| Dean Services Limited | Wholesale & retail | 1982 |
| Dean Valley Group Limited | Construction | 2023 |
| Dean Valley Trade Frames Limited | Wholesale & retail | 2024 |
| Deans Walk Inn Ltd | Hospitality | 2024 |
| Debams Ltd | Transport & logistics | 2023 |
| Debbie Innes Safeguarding Ltd | Health & social care | 2023 |
| Debors Merevale Road Management Company Limited(The) | Professional & scientific | 1976 |
| Debut Associates Limited | Professional & scientific | 2007 |
| Debvivi Ltd | Health & social care | 2018 |
| Deca Design Flooring Limited | Wholesale & retail | 2015 |
| Decibel Fire and Security (Holdings) Limited | Real estate | 2025 |
| Decibel Fire and Security Limited | Administrative & support | 2016 |
| Dedication Care Limited | Health & social care | 2015 |
| Dedman Contract Services Limited | Administrative & support | 2002 |
| DEE & Griffin Solicitors Limited | Professional & scientific | 2025 |
| DEE BEE Payroll & Bookeeping Services Limited | Administrative & support | 2002 |
| DEE Mountain Empire Ltd | Administrative & support | 2023 |
| Deep Filling Farm Limited | Hospitality | 2024 |
| Deep Nucleus AI Ltd | Information & communication | 2025 |
| Deepautomate AI Ltd | Information & communication | 2025 |
| Deepstrategies AI Ltd | Information & communication | 2025 |
| Deer Park Archers Limited | Other services | 2014 |
| Deerhurst Community Preservation | Other services | 2009 |
| Deerhurst Consulting Limited | Professional & scientific | 2015 |
| Deerhurst Parks Ltd | Construction | 2020 |
| Deerhurst Walton (Flood Management) Ltd | Households | 2015 |
| Deewan Store Limited | Wholesale & retail | 2021 |
| Dee’S Cleaning & Services Ltd | Administrative & support | 2026 |
| Defencecv Technologies Limited | Information & communication | 2025 |
| Defend and Protect Limited | Administrative & support | 2009 |
| Defender Defender Limited | Wholesale & retail | 2016 |
| Delair Properties Ltd | Real estate | 2022 |
| Deliciousfoodbyami Ltd | Manufacturing | 2024 |
| Deliedgecafe Ltd | Hospitality | 2024 |
| Delight Transport Limited | Wholesale & retail | 2018 |
| Delipizza Ltd | Hospitality | 2022 |
| DELM8 Limited | Information & communication | 2019 |
| Delmate Limited | Information & communication | 2019 |
| Delq Ltd | Wholesale & retail | 2024 |
| Delta 4 Electrical Ltd | Construction | 2014 |
| Delta Electrical Design Services Ltd | Professional & scientific | 2024 |
| Delta Sigma MU Limited | Professional & scientific | 2022 |
| Delta Supplies Ltd | Wholesale & retail | 2023 |
| Delta Team Consulting Limited | Information & communication | 2015 |
| Denman Financial Planning Ltd | Professional & scientific | 2012 |
| Denmark Court Management Company Limited | Households | 1981 |
| Denmark Road High School | Education | 2011 |
| Dennite Electrical Ltd | Construction | 2022 |
| Deno Rowlands Racing Ltd | Arts & recreation | 2025 |
| Dent Hub Dental LAB Limited | Health & social care | 2025 |
| Dent Hub Ltd | Health & social care | 2020 |
| Dent Hub Smiles Ltd | Health & social care | 2023 |
| Dent Hub Teaching Ltd | Real estate | 2021 |
| Dental Specialists Limited | Health & social care | 2022 |
| Dents Amazing Ltd | Wholesale & retail | 2021 |
| Denyer Holdings Ltd | Financial services | 2022 |
| Denyer Media Ltd | Professional & scientific | 2024 |
| Depureco UK Limited | Wholesale & retail | 1999 |
| Dermaco Skincare Limited | Wholesale & retail | 2009 |
| Desert Shrub Limited | Professional & scientific | 2023 |
| Deshi Rasoi Limited | Hospitality | 2026 |
| Designer Driveways Ltd | Administrative & support | 2022 |
| Designforliving Architects Limited | Professional & scientific | 2017 |
| Designignite Ltd | Professional & scientific | 2024 |
| Desoulfood Ltd | Hospitality | 2020 |
| Detour Ltd | Real estate | 2024 |
| DEV IT Solutions Limited | Information & communication | 2021 |
| Devereaux Court Management (NO 1) Limited | Households | 1991 |
| Devondeals Limited | Wholesale & retail | 2025 |
| Devoted Events Management Ltd | Administrative & support | 2022 |
| Dewetech Consulting Ltd | Information & communication | 2026 |
| Dfzs Enterprises Ltd | Wholesale & retail | 2020 |
| DG Residential Limited | Real estate | 2024 |
| Dhanvi Technologies Limited | Information & communication | 2014 |
| DHL Homes & Estates Limited | Real estate | 2012 |
| Dhyutidhara Technologies Ltd | Information & communication | 2021 |
| Diab Limited | Manufacturing | 1982 |
| Diablo Customs Limited | Hospitality | 2022 |
| Diagonal Lines Ltd | Information & communication | 2021 |
| Diamond Acquisition Limited | Real estate | 2025 |
| Diamond Caregivers Limited | Public administration | 2023 |
| Diamond Fit Ltd | Wholesale & retail | 2022 |
| Diamond Hair Products Ltd | Wholesale & retail | 2013 |
| Diamond Windows Glos Ltd | Construction | 2015 |
| Diamorph UK Limited | Financial services | 2012 |
| Diaunite Limited | Information & communication | 2026 |
| Diavima Holdings Ltd | Real estate | 2026 |
| Diesel Service of Gloucester Ltd | Wholesale & retail | 2022 |
| Digi Talk Consult Ltd | Information & communication | 2023 |
| Digiextreme Ltd | Wholesale & retail | 2022 |
| Diginet Limited | Information & communication | 1993 |
| Digiopia Limited | Information & communication | 2012 |
| Digital and Training Services Ltd. | Education | 2016 |
| Digital Audio Consultancy Services Limited | Administrative & support | 2020 |
| Digital Bones Ltd | Information & communication | 2024 |
| Digital Creators Guild Ltd | Health & social care | 2026 |
| Digital Paws LLP | | 2023 |
| Digital Pitch Limited | Professional & scientific | 2023 |
| Digital Security Limited | Administrative & support | 2025 |
| Digital Telecom Limited | Construction | 1991 |