| EEL PIE Records Limited | Wholesale & retail | 2017 |
| Einstein Admin Ltd | Administrative & support | 2024 |
| Einstein Afterlife Ltd | Other services | 2023 |
| Einstein Centurion Ltd | Professional & scientific | 2021 |
| Einstein Money Ltd | Financial services | 2017 |
| Einstein Tax Ltd | Professional & scientific | 2015 |
| EJD Enterprises Ltd | Professional & scientific | 2015 |
| Ekba Ltd | Real estate | 2024 |
| Elcob Films Limited | Information & communication | 2026 |
| Electi Finance Limited | Financial services | 2020 |
| Electi Mortgages Limited | Financial services | 2022 |
| Elevate Ballet Merchandise Ltd | Wholesale & retail | 2026 |
| Elevate Ballet School Ltd | Education | 2026 |
| Elgon Chemists Limited | Wholesale & retail | 1988 |
| Elhaam Official Ltd | Wholesale & retail | 2022 |
| Elite London Investments Ltd | Real estate | 2018 |
| Elite Performance Coaching Limited | Professional & scientific | 2007 |
| Elite Transport Logistics Ltd | Transport & logistics | 2022 |
| Ellemby Limited | Administrative & support | 2003 |
| Ellerhome Limited | Construction | 2019 |
| Ellis & Farah Limited | Information & communication | 2016 |
| Elmik Ltd | Wholesale & retail | 2024 |
| Elmknot Limited | Professional & scientific | 2018 |
| Elmsway Lifeplan Ltd | Professional & scientific | 2015 |
| Elodean Buyer Ltd | Real estate | 2019 |
| Elodean Manufacturing Ltd | Financial services | 2019 |
| Elsie Music Limited | Administrative & support | 2015 |
| Elusive Camel Holdings Ltd | Professional & scientific | 2024 |
| Elusive Camel Ltd | Professional & scientific | 1993 |
| Elvie Verse Limited | Wholesale & retail | 2025 |
| EM Global Advisory Limited | Professional & scientific | 2023 |
| Embrace Brands Limited | Professional & scientific | 2006 |
| Embrace Matcha Ltd | Administrative & support | 2014 |
| Emco Residential Ltd | Real estate | 2019 |
| Emerald Frames Limited | Wholesale & retail | 2023 |
| Emerald Grips Ltd | Professional & scientific | 2018 |
| Emian Consultancy Ltd. | Information & communication | 2016 |
| Emine Clinique Ltd | Other services | 2022 |
| Emma's Rings Ltd | Manufacturing | 2025 |
| Empennage Ltd | Professional & scientific | 2018 |
| Emseade Properties Limited | Real estate | 2018 |
| Emvi Limited | Wholesale & retail | 1998 |
| EN Thai Sing Limited | Hospitality | 2022 |
| Endeavour Electrical Ltd | Construction | 2024 |
| Endgame Accounting Ltd | Professional & scientific | 2024 |
| Endorsed Academy Limited | Arts & recreation | 2018 |
| ENE Properties Limited | Construction | 2018 |
| Energy Law Solutions Limited | Mining & quarrying | 2015 |
| Energy Logic Limited | Information & communication | 2016 |
| Energy Pyrolysis Limited | Administrative & support | 2013 |
| Engaged Online Learning Ltd | Education | 2010 |
| English Automotive Services Limited | Wholesale & retail | 2007 |
| Enhance Consultancy Ltd | Administrative & support | 2008 |
| Enhanced BDM Limited | Information & communication | 2017 |
| Enigma Partners Limited | Professional & scientific | 2025 |
| Ensco 963 Limited | Extraterritorial | 2012 |
| Enterprise Melville Limited | Information & communication | 1992 |
| Envipco (UK) Limited | Financial services | 1998 |
| Epayments Systems Limited | Administrative & support | 2012 |
| EPL Logistics Limited | Transport & logistics | 2020 |
| EPP Management Ltd | Financial services | 2024 |
| Equis in Education Ltd | Information & communication | 2023 |
| Equital Limited | Information & communication | 2025 |
| Eruma Security International Limited | Construction | 2013 |
| ERW13 Limited | Professional & scientific | 2017 |
| Esaloni Systems Limited | Information & communication | 2008 |
| ESC Prime Investments Limited | Real estate | 2018 |
| Escape Hatch Studio Ltd | Professional & scientific | 2019 |
| Esher Park Investments Limited | Real estate | 2008 |
| Esports Global UK Limited | Financial services | 2021 |
| ESS Electrical Limited | Construction | 2024 |
| Essential Construction Services (E.C.S) Limited | Construction | 2013 |
| Estates CA Ltd | Real estate | 2022 |
| Esterson Associates Limited | Other services | 1993 |
| Estimus Ltd | Manufacturing | 2017 |
| ETE RF Engineering Ltd | Manufacturing | 2006 |
| Eternia Consulting Ltd | Professional & scientific | 2023 |
| EUROCODE6.ORG Ltd | Professional & scientific | 2009 |
| Eurofree Limited | Information & communication | 1999 |
| Eurolord LLP | | 2009 |
| European Personal Mouldings Limited | Manufacturing | 2006 |
| European Textile Company Limited | Hospitality | 1986 |
| Eurospeak Academy Ltd | Construction | 2019 |
| Eurospeak Build Limited | Construction | 2021 |
| Eurotraders Global Limited | Construction | 2004 |
| Evans Technical Consultancy Limited | Professional & scientific | 2012 |
| Events Enhanced Limited | Information & communication | 2022 |
| Everlast Roofing Solutions Ltd | Construction | 2026 |
| Evershield Roofing Ltd | Construction | 2023 |
| Everymind Limited | Administrative & support | 2003 |
| EVO Workshop Ltd | Wholesale & retail | 2011 |
| Evolute Investments 1 Ltd | Financial services | 2025 |
| Excelencia Facilities Management Services Ltd | Administrative & support | 2020 |
| Excellent DRY Cleanerz Ltd | Other services | 2026 |
| Excelsior Marquees Ltd | Administrative & support | 2012 |
| Exclusitaly Limited | Wholesale & retail | 2013 |
| Exelot UK Ltd. | Transport & logistics | 2020 |
| Expedition in Whisky Limited | Wholesale & retail | 2023 |
| Experience Engineers Ltd | Professional & scientific | 2011 |
| Express Handling Services Limited | Transport & logistics | 1997 |