| Health and Exercise Matters Limited | Health & social care | 2017 |
| Hogan Building Projects Limited | Construction | 2019 |
| Holmrook Service Station Ltd | Wholesale & retail | 2004 |
| Horsley Properties Limited | Construction | 2001 |
| Horsley Quenet Engineering Limited | Manufacturing | 1971 |
| Horsley Quenet Machining Limited | Manufacturing | 1985 |
| Howard Russell Construction Limited | Construction | 1997 |
| ICF North East Ltd | Construction | 2019 |
| Inkus Ltd | Health & social care | 2010 |
| Insight NE Limited | Professional & scientific | 2017 |
| Interiors of Ripon Ltd | Wholesale & retail | 2024 |
| Irango Limited | Professional & scientific | 2019 |
| Irton Limited | Wholesale & retail | 1996 |
| J & J Taxis Limited | Transport & logistics | 2014 |
| J & L Madden Holdings Limited | Financial services | 2026 |
| Jams Properties (North East) Limited | Real estate | 2024 |
| JDW New Build Plumbing and Heating Ltd | Construction | 2024 |
| John Baxter & Company (Newcastle) Limited | Real estate | 1918 |
| KDM Automotive Ltd | Wholesale & retail | 2024 |
| Kestrel Conveyancing Ltd | Financial services | 2026 |
| Lagom Solutions Ltd | Information & communication | 2019 |
| LED Electrical Solutions Ltd | Construction | 2017 |
| LGA Developments Limited | Real estate | 2015 |
| Limitless Living Support Ltd | Health & social care | 2026 |
| Longstone House Holidays Limited | Real estate | 2024 |
| Luke Littler Ltd | Extraterritorial | 2024 |
| LW Digital Marketing Limited | Professional & scientific | 2025 |
| M-Technic Fabrications Limited | Administrative & support | 2009 |
| Maintenance Property Management Ltd | Administrative & support | 2016 |
| Mark Sloan Limited | Administrative & support | 2010 |
| Marra Lake District Limited | Administrative & support | 2025 |
| Marrons Plumbing and Heating Limited | Construction | 2014 |
| MAX Plastering Ltd | Construction | 2020 |
| Mclean, Riley and Thompson Seafood Specialists Ltd | Wholesale & retail | 2017 |
| Meaningful Escapes Limited | Administrative & support | 2015 |
| Melside Properties Limited | Real estate | 2014 |
| Metnor Group Limited | Professional & scientific | 2011 |
| MGI Group 2 Limited | Manufacturing | 2020 |
| Minor OPS Limited | Health & social care | 2007 |
| Mmeds Care Ltd | Health & social care | 2011 |
| Modern Living Homes NE Ltd | Construction | 2021 |
| Momentum Sports Injury Clinic Ltd | Health & social care | 2021 |
| Monomarket Limited | Wholesale & retail | 1986 |
| Morrison & Mann Ltd | Professional & scientific | 2014 |
| Mulberry Leisure Holdings Limited | Professional & scientific | 2005 |
| Mulberry Leisure Limited | Administrative & support | 1993 |
| National Business Crime Solution Limited | Administrative & support | 2014 |
| Neil Mason Telecommunications Limited | Other services | 2015 |
| Nesco Group Limited | Financial services | 2022 |
| Neurospectrum Limited | Health & social care | 2021 |
| Newcastle General Practice Services Ltd | Health & social care | 2014 |
| North East Music Co-Operative Limited | Education | 1995 |
| North East Property UK Ltd | Real estate | 2016 |
| Northern Protective Coatings Limited | Manufacturing | 1989 |
| Northumberland PUB Company Ltd | Hospitality | 2014 |
| Oakfield ML Limited | Health & social care | 2023 |
| Oliver Green Estates Limited | Real estate | 2023 |
| Olivers Building & Timber Merchants Ltd | Wholesale & retail | 2011 |
| Park View Healthcare Services Limited | Real estate | 2017 |
| PATH2PURCHASE Ltd | Wholesale & retail | 2025 |
| Paul Cunningham Packaging Consultancy Limited | Wholesale & retail | 2005 |
| Paul Stenton Butchers Limited | Wholesale & retail | 2021 |
| Peace and Loaf Limited | Hospitality | 2013 |
| Pepperwood Care Limited | Real estate | 2011 |
| Perfectly Planted Limited | Administrative & support | 2015 |
| Picktree Coachworks Limited | Transport & logistics | 1947 |
| Power the Change Ltd | Education | 2013 |
| Practical Compounds Limited | Manufacturing | 1974 |
| Precept (UK) Ltd | Professional & scientific | 2013 |
| Protean Solutions Limited | Professional & scientific | 2017 |
| Protomed Limited | Health & social care | 2007 |
| Providentia Holdings Limited | Financial services | 2025 |
| R Real Estate Limited | Real estate | 1998 |
| Ralt (SW) Ltd | Households | 2021 |
| Real Eating Company Cafes Limited | Hospitality | 2008 |
| Realisations (CMY) Limited | Construction | 1983 |
| Refurb Property Services Ltd | Construction | 2016 |
| Renegade Print Management Limited | Manufacturing | 2011 |
| Retro Classic Cars Ltd | Wholesale & retail | 2021 |
| RF3 Design Limited | Information & communication | 2012 |
| Ridley Brothers Limited | Manufacturing | 2012 |
| Rightbrain AI Ltd | Information & communication | 2023 |
| Rise Home Improvements Limited | Construction | 2020 |
| Robinson Brothers Construction Ltd | Construction | 2022 |
| Ryandale Ltd | Manufacturing | 2016 |
| S & M Traders Limited | Hospitality | 2014 |
| Salt Ventures Ltd | Professional & scientific | 2016 |
| Sevoda Limited | Administrative & support | 2019 |
| Sharewave Limited | Construction | 2001 |
| Silverhood Limited | Wholesale & retail | 2025 |
| SL3 Ltd | Real estate | 2019 |
| Sloan Business Consulting Limited | Administrative & support | 2008 |
| Smartcarbon Limited | Information & communication | 2016 |
| Sophie Murphy Services Limited | Professional & scientific | 2017 |
| Spinks the Chemists Limited | Wholesale & retail | 1952 |
| Sport 24 Limited | Professional & scientific | 2024 |
| Sport@Gosforth Limited | Extraterritorial | 2012 |
| Sports Club Newcastle Limited | Arts & recreation | 2025 |
| Sportsground and Landscape Services Limited | Other services | 1991 |
| Spree TV Limited | Wholesale & retail | 2021 |