| Unblock Britain Limited | Administrative & support | 2005 |
| Unblock Cumbria Limited | Water & waste | 1999 |
| Unbounded Limited | Professional & scientific | 1996 |
| Understanding ME Ltd | Education | 2024 |
| Underwood's Fish and Chips Limited | Hospitality | 2021 |
| Underwood's Property Limited | Real estate | 2023 |
| Unholy Ltd | Extraterritorial | 2022 |
| Uniche Motor Company Limited | Wholesale & retail | 2013 |
| Unigloves (UK) Limited | Manufacturing | 2000 |
| Unilet Estates Limited | Real estate | 2019 |
| Union Brothers Industrial Limited | Manufacturing | 2021 |
| Union Parade Barber Shop Ltd | Other services | 2020 |
| Unique Accountancy Ltd | Professional & scientific | 2014 |
| Unique Care Plus Ltd | Health & social care | 2019 |
| Unit Eleven Ltd | Wholesale & retail | 2023 |
| United Fruit Growers Limited | Wholesale & retail | 2015 |
| United Grower Solutions Limited | Wholesale & retail | 2017 |
| United Investment Milner Ltd | Real estate | 2020 |
| United Kingdom CMS Ltd | Hospitality | 2021 |
| United Kingdom Pro Wrestling Ltd | Arts & recreation | 2020 |
| United Steel (Shandong) Co., Ltd | Manufacturing | 2023 |
| United Vitamins UN Limited | Wholesale & retail | 2025 |
| Unity Workwear Ltd | Manufacturing | 2026 |
| Universal Resolutions Ltd | Real estate | 2021 |
| Universal Software Solution Engineer Ltd | Information & communication | 2019 |
| Unlikely Developments Ltd | Manufacturing | 2020 |
| Unlimited Trans Ltd | Transport & logistics | 2023 |
| Unravel & Unwind C.I.C. | Wholesale & retail | 2014 |
| Upper Room Limited | Real estate | 2021 |
| Upper Walmer Properties Ltd | Real estate | 2026 |
| Upservice Pro Ltd | Real estate | 2023 |
| Urban Larder Limited | Hospitality | 2016 |
| Urban Monkey Motors Ltd | Wholesale & retail | 2026 |
| Urban Numbers (Homes) Limited | Real estate | 2020 |
| Urban Numbers Limited | Wholesale & retail | 2012 |
| Urban Training UK Ltd | Education | 2022 |
| Urbandawn Property Management Limited | Households | 1987 |
| USD Investments Ltd | Construction | 2023 |
| Usma Machinery Ltd | Extraterritorial | 2016 |
| Utilities & Industrial Solutions Limited | Professional & scientific | 2008 |
| UU Packaging Co., Ltd. | Extraterritorial | 2015 |
| Uzum Brothers Limited | Wholesale & retail | 2011 |
| Uzum Properties & Management Ltd | Real estate | 2025 |
| Uzum Properties Investment Ltd | Real estate | 2025 |
| Uzum Properties Ltd | Real estate | 2014 |
| Uzum Supermarket Ltd | Wholesale & retail | 2023 |
| V Kent Minimart Ltd | Wholesale & retail | 2014 |
| V&O Property Investments Ltd | Construction | 2023 |
| V.E. White & Co. Ltd | Professional & scientific | 2006 |
| V.N Care Ltd | Health & social care | 2025 |
| V.P.Property Development Limited | Real estate | 2010 |
| V.Scott Engineering Ltd | Manufacturing | 2003 |
| VA Virtuewell Ltd | Administrative & support | 2024 |
| Vadasabi Limited | Information & communication | 2020 |
| Vaikunth Limited | Health & social care | 2010 |
| Vale Auction Centre Ltd | Wholesale & retail | 2025 |
| Vale Tree Surgeons Limited | Agriculture & fishing | 2003 |
| Valentin&Alin Ltd | Transport & logistics | 2022 |
| Valentine Plastering Ltd | Construction | 2020 |
| Valentines Express Ltd | Transport & logistics | 2020 |
| Valley Financial Services Ltd | Financial services | 2005 |
| Valley Maintenance and Building Service Ltd | Construction | 2019 |
| Valore Cash and Carry Ltd | Wholesale & retail | 2025 |
| Vamj Construction Ltd | Construction | 2019 |
| Vantage Filtration & Building Services Ltd | Construction | 2024 |
| Vantage Parts Ltd | Wholesale & retail | 2015 |
| Vape and More Ltd | Wholesale & retail | 2025 |
| Vapeodyssey Ltd | Wholesale & retail | 2019 |
| Vardo Estates Limited | Households | 2024 |
| Vast Investment Ltd | Information & communication | 2024 |
| VBH (GB) Limited | Wholesale & retail | 1982 |
| VC Security Services Limited | Administrative & support | 2006 |
| Vector Analysis Ltd | Information & communication | 2018 |
| Velantro Travel Limited | Administrative & support | 2026 |
| Velia Media Ltd | Wholesale & retail | 2025 |
| Velinamodel Ltd | Manufacturing | 2025 |
| Velo Design Limited | Professional & scientific | 2011 |
| Velovay Ltd | Construction | 2018 |
| Vending 37 Ltd | Wholesale & retail | 2022 |
| Vending Machines Vendor Ltd | Hospitality | 2023 |
| Venn House Management Company Ltd | Households | 2023 |
| Venn Setchell Limited | Wholesale & retail | 2012 |
| Venture Coaching Ltd | Administrative & support | 2012 |
| Veotec Group Limited | Professional & scientific | 2016 |
| Veotec Holdings Limited | Manufacturing | 2016 |
| Veotec Limited | Manufacturing | 2006 |
| Veritas Fidelis Limited | Professional & scientific | 2026 |
| Verity RAE Martin Limited | Arts & recreation | 2013 |
| Vertesc Ltd | Manufacturing | 2025 |
| Vesta Pubs Limited | Hospitality | 2023 |
| VET in Touch Limited | Professional & scientific | 2017 |
| Veter Sales Ltd | Wholesale & retail | 2024 |
| Veto Property Solutions Ltd | Construction | 2026 |
| Veto Visuals Ltd | Other services | 2018 |
| Vexc HOW Design Ltd | Professional & scientific | 2019 |
| Vextory Limited | Wholesale & retail | 2026 |
| Vibracon Ltd | Professional & scientific | 2019 |
| Vibrant Vitamins & Nutritionals, Ltd | Wholesale & retail | 2022 |
| Vicdami Procurement Ltd | Administrative & support | 2013 |
| Vicmargconsults Ltd | Information & communication | 2023 |