| Simran Construction Work Ltd | Construction | 2021 |
| Singh and Sons Properties Limited | Real estate | 2025 |
| Singh Fitness UK Ltd | Arts & recreation | 2020 |
| Singh Sukh Construction Limited | Construction | 2025 |
| Singularity Analytics Ltd | Information & communication | 2019 |
| Sipo Group Ltd | Information & communication | 2024 |
| Sipsa Ltd | Information & communication | 2025 |
| Siri Real Estates Limited | Real estate | 2021 |
| Sirivarma Ltd | Information & communication | 2022 |
| Sisa Exim Ltd | Wholesale & retail | 2023 |
| Sisa International PVT. Ltd. | Administrative & support | 2014 |
| Sisnbc Ltd | Construction | 2022 |
| Sithara Toursuk Ltd | Administrative & support | 2026 |
| SIV Ventures Limited | Real estate | 2018 |
| Siwa Support Solution Ltd | Administrative & support | 2020 |
| Siya&Co Ltd | Wholesale & retail | 2024 |
| SJ Mobile Accessories Ltd | Wholesale & retail | 2025 |
| SJN & Star Company Limited | Hospitality | 2026 |
| SJS Soluition Limited | Construction | 2025 |
| SK Luxury Properties Limited | Real estate | 2020 |
| SK Prestige Limited | Administrative & support | 2016 |
| SK Services and Solutions Ltd | Administrative & support | 2025 |
| SK Supplied Ltd | Wholesale & retail | 2024 |
| Skee UK Ltd | Information & communication | 2016 |
| SKF Cleaning Ltd | Administrative & support | 2023 |
| SKF Direct Ltd | Transport & logistics | 2025 |
| Skgghysekt Ltd | Manufacturing | 2026 |
| Skill Developers Ltd | Real estate | 2026 |
| Skin Care Solutions Clinic Ltd | Wholesale & retail | 2022 |
| Skinez Ltd | Manufacturing | 2021 |
| SKS Accounting Ltd | Professional & scientific | 2024 |
| SKS Trade Ltd | Wholesale & retail | 2024 |
| Skull Private Limited | Construction | 2024 |
| Sky Chauffeurs Ltd | Transport & logistics | 2023 |
| Sky Holdings (London) Limited | Real estate | 2016 |
| Sky MOT Ltd | Wholesale & retail | 2019 |
| Sky PCO Ltd | Administrative & support | 1996 |
| Sky Support Ltd | Administrative & support | 2021 |
| Sky Tyre and MOT Centre Limited | Wholesale & retail | 2024 |
| Sky Tyre and Parts Ltd | Wholesale & retail | 2014 |
| Sky UK Entertainment Ltd | Other services | 2021 |
| Sky Worldwide Courier Limited | Administrative & support | 2019 |
| Sky-Porter Air Services Limited | | 1983 |
| SKY1 Roofing Ltd | Construction | 2022 |
| Skyline Estates Agents Limited | Construction | 2024 |
| Skyrise Service Ltd | Construction | 2026 |
| Skytanking UK Ltd | Wholesale & retail | 2025 |
| Skyways Aluminum Shopfront Ltd | Construction | 2019 |
| Skyways Rise Limited | Administrative & support | 2022 |
| Skyways Transport Ltd | Transport & logistics | 2024 |
| SL Premium Cleaning Service Ltd | Administrative & support | 2026 |
| Slash DOT Tech Ltd | Other services | 2024 |
| Sleek Unique Design & Build Ltd | Construction | 2023 |
| Sleeplicity UK Limited | Hospitality | 2019 |
| Sliced Motors Ltd | Wholesale & retail | 2018 |
| Sliceit Limited | Information & communication | 2011 |
| Slizzle Ltd | Wholesale & retail | 2025 |
| SM Global Group Ltd | Administrative & support | 2018 |
| SMA Daily Fresh Ltd | Hospitality | 2026 |
| Smart Airports Limited | Professional & scientific | 2014 |
| Smart Capital Homes Limited | Real estate | 2015 |
| Smart Edge Consulting Ltd | Information & communication | 2019 |
| Smart Home Builders Ltd | Construction | 2018 |
| Smart Improvements Consultancy Ltd | Construction | 2021 |
| Smart Pro Logistics Limited | Transport & logistics | 2021 |
| Smart SET Properties Limited | Households | 2023 |
| Smartshoppersavers Limited | Other services | 2025 |
| Smartsoft Systems Ltd | Information & communication | 2022 |
| Smartway Roofing and Guttering Ltd | Construction | 2026 |
| Smartway Roofing Solutions Ltd | Construction | 2025 |
| Smash and Flip Ltd | Hospitality | 2026 |
| Smash the Beef Limited | Hospitality | 2025 |
| SMB Catering (Private) Limited | Hospitality | 2024 |
| Smha Properties Limited | Real estate | 2024 |
| SMI13 Limited | Financial services | 2011 |
| SMILE.DENT4U Ltd | Health & social care | 2024 |
| Smith & Webster E-Waste Ltd | Water & waste | 2026 |
| Smith&Co Traders Limited | Wholesale & retail | 2025 |
| Smooth Finish Masters Limited | Construction | 2025 |
| SNF Trade Ltd | Wholesale & retail | 2025 |
| SNG Construct Ltd | Manufacturing | 2023 |
| Snow Crest Consulting Ltd | Professional & scientific | 2025 |
| Snugglesoft Ltd | Wholesale & retail | 2025 |
| Sodhi & Patil Construction Ltd | Construction | 2017 |
| Soel Solutions Ltd | Wholesale & retail | 2024 |
| Soft Solutionss Ltd | Information & communication | 2024 |
| Soft Tech London Ltd | Information & communication | 2022 |
| Softcom Data Systems Limited | Information & communication | 2023 |
| Softech Solution Consultants Limited | Information & communication | 2009 |
| Software Labs Limited | Information & communication | 2023 |
| Sohaib & Co Ltd | Professional & scientific | 2018 |
| Soham SRI Services Ltd | Other services | 2025 |
| Sohi Courier Service Ltd | Transport & logistics | 2022 |
| Solar & Grid Installations Ltd | Construction | 2023 |
| Solarus Group Limited | Wholesale & retail | 2004 |
| Solid DEV Limited | Information & communication | 2011 |
| Solid Seal Glazing Solutions Ltd | Manufacturing | 2026 |
| Solidmark Construction Ltd | Construction | 2025 |
| Solstria Limited | Real estate | 2024 |
| Solute Limited | Information & communication | 2025 |