| Lyme Lettings & Property Management Ltd | Real estate | 2023 |
| Lynton (Holdco 2) Ltd | Financial services | 2023 |
| Lynton Showpoint (UK) Limited | Manufacturing | 1999 |
| Lynton Trailers (UK) Limited | Manufacturing | 1999 |
| M Winterbottom Limited | Agriculture & fishing | 2015 |
| M-Plast Limited | Construction | 2009 |
| M-Power Resto Limited | Wholesale & retail | 2021 |
| M60 Cleaning Supplies Limited | Wholesale & retail | 2014 |
| MAC Clean (NW) Limited | Administrative & support | 2025 |
| Macc Pubs Limited | Hospitality | 2025 |
| Macintyre Estates Ltd | Real estate | 2016 |
| MAD Build Co Ltd | Construction | 2026 |
| MAD Doctor Holdings Limited | Wholesale & retail | 2017 |
| Made Academy Limited | Other services | 2020 |
| Maelstrom Advanced Process Technologies Ltd. | Manufacturing | 1998 |
| Magic Wizard Ltd | Professional & scientific | 2026 |
| Magloc (UK) Ltd | Manufacturing | 2013 |
| Magloc IP Limited | Professional & scientific | 2014 |
| Majic Merchants Limited | Wholesale & retail | 2006 |
| Making IT Personal Limited | Wholesale & retail | 2024 |
| Manchester Dental LAB Limited | Health & social care | 2017 |
| Manchester Theatre Academy Community Interest Company | Education | 2018 |
| Mancunia Capital Limited | Other services | 2023 |
| Manifold Access Ltd | Professional & scientific | 2019 |
| Manor Bespoke Property Maintenance Ltd | Construction | 2025 |
| Marble Computing Ltd | Information & communication | 2017 |
| MARC1 Limited | Professional & scientific | 2003 |
| Marick Labels Ltd | Manufacturing | 2009 |
| Marlborough Roofing Ltd | Construction | 2019 |
| Martyn Rourke Ltd | Other services | 2014 |
| Masf Retail Ltd | Wholesale & retail | 2026 |
| Massey Basements & Construction Limited | Construction | 2023 |
| Mast Glossop Ltd | Construction | 2024 |
| Mast Property Group Ltd | Real estate | 2021 |
| MAT IT Services Limited | Information & communication | 2009 |
| MAT Jones Fruit & VEG Wholesaler Ltd | Wholesale & retail | 2013 |
| Matrix Martial Arts Ltd | Wholesale & retail | 2018 |
| Matt & DAN Ltd | Professional & scientific | 2025 |
| Maxlex Ventures Limited | Education | 2013 |
| MAZ3344 Limited | Hospitality | 2025 |
| Mazzytech Ltd | Professional & scientific | 2017 |
| MB Security Solutions Ltd | Administrative & support | 2024 |
| MBC Fire Ltd | Construction | 2014 |
| MBT Specialist Vehicle Solutions Limited | Wholesale & retail | 2021 |
| MCC Holdings (NW) Ltd | Real estate | 2019 |
| Mccallum PR Limited | Professional & scientific | 2018 |
| Mccarthy Consulting Associates Limited | Administrative & support | 2012 |
| Mcentee Holdings Ltd | Financial services | 2019 |
| MCGAZ26 Limited | Administrative & support | 2013 |
| Mchardy Housing Limited | Real estate | 2021 |
| Mcnabarbers Limited | Other services | 2022 |
| Mctherapy Ltd | Health & social care | 2025 |
| MD NDT Services (UK) Limited | Other services | 2023 |
| MEA Properties NW Ltd | Real estate | 2025 |
| Meakins Construction Ltd | Construction | 2023 |
| Medicole Ltd | Health & social care | 2020 |
| Mediterranean Steak Ltd | Hospitality | 2024 |
| Meehan's Glossop Ltd | Hospitality | 2023 |
| Megafauna Limited | Professional & scientific | 2016 |
| Meinen Chimney Sweep Services Limited | Administrative & support | 2019 |
| Memorii Ltd | Information & communication | 2025 |
| Mere Golf & Country Club Limited | Hospitality | 1983 |
| Metal Fabrication (Glossop) Ltd | Administrative & support | 2010 |
| Meteor Mortgages & Money Limited | Financial services | 2006 |
| Mews Pharma Limited | Wholesale & retail | 2023 |
| Meyvn Services Limited | Information & communication | 2019 |
| MFW Projects Ltd | Professional & scientific | 2013 |
| MG Restaurant Management Ltd | Professional & scientific | 2023 |
| MG Restaurant Operations (Glossop) Limited | Hospitality | 2025 |
| MGL Commercial Limited | Real estate | 2021 |
| MH Industry Tech Services Ltd | Professional & scientific | 2023 |
| Midavlyn Financial Limited | Financial services | 2018 |
| Mike PYE Marketing Ltd | Administrative & support | 2017 |
| Milandro’S Ltd | Hospitality | 2026 |
| Millmais Carpentry & Joinery Limited | Manufacturing | 2025 |
| Milloh Limited | Professional & scientific | 2016 |
| Minos Academy Ltd | Administrative & support | 2014 |
| Mirza Builders Ltd | Construction | 2021 |
| Mitchells Fencing Limited | Administrative & support | 2026 |
| MJ Automotive Services (New Mills) Limited | Wholesale & retail | 2022 |
| MJC Trading Ltd | Construction | 2023 |
| MLJ Buildings Limited | Real estate | 2022 |
| MLM Motors Ltd | Wholesale & retail | 2012 |
| MMP Insulation Ltd | Manufacturing | 2023 |
| Molrose Electrical Services Ltd | Construction | 2016 |
| Monkey Business Construction Ltd | Construction | 2013 |
| Moolenbrown Limited | Professional & scientific | 2015 |
| Moorfield Speciality Brushes Limited | Professional & scientific | 2003 |
| Motone Limited | Real estate | 1977 |
| Motorsport Media Ltd | Information & communication | 2016 |
| Mountain Daze Ltd | Arts & recreation | 2025 |
| Mrpeter Ltd | Professional & scientific | 2016 |
| MS UX Design Limited | Professional & scientific | 2023 |
| MSA Foams Limited | Wholesale & retail | 2005 |
| MSA Glossop Ltd | Real estate | 2022 |
| Multifuel Limited | Wholesale & retail | 2007 |
| Multiverse Solutions Limited | Professional & scientific | 2008 |
| MVS Van Hire Limited | Administrative & support | 2022 |
| MWF Heating Ltd | Manufacturing | 2015 |
| MWF Landscapes Ltd | Construction | 2015 |