| Deakin Holdings Limited | Administrative & support | 2022 |
| Deal Specsavers Limited | Wholesale & retail | 2005 |
| Deal Visionplus Limited | Wholesale & retail | 2005 |
| Dean Farrell Rail Services Ltd | Transport & logistics | 2023 |
| Deane Consultancy Limited | Professional & scientific | 2007 |
| DEB Fareham Limited | Hospitality | 2023 |
| Debra Joyce Hunt Limited | Extraterritorial | 2023 |
| Debra Joyce Maton Limited | Extraterritorial | 2023 |
| Debray Consulting Ltd | Professional & scientific | 2025 |
| DEC Advisory Ltd | Professional & scientific | 2026 |
| Deception Detection Education Ltd | Professional & scientific | 2015 |
| Decision Support Centre Limited | Administrative & support | 2024 |
| Deckchair Ventures Ltd | Information & communication | 2016 |
| Decor & More Property Services Ltd | Construction | 2023 |
| Deductive Reasoning Ltd | Professional & scientific | 2011 |
| DEE Caffari Ltd | Arts & recreation | 2006 |
| Deecom and Associates Limited | Construction | 1993 |
| Deep Blue Sea Media Limited | Administrative & support | 2016 |
| Deepdale Specsavers Limited | Wholesale & retail | 2017 |
| Deepwater Well Solutions Limited | Mining & quarrying | 2020 |
| Defacto Services Limited | Construction | 2016 |
| DEL Walsh Mechanical Services Limited | Construction | 2017 |
| Delaware Limited | Real estate | 1999 |
| Delfern Investments Limited | Real estate | 2023 |
| Delme Arms Limited | Hospitality | 2014 |
| Delme Property Ltd | Real estate | 2024 |
| Delo Software Limited | Information & communication | 2026 |
| Delta Finance Corporation Ltd | Financial services | 2000 |
| Delta Financial Management Limited | Financial services | 1980 |
| Delta Forge Limited | Extraterritorial | 2024 |
| Delta V Technologies Limited | Information & communication | 2017 |
| Delta-Hire Limited | Administrative & support | 2020 |
| Delta-Xero Distribution Limited | Manufacturing | 2012 |
| Deltaglobe Ltd | Extraterritorial | 2019 |
| Deltaglobe Two Limited | Administrative & support | 2016 |
| Delves Properties Limited | Real estate | 2021 |
| Denbigh Specsavers Limited | Wholesale & retail | 2018 |
| Denmead Driving Range Ltd | Arts & recreation | 2025 |
| Denmead Motor Repair Services Limited | Wholesale & retail | 2019 |
| Denmead Turf & Topsoil Ltd | Administrative & support | 2022 |
| Dent Dynasty Ltd | Health & social care | 2022 |
| Denton Specsavers Limited | Wholesale & retail | 2019 |
| Depesche (UK) Limited | Administrative & support | 2002 |
| Depthwise Group Limited | Professional & scientific | 2025 |
| Derby 1 Domiciliary Specsavers Limited | Wholesale & retail | 2014 |
| Derby Domi Audiology Specsavers Limited | Wholesale & retail | 2024 |
| Derby Specsavers Hearcare Limited | Wholesale & retail | 2004 |
| Derby Specsavers Limited | Wholesale & retail | 1988 |
| Derby Visionplus Limited | Wholesale & retail | 2002 |
| Derin Group Ltd | Wholesale & retail | 2014 |
| Derwen Associates Limited | Professional & scientific | 2017 |
| Desi Kravings Limited | Hospitality | 2025 |
| Design Analysis (UK) Limited | Manufacturing | 1998 |
| Design and Technical Solutions Limited | Professional & scientific | 2015 |
| Design Image Ltd | Administrative & support | 2005 |
| DESIGN5 IT Limited | Wholesale & retail | 2021 |
| DESTIN4 Ltd | Professional & scientific | 2021 |
| DET4 Security Services Ltd | Administrative & support | 2023 |
| Determinari Ltd | Information & communication | 2023 |
| DETERMINARI-001 Limited | Real estate | 2024 |
| Deuce Sports Ltd | Arts & recreation | 2017 |
| Develotec Design and Build Limited | Construction | 2015 |
| Develotec Electrical Southern Limited | Construction | 2023 |
| Develotec FM Ltd | Construction | 2023 |
| Develotec Limited | Construction | 2020 |
| Devitup Limited | Information & communication | 2023 |
| Devizes Specsavers Limited | Wholesale & retail | 2000 |
| DEY Kanti Property Solutions Limited | Households | 2024 |
| Deyi Limited | Hospitality | 2025 |
| DF Groundworks Ltd | Construction | 2010 |
| DF Holdings (Southern) Limited | Construction | 2014 |
| DFD Marine Ltd | Wholesale & retail | 2010 |
| DGC Property Services Ltd | Real estate | 2022 |
| DGN Consultancy Services Ltd | Information & communication | 2023 |
| DGW Marine Services Ltd | Professional & scientific | 2022 |
| DH & LH Services Limited | Information & communication | 2014 |
| DH Contracting Associates Limited | Manufacturing | 2012 |
| DH Divergence Ltd | Financial services | 2025 |
| Dhiraj Security Services Limited | Information & communication | 2011 |
| DI Turi & Veness Limited | Education | 2011 |
| Diabolo CUTZ9 Ltd | Other services | 2025 |
| Diamond Edge Professional Hair Limited | Other services | 2011 |
| Diamond GAS and Heating Limited | Construction | 2022 |
| Diamond Glow Cleaning Ltd | Administrative & support | 2024 |
| Diamond Green Energy Limited | Construction | 2011 |
| Diamond Heating & Cooling Limited | Construction | 2022 |
| Diamond Home Services Limited | Other services | 2016 |
| Diamond Quay Limited | Other services | 2013 |
| Diana Fashion UK Limited | Wholesale & retail | 2019 |
| Dibex Limited | Real estate | 2026 |
| Dice Property Limited | Real estate | 2020 |
| Didcot Specsavers Limited | Wholesale & retail | 2005 |
| Didcot Visionplus Limited | Wholesale & retail | 2005 |
| DIDO-2004 Ltd | Transport & logistics | 2019 |
| Diem Analytics Limited | Information & communication | 2011 |
| Diem Innovations Ltd | Information & communication | 2020 |
| Different Insurance Limited | Financial services | 2011 |
| Digbeth LOC Limited | Construction | 2022 |
| Digi Toolbox Ltd | Information & communication | 2007 |
| Digi-Impressions Limited | Manufacturing | 2012 |