| Crewood END Investments Limited | Financial services | 2018 |
| Crewood Limited | Agriculture & fishing | 2019 |
| Croft Associates Search Limited | Administrative & support | 2016 |
| Crofts LEA Park Properties Limited | Real estate | 2025 |
| Croslands Holdco Ltd | Real estate | 2015 |
| Crowdr Software Ltd | Information & communication | 2018 |
| CS2 Limited | Professional & scientific | 1999 |
| Csji Ltd | Transport & logistics | 2024 |
| CSS Limited | Administrative & support | 2024 |
| CSS Telecoms Limited | Information & communication | 2020 |
| CW Adult Social Care Ltd | Health & social care | 2022 |
| CWC 360 Limited | Administrative & support | 2004 |
| CWC 361 Limited | Administrative & support | 2024 |
| CWL Entertainment Ltd | Arts & recreation | 2023 |
| D Hillier Ltd | Other services | 2022 |
| Daccus Architects & Construction Managers Limited | Professional & scientific | 2014 |
| Daccus Holdings Limited | Real estate | 2019 |
| Daliza Limited | Real estate | 2021 |
| Dandelion Gifts Limited | Wholesale & retail | 2019 |
| Dantom Properties Ltd | Real estate | 2026 |
| Dark ARC Solutions Ltd | Professional & scientific | 2023 |
| David Ford Enterprises Limited | Construction | 2011 |
| Davies Trading Ltd | Construction | 2021 |
| Dcjm Ltd | Financial services | 2025 |
| DCR Training Limited | Construction | 2007 |
| Dean Elliott Limited | Transport & logistics | 2010 |
| Delamere Cabinet Makers Limited | Manufacturing | 2011 |
| Delamere Fortune Palace Restaurant Ltd | Hospitality | 2018 |
| Design Build & Fit Ltd | Construction | 2022 |
| Design Co UK Limited | Professional & scientific | 2002 |
| Design DEN Limited | Information & communication | 2026 |
| Destroyerpoker&Clothing Ltd | Wholesale & retail | 2025 |
| Develop Capability Ltd | Professional & scientific | 2011 |
| Dietitian RO Ltd | Health & social care | 2013 |
| Dino Haircut Ltd | Other services | 2026 |
| Dippa Limited | Financial services | 2022 |
| District Taxis Ltd | Transport & logistics | 2017 |
| DJL Advisory Ltd | Professional & scientific | 2022 |
| DM Chemicals Limited | Wholesale & retail | 2004 |
| DMG Property Group Ltd | Real estate | 2023 |
| DMG Property Managementcompany Limited | Real estate | 2025 |
| Dncp Holdings Ltd | Real estate | 2025 |
| DP Investment Holdings Ltd | Financial services | 2016 |
| Drilling Supplies UK Limited | Wholesale & retail | 2007 |
| Dunham Arms Limited | Hospitality | 2016 |
| Dunham on the Hill & Hapsford Community Project Ltd | Arts & recreation | 2007 |
| Dynamic Sampling UK Limited | Construction | 2001 |
| Dynamica Engineering Ltd | Professional & scientific | 2018 |
| E Delaney TM Ltd | Construction | 2017 |
| E L Traynor Limited | Hospitality | 2025 |
| E Surety Ltd | Professional & scientific | 2020 |
| E.L-Xpert Ltd | Professional & scientific | 2019 |
| Eagle RAY Ltd | Real estate | 2026 |
| Eco Print Innovations Ltd | Manufacturing | 2024 |
| Ecofell Tree Surgery Ltd | Agriculture & fishing | 2018 |
| Edgy Advisory Limited | Professional & scientific | 2024 |
| EIB Group Limited | Professional & scientific | 2018 |
| ELA Frodsham Ltd | Hospitality | 2024 |
| Elfgon Limited | Real estate | 2013 |
| Elite Fest UK Ltd | Arts & recreation | 2026 |
| Elite Repossessions and Finance Solutions Ltd | Wholesale & retail | 2026 |
| Ella Creative Limited | Other services | 2020 |
| Ellen Thomas Bridal Limited | Wholesale & retail | 2016 |
| Ellington Green Cheshire Ltd | Real estate | 2025 |
| Ellis-Morgan Property Ltd | Real estate | 2020 |
| ELS Futures Limited | Financial services | 2015 |
| Elysium Personal Fitness Studios (Frodsham) Ltd | Other services | 2024 |
| Emerald Carbon Consultants Limited | Professional & scientific | 2022 |
| Empire Aesthetics Chester Limited | Other services | 2018 |
| Empire Aesthetics Liverpool Limited | Other services | 2018 |
| Empire Property Developments Cheshire Limited | Real estate | 2023 |
| Enchanted Forage Limited | Education | 2024 |
| Entrainment Limited | Professional & scientific | 2007 |
| Enviresearch Limited | Professional & scientific | 2001 |
| Equine QR Ltd | Wholesale & retail | 2024 |
| Erindale Estate Management Co. Limited | Households | 2021 |
| ESM Media Limited | Information & communication | 2025 |
| Essential Design (North West) Limited | Other services | 2002 |
| Euro Tree Woodfuel Limited | Agriculture & fishing | 2008 |
| Evelly Limited | Wholesale & retail | 2025 |
| Evoke People Development Limited | Administrative & support | 2012 |
| Evolutionary Mind Ltd | Education | 2025 |
| Excel Consultancy Group Ltd | Professional & scientific | 2025 |
| Exotic Lounge AHS Ltd | Hospitality | 2026 |
| Expound Design Ltd | Professional & scientific | 2020 |
| Exton Property Ltd | Real estate | 2024 |
| Extra Edge Ltd | Wholesale & retail | 2024 |
| F.B. Evans & SON Limited | Agriculture & fishing | 2012 |
| FBA Charlotte Limited | Education | 2025 |
| Fearns Pharmacy Ltd | Wholesale & retail | 2002 |
| Feathkick Ltd | Manufacturing | 2025 |
| Fern Meadows Management Company Ltd | Households | 2014 |
| Fibre Splicing UK Limited | Information & communication | 2013 |
| Fibrelight Ltd | Construction | 2022 |
| Fifes Consulting Limited | Professional & scientific | 2023 |
| Filtongate Limited | Professional & scientific | 1989 |
| Fintriz Ltd | Information & communication | 2026 |
| Fleet Hire Ltd | Administrative & support | 2024 |
| Fleetnetix Ltd | Wholesale & retail | 2021 |
| Flintshire Plumbing and Heating Limited | Construction | 2021 |