2018 |
| Scawfell Genetics Limited | Agriculture & fishing | 2017 |
| Scora Limited | Financial services | 2017 |