| Staal Creations Limited | Administrative & support | 2013 |
| Stabilis Developments Ltd | Financial services | 2025 |
| Staff Made Easy Limited | Administrative & support | 2025 |
| Stags END (Hertfordshire) Limited | Other services | 2024 |
| Staindrop Hold Co Ltd | Real estate | 2024 |
| Stampwell Advisory Ltd | Professional & scientific | 2018 |
| Starmount Contracts Management Ltd | Professional & scientific | 1995 |
| Starwar Rights Limited | Information & communication | 2026 |
| Stately FX Limited | Information & communication | 2022 |
| Station Court (Bourne END) Limited | Real estate | 2021 |
| Staunch Solutions Limited | Information & communication | 2015 |
| Stayprivate Ltd | Information & communication | 2014 |
| STC BIM Services Limited | Professional & scientific | 2025 |
| Steed Fitzjohns Consulting Limited | Professional & scientific | 2007 |
| Steel Madness Ltd | Construction | 2014 |
| Stellar Global Holdings Ltd | Professional & scientific | 2022 |
| Stellar Global Ltd | Professional & scientific | 2019 |
| Stemgagement Consulting Limited | Professional & scientific | 2018 |
| Stephen Henry Mckenna Limited | Extraterritorial | 2024 |
| Stephen Mckenna Limited | Extraterritorial | 2024 |
| Stephen Prokopiou Consulting Limited | Information & communication | 2026 |
| Stephen Wells Limited | Professional & scientific | 2001 |
| Sterling and Stone Limited | Wholesale & retail | 2024 |
| Steve Peat Syndicate Limited | Arts & recreation | 2010 |
| Stoke Computer & Network Installations Limited | Information & communication | 2024 |
| Stonebridge Associates Ltd | Real estate | 2025 |
| Stoneman Holdings Limited | Professional & scientific | 2003 |
| Stoneman Management Consulting Limited | Information & communication | 2003 |
| Straffan Limited | Administrative & support | 2021 |
| Straker Deli Limited | Hospitality | 2023 |
| Straker Restaurants Limited | Hospitality | 2019 |
| Strapco Investments Limited | Real estate | 2019 |
| Strapco Ltd | Information & communication | 2016 |
| Strategically Ltd | Professional & scientific | 2026 |
| Strategy Partners International Limited | Information & communication | 1996 |
| Stratford Property Management Limited | Households | 1990 |
| Stratton Limited | Professional & scientific | 2002 |
| Strawberry Hill Management Company Limited | Households | 2017 |
| Strengthen Your Potential Ltd | Professional & scientific | 2025 |
| STRIDE4 Consulting & Training Ltd | Professional & scientific | 2015 |
| Stuart Slater Consulting Limited | Financial services | 2018 |
| Stud LS Ltd | Agriculture & fishing | 2023 |
| Studio 52 Arts Production Ltd | Information & communication | 2022 |
| Studio Augusto Limited | Professional & scientific | 2022 |
| Studio Nineteen Ltd | Administrative & support | 2022 |
| Study Hungary Limited | Education | 2014 |
| Stuffel Ltd | Wholesale & retail | 2016 |
| Substanspice Ltd | Wholesale & retail | 2019 |
| Sueno Boutique Limited | Wholesale & retail | 2020 |
| Suhana Investments Limited | Real estate | 2017 |
| Sukhi Construction Limited | Construction | 2010 |
| Sukzaza Ltd | Real estate | 2025 |
| Sun Family Investments Ltd | Real estate | 2024 |
| Sun Software & Data Solutions Limited | Information & communication | 2021 |
| Sundream Films Limited | Information & communication | 2022 |
| Sunny's Buses | Extraterritorial | 2009 |
| Sunset Pictures Limited | Other services | 2013 |
| Super Corporation Limited | Information & communication | 2015 |
| Super EST8 Ltd | Financial services | 2026 |
| Super SEO Webdesign Ltd | Information & communication | 2022 |
| Supercare Holdings Ltd | Health & social care | 2020 |
| Supercare Residential Ltd | Health & social care | 2020 |
| Superfront Ltd | Information & communication | 2025 |
| Superstar Branding Coach Ltd | Health & social care | 2021 |
| Supported Spaces Limited | Health & social care | 2023 |
| Supportive Living Group Ltd | Health & social care | 2026 |
| Surreal Medicare Limited | Wholesale & retail | 2010 |
| Suryasoftware & Data Solutions Ltd | Information & communication | 2025 |
| Sutlej Developments UK Ltd | Real estate | 2025 |
| Suturama Limited | Information & communication | 2023 |
| Suvenxcel & Co Ltd | Professional & scientific | 2019 |
| SVS Solicitors Limited | Professional & scientific | 2012 |
| Swan Investment Group Limited | Wholesale & retail | 2021 |
| Sweet Vision Ltd | Wholesale & retail | 2023 |
| Swiss Cottage Care Home Limited | Health & social care | 2022 |
| Swiss Investment Ltd | Construction | 2010 |
| Sycamore Building Company Ltd. | Construction | 1994 |
| Sycamore Homes Group Ltd | Construction | 2020 |
| Syco Systems Limited | Extraterritorial | 1988 |
| Sylvanus House Ltd | Real estate | 2021 |
| Sylvanus House Sunningdale Ltd | Real estate | 2025 |
| Symbiosis Housing Limited | Real estate | 2021 |
| Symbiosis Property Development Limited | Real estate | 2023 |
| Symulate Limited | Information & communication | 2025 |
| Sync Media Ltd | Information & communication | 2022 |
| Synergy Media Limited | Manufacturing | 2003 |
| Synessence Ltd | Professional & scientific | 2024 |
| T J Marron Property Ltd | Real estate | 2024 |
| T M Plant Ltd | Wholesale & retail | 2016 |
| T&S Estates Limited | Real estate | 2008 |
| T.Elston Electrical Ltd | Construction | 2021 |
| Talent for Care Ltd | Administrative & support | 2019 |
| Talking Spaces LLP | | 2018 |
| Tallented Ltd | Professional & scientific | 2024 |
| Tally HO Holdings Limited | Professional & scientific | 2008 |
| Tally HO PUB Co Limited | Hospitality | 2010 |
| Tanfield UK Ltd | Health & social care | 2024 |
| Tangerine Music & Talent Limited | Administrative & support | 2025 |
| Tappo PAY Ltd | Information & communication | 2018 |
| Tario Consulting Limited | Professional & scientific | 2020 |