| Sahasra Food & Wine Limited | Wholesale & retail | 2023 |
| Sahej Food & Wine Ltd | Wholesale & retail | 2020 |
| Sahesa Ltd | Construction | 2023 |
| Sahran Services Ltd | Transport & logistics | 2022 |
| SAI Guru Consulting Ltd | Administrative & support | 2015 |
| SAI Meera Properties Ltd | Real estate | 2023 |
| Saini Logistics London Ltd | Transport & logistics | 2024 |
| Sainovate Limited | Information & communication | 2022 |
| Saisri IT Solutions Limited | Information & communication | 2014 |
| Sajdera Construction Ltd | Construction | 2015 |
| Sajeev Stores Limited | Wholesale & retail | 2018 |
| Saku Real Estate Ltd | Real estate | 2020 |
| SAL21 Freight Limited | Transport & logistics | 2025 |
| Salahway Ltd | Wholesale & retail | 2014 |
| Salam E-Bikes Ltd | Wholesale & retail | 2025 |
| Salar Security Services Ltd | Administrative & support | 2025 |
| Salman Premier Ltd | Wholesale & retail | 2024 |
| Salt & Pepper Halal Meat Ltd | Wholesale & retail | 2025 |
| SAM Gregory Transport Ltd | Transport & logistics | 2023 |
| SAM Sky Construction Ltd | Construction | 2024 |
| SAM Wine & Food Limited | Wholesale & retail | 2013 |
| Samadee Global Trade & Sourcing Limited | Wholesale & retail | 2021 |
| Samarpan Consultancy Limited | Administrative & support | 2011 |
| Sambaaz Ltd | Other services | 2024 |
| Sami Tyre & Service Center Ltd | Wholesale & retail | 2020 |
| Samknows Limited | Administrative & support | 2008 |
| Samra Services Limited | Transport & logistics | 2016 |
| Samrddhi Properties Ltd | Real estate | 2026 |
| Samrdhh Ltd | Construction | 2025 |
| Samruddh Properties Limited | Real estate | 2023 |
| Samruddh Technologies Limited | Information & communication | 2022 |
| Samuel Pammi Group Ltd | Hospitality | 2026 |
| San-Levi's Ltd | Wholesale & retail | 2014 |
| Sandhu & Madho Limited | Transport & logistics | 2015 |
| Sandhu Gurdeep Ltd | Construction | 2023 |
| Sandhu Heating and Construction Ltd | Construction | 2020 |
| Sandhu Realty Limited | Real estate | 2023 |
| Saners Capital UK Ltd. | Financial services | 2020 |
| Saners Group Limited | Wholesale & retail | 2019 |
| Sannithiyaan Limited | Wholesale & retail | 2025 |
| Santos Innovates Paitings Limited | Construction | 2025 |
| Saon Ltd | Construction | 2016 |
| SAP (UK) Limited | Information & communication | 1987 |
| SAQ Accounting Services Ltd. | Professional & scientific | 1992 |
| Sarah Associates Ltd | Real estate | 2025 |
| Sarahvictoria Ltd | Wholesale & retail | 2015 |
| Saran Build Limited | Construction | 2018 |
| Sarao Roofing Ltd | Construction | 2025 |
| Sarawbi Limited | Hospitality | 2025 |
| Sarees and Beyond Limited | Wholesale & retail | 2025 |
| Sarhan Transport Limited | Transport & logistics | 2019 |
| Sarna Food & Wine Limited | Wholesale & retail | 2025 |
| Sarp Media Limited | Professional & scientific | 2016 |
| SAS Dwellings Ltd | Real estate | 2022 |
| SAS Team Recruitment UK Limited | Administrative & support | 2006 |
| Sasha Lofts Ltd | Construction | 2014 |
| Sasr Properties Limited | Real estate | 2021 |
| Sastec Ltd | Information & communication | 2025 |
| Satair UK Limited | Administrative & support | 1995 |
| Satman Holding Ltd | Financial services | 2026 |
| Saturn Tech Ltd | Wholesale & retail | 2025 |
| Savan Ltd | Manufacturing | 2021 |
| Savers Convenience Store Limited | Wholesale & retail | 2013 |
| Savino DEL Bene (UK) Limited | Transport & logistics | 1989 |
| Savino DEL Bene FDS UK Ltd | Transport & logistics | 2021 |
| Sawa Content Ltd | Wholesale & retail | 2019 |
| SB Capital Holdings Ltd | Financial services | 2022 |
| SB Capital Real Estate Management Ltd | Real estate | 2024 |
| SB Fadez Limited | Other services | 2021 |
| SC Building Construction Limited | Construction | 2023 |
| Scaffold Network Ltd | Construction | 2020 |
| Scent N Essence UK Ltd | Wholesale & retail | 2015 |
| Schembri and Singh Limited | Real estate | 2020 |
| Schnazz Ltd | Wholesale & retail | 2022 |
| Sci-Tex Limited | Wholesale & retail | 2018 |
| Scope Property Services Limited | Construction | 2011 |
| Scorleo Limited | Wholesale & retail | 2021 |
| Scouarnec Ltd | Construction | 2020 |
| Scruboss Ltd | Health & social care | 2024 |
| SD Events Photography Ltd | Professional & scientific | 2023 |
| Sdeol Ltd | Administrative & support | 2025 |
| SDI Contractors Ltd | Construction | 2011 |
| SDI Design and Build Limited | Construction | 2023 |
| Sdrk Trading Limited | Wholesale & retail | 2017 |
| Sea Moss UK Ltd | Wholesale & retail | 2020 |
| Seafrigo UK Limited | Other services | 2018 |
| Seaport Cargo Care UK Limited | Transport & logistics | 2018 |
| Sears Heating & Plumbing Ltd | Construction | 2014 |
| Season Business Consultancy Limited | Administrative & support | 2026 |
| Seb's Taxi Ltd | Transport & logistics | 2024 |
| Section 19 Training Ltd | Health & social care | 2021 |
| Securo Payroll Services (SPS) Ltd | Professional & scientific | 2026 |
| SED Props Ltd | Construction | 2022 |
| Seebi Consulting Limited | Professional & scientific | 2025 |
| Seetha Software Solutions Ltd | Information & communication | 2019 |
| Sehaj Contractors Limited | Construction | 2024 |
| Sekandar Limited | Wholesale & retail | 2025 |
| Sekhon and Nephews Ltd | Manufacturing | 2025 |
| Select Fit Limited | Wholesale & retail | 2026 |
| Sellant Ltd | Extraterritorial | 2023 |