| Centre for Partnership LLP | | 2007 |
| Centre Front Studio Ltd | Professional & scientific | 2014 |
| Centrefinance Limited | Financial services | 2003 |
| Centron Wholesale Ltd | Wholesale & retail | 2024 |
| Ceramica Elegance Limited | Other services | 2007 |
| Cerberus Ph&S Limited | Construction | 2025 |
| Certifit Safety Ltd | Administrative & support | 2024 |
| Cestria Holdings Limited | Real estate | 2017 |
| CF Projects 20 Limited | Professional & scientific | 2020 |
| CG Groundworks (Essex) Limited | Construction | 2021 |
| CG Inspections Ltd | Construction | 2019 |
| CG North Aesthetics Ltd | Health & social care | 2018 |
| CGR Property Management & Consultancy Ltd | Real estate | 2015 |
| CH Construction (North East) Limited | Construction | 2019 |
| CH Consultancy NE Ltd | Other services | 2017 |
| Chaii Newcastle Limited | Hospitality | 2019 |
| Chalk Collective C.I.C. | Arts & recreation | 2015 |
| Chalmer Properties Ltd | Real estate | 2021 |
| Changfa CAP Holdings Limited | Professional & scientific | 2018 |
| Chani Spiro Photography Limited | Professional & scientific | 2021 |
| Channon Sports Consultancy Ltd | Administrative & support | 2021 |
| Chanoch Lenar Limited | Real estate | 2011 |
| Chantry Estates Ltd | Administrative & support | 2015 |
| Chapelhouse Stores Limited | Real estate | 1963 |
| Chard Estates Ltd | Real estate | 2024 |
| Chargemaster EV Ltd | Wholesale & retail | 2025 |
| Charis Developers and Consultants Limited | Construction | 2021 |
| Charis Investment Group Limited | Financial services | 2023 |
| Charles and Co (NE) Ltd | Other services | 2022 |
| Charlotte Charming Nails Spa Ltd | Other services | 2025 |
| Charlton Roofing North East Ltd | Construction | 2020 |
| Charlton Technical Services Limited | Construction | 2009 |
| Charnwood NE8 Ltd | Wholesale & retail | 2011 |
| Chartwise (UK) Limited | Education | 2010 |
| Chaverim GHD Ltd | Other services | 2023 |
| Chealy Services Ltd | Construction | 2015 |
| Check My Electrics Ltd | Professional & scientific | 2026 |
| Chedmere Ltd | Professional & scientific | 2022 |
| Cheerful Bargains Ltd | Wholesale & retail | 2011 |
| Chef LI Ltd | Hospitality | 2022 |
| Chefs Popular Ltd | Wholesale & retail | 2022 |
| Chemistry Marketing (North East) Limited | Professional & scientific | 2014 |
| Chennupati Trading Limited | Wholesale & retail | 2024 |
| Cherry Tree Hill Limited | Arts & recreation | 2023 |
| Cherry Tree Translations Limited | Professional & scientific | 2017 |
| CHERRYCARE360 Ltd | Information & communication | 2026 |
| Cherrypicker Shop Ltd | Wholesale & retail | 2020 |
| Cherrytree Storage Solutions Ltd | Real estate | 2024 |
| Chester LE Street Amateur Rowing Club | Arts & recreation | 2011 |
| Chester Nadon Ltd | Hospitality | 2010 |
| Chesterwest Holdings Ltd | Real estate | 2025 |
| Cheviot (NE) Development Ltd | Construction | 2019 |
| Cheviot Air Ltd | Professional & scientific | 2018 |
| Chevron Taxis Limited | Transport & logistics | 1997 |
| Chic Brushwork Ltd | Construction | 2025 |
| Chico Estates Limited | Real estate | 2024 |
| China Garden (NE) Ltd | Hospitality | 2016 |
| Chinesm Ltd | Hospitality | 2025 |
| Chip and PIN Direct (Terminals) Ltd | Administrative & support | 2012 |
| Chiropractic Wellness UK Limited | Other services | 2012 |
| Chloes Aesthetics Ltd | Other services | 2024 |
| Chocolate Moments Ltd | Wholesale & retail | 2018 |
| Choille Limited | Hospitality | 2024 |
| Chollerford GH LLP | | 2004 |
| Chop Chop Chinese Ltd | Hospitality | 2024 |
| Chop Chop Ltd | Hospitality | 2025 |
| Chowdene Consultancy Limited | Professional & scientific | 2020 |
| Chpathoo Ltd | Wholesale & retail | 2025 |
| Chris Auld Photography Limited | Professional & scientific | 2002 |
| Chris FEE Ltd | Mining & quarrying | 2026 |
| Chris Henshall Employment Solicitors (Ches) Limited | Professional & scientific | 2025 |
| Chris IAN Carss Autos Limited | Wholesale & retail | 2023 |
| Chris Shaw Entertainment Ltd | Arts & recreation | 2026 |
| Christine Harding Productions Limited | Information & communication | 2017 |
| Christop Limited | Wholesale & retail | 2025 |
| Christopher a Hill Ltd | Construction | 2017 |
| Chroma Beauty Ltd | Other services | 2024 |
| Chromel Limited | Other services | 2010 |
| Chrysalis Training Services Limited | Education | 2017 |
| Chuks Medical Services Limited | Health & social care | 2022 |
| Chuma Offor Legal Services Limited | Professional & scientific | 2023 |
| Chunks Fish & Chips Ltd | Hospitality | 2022 |
| Church Fields (New Hartley) Management Company Limited | Households | 2021 |
| Chyp Ltd | Construction | 2024 |
| Chysoprime Ltd | Administrative & support | 2025 |
| Cicerone Ltd | Other services | 2025 |
| Cida Global Limited | Professional & scientific | 2018 |
| Ciesielska Ltd | Health & social care | 2014 |
| CIL Taxis Limited | Administrative & support | 2015 |
| Cila Medical Services Ltd | Health & social care | 2021 |
| Circe Holdings Ltd | Other services | 2025 |
| Circle and Links Limited | Wholesale & retail | 2018 |
| Circus Extreme Limited | Administrative & support | 2011 |
| Circus Fantasia Limited | Arts & recreation | 2012 |
| Circus Zyair Limited | Arts & recreation | 2012 |
| Citizens Advice Gateshead | Other services | 1991 |
| Citrine House Limited | Real estate | 2025 |
| City Fresh Food Services Limited | Wholesale & retail | 2015 |
| City of Night Music Limited | Information & communication | 2021 |
| City Seeds CIC | Agriculture & fishing | 2021 |