| SRG Fabrications Ltd | Manufacturing | 2023 |
| SRK Commercial Limited | Real estate | 2020 |
| ST Catherine's Court (Frome) Limited | Households | 1989 |
| ST Michael's Court (Monkton Combe) Limited | Professional & scientific | 2006 |
| ST Michael`S House (Lyme Regis) Management Limited | Administrative & support | 2007 |
| ST. Aldhelms Court Management Company Limited | Households | 2003 |
| Standsure Developments Limited | Construction | 2006 |
| Star Naming Gifts Ltd | Wholesale & retail | 2019 |
| Station Approach Frome Ltd | Real estate | 2018 |
| Stephen Kirby Ltd | Wholesale & retail | 2003 |
| Sterk Cocktail Bar Ltd | Hospitality | 2025 |
| Sterk Kitchen Bar Limited | Hospitality | 2024 |
| Stewarts Dairy Ltd | Wholesale & retail | 2003 |
| Still Life GIN Limited | Manufacturing | 2020 |
| Stockholm Tree Pits Ltd | Wholesale & retail | 2021 |
| Stoke House BA11 Management Limited | Households | 2019 |
| Stonebridge Community Management Association (NO 1) Limited | Households | 1975 |
| Stonecutter Construction Ltd | Construction | 2015 |
| Stony Properties Management Company Limited | Real estate | 2007 |
| Stony Street Stores Ltd | Wholesale & retail | 2023 |
| Strange Mirror Studios Limited | Arts & recreation | 2017 |
| Strategy by Numbers Limited | Professional & scientific | 2026 |
| Stratton Palmer Properties Ltd | Real estate | 2021 |
| Strig Consulting Limited | Professional & scientific | 2015 |
| Strikeforce Supplies Limited | Wholesale & retail | 2011 |
| Structural Oak Ltd | Manufacturing | 2007 |
| Studio Becoming Ltd | Professional & scientific | 2021 |
| Studio KR London Ltd | Professional & scientific | 2014 |
| Studio Luma Limited | Manufacturing | 2017 |
| Studio Make Believe Ltd | Administrative & support | 2006 |
| Studio Quercus Limited | Professional & scientific | 2022 |
| Studio Tristan Ltd | Professional & scientific | 2017 |
| Sturdy Cycles Ltd | Manufacturing | 2014 |
| Sturdy Storage Ltd | Real estate | 2017 |
| Stylish Ambience Ltd | Information & communication | 2014 |
| Stylish Entertainment Ltd | Arts & recreation | 2011 |
| Suave Drinks Limited | Manufacturing | 2021 |
| Summerstead Developments Ltd | Construction | 2025 |
| Sunbird People Ltd | Administrative & support | 2024 |
| Sunflower Childcare Frome Ltd | Health & social care | 2020 |
| Sunhill Enterprises Ltd | Professional & scientific | 2014 |
| Sunlight Cleaning Limited | Administrative & support | 2017 |
| Sunny BOY Limited | Hospitality | 2025 |
| Sunrock Films Ltd | Information & communication | 2019 |
| SUNSHINE55 Ltd | Wholesale & retail | 2019 |
| Super Motivated Ltd | Education | 2025 |
| Super Roots Outdoor Kids CIC | Education | 2019 |
| Superclean Express Limited | Administrative & support | 2010 |
| Sussex Marine Consultants Ltd | Professional & scientific | 2021 |
| Sustainable Frome Community Interest Company | Other services | 2008 |
| SV Hydraulics Ltd | Administrative & support | 2024 |
| Swallows Property Limited | Real estate | 2007 |
| SWB Milk Deliveries Ltd | Wholesale & retail | 2006 |
| Sweet & Wild Ltd | Wholesale & retail | 2024 |
| Sweet BEE Holdings Limited | Financial services | 2024 |
| Sweet BEE Organics Ltd | Wholesale & retail | 2019 |
| Sweetnap Caravans Limited | Hospitality | 2016 |
| Swiftbuild Construction Limited | Construction | 2013 |
| Sylvia Johnson Limited | Professional & scientific | 2002 |
| Symonds-Moore CR Ltd | Professional & scientific | 2013 |
| Syncsmith Ltd | Information & communication | 2020 |
| Synvest Limited | Administrative & support | 2007 |
| Systems Engineering & Assessment International Ltd | Public administration | 2024 |
| SYT Network Ltd | Administrative & support | 2022 |
| Syxth Limited | Manufacturing | 2014 |
| T & I Accounting Ltd | Professional & scientific | 2024 |
| T & S Therapies Limited | Health & social care | 2025 |
| T B Edmonds Equine Sales Ltd | Administrative & support | 2018 |
| T D Haygreen Ltd | Construction | 2019 |
| T J Electrical Services (Somerset) Limited | Construction | 2013 |
| T J Truman General Builder Ltd | Construction | 2026 |
| T&A Land Associates Ltd | Construction | 2015 |
| T.O Roofing Ltd | Construction | 2022 |
| Tabb Media Limited | Information & communication | 2013 |
| Tabletop Group Ltd | Wholesale & retail | 2025 |
| Tall Trees Holdings Limited | Financial services | 2015 |
| Tall Trees Kindergarten Ltd | Education | 2006 |
| Tally HO Interactive Ltd | Information & communication | 2024 |
| TAO Sales Limited | Professional & scientific | 2026 |
| Tavistock Consultants Limited | Health & social care | 2018 |
| Taylor Brothers Builders Ltd | Construction | 2012 |
| Taylor Kendall Limited | Professional & scientific | 2011 |
| TBT Marketing Limited | Administrative & support | 2000 |
| TBT Recruitment Ltd | Administrative & support | 2013 |
| Tech Chap Media Ltd. | Information & communication | 2016 |
| Techmann Tech Ltd | Information & communication | 2026 |
| Teddy's Tails Ltd | Other services | 2025 |
| Telperion Limited | Professional & scientific | 2005 |
| Tenir Ltd | Financial services | 2021 |
| Teps Holdings Limited | Administrative & support | 2016 |
| Terraform Design Ltd | Professional & scientific | 2012 |
| Terrafricana Ltd | Wholesale & retail | 2021 |
| Terrestrial | Arts & recreation | 2017 |
| Terry Charles Wadman Ltd | Extraterritorial | 2021 |
| Terry Pomeroy Ltd | Wholesale & retail | 2003 |
| TF Construction Ltd | Construction | 2019 |
| TGW Enterprises Ltd | Administrative & support | 2017 |
| TGW Fitness Limited | Arts & recreation | 2022 |
| THE 23RD Folio Limited | Real estate | 2014 |
| THE Adorable Pooch Company Limited | Wholesale & retail | 2021 |