| Felti Ltd | Wholesale & retail | 2015 |
| Fenchurch Decorating SW Ltd | Construction | 2025 |
| Feniton Park Limited | Construction | 2011 |
| Fenixsim Limited | Information & communication | 2020 |
| Fenrir Property Group 8 Ltd | Real estate | 2025 |
| Fenrir Property Group Limited | Real estate | 2018 |
| Fepp Ltd | Real estate | 2025 |
| Fermata UK Limited | Professional & scientific | 2013 |
| Fern & Forest Ltd | Professional & scientific | 2019 |
| Fern and Stone Ltd | Construction | 2025 |
| Fern Hair Salon Ltd | Other services | 2021 |
| Fern Property Investments Limited | Real estate | 2020 |
| Fernbank House Care Home Limited | Health & social care | 2021 |
| Fernhurst Lodge Ltd | Professional & scientific | 2022 |
| Fernlea International Ltd | Wholesale & retail | 2020 |
| Fernleigh Homes Management Company Limited | Households | 2020 |
| Feron Spires I.F.C Limited | Professional & scientific | 2000 |
| Ferris Productions Limited | Information & communication | 2017 |
| Ferris Town Ltd | Real estate | 2019 |
| Ferro & Farina Ltd | Hospitality | 2026 |
| Ferry Farm Solar Limited | Energy | 2013 |
| Ferry Lodge Financial Consulting Ltd | Professional & scientific | 2014 |
| Ferum Limited | Other services | 2023 |
| Festers Fencing and Landscaping Limited | Administrative & support | 2013 |
| Fetch 50 Ltd | Wholesale & retail | 2020 |
| Ffac C.I.C. | Education | 2024 |
| Ffcc Limited | Education | 2020 |
| FFF Jake Bristowe Limited | Arts & recreation | 2025 |
| Fflc Ltd | Real estate | 2025 |
| FGG Holdings Ltd | Real estate | 2025 |
| FHC Industries Ltd | Hospitality | 2020 |
| Fibre Network Construction Limited | Information & communication | 2023 |
| Fibrelok Limited | Manufacturing | 2021 |
| Fibrelok Products Limited | Other services | 2017 |
| Field Cable Services Group Ltd | Professional & scientific | 2022 |
| Field Mcneil Homes Limited | Construction | 2018 |
| Field Mcneil Limited | Real estate | 2017 |
| Field SW CIC | Education | 2023 |
| Fieldnote Futures Ltd | Information & communication | 2025 |
| Fieldworx Ltd | Agriculture & fishing | 2026 |
| Fierce Furrs Ltd | Wholesale & retail | 2025 |
| Fife Game and Varmint Control Limited | Agriculture & fishing | 2024 |
| Fifields Construction Limited | Construction | 2022 |
| Fifields Group Ltd | Construction | 2011 |
| Fifields Limited | Construction | 2002 |
| Fifteen Morton Crescent Exmouth Management Ltd. | Real estate | 2002 |
| Fiftyminds Ltd | Information & communication | 2023 |
| Figgy's Limited | Manufacturing | 2015 |
| Fika Salon Ltd | Other services | 2020 |
| Fika Studio Limited | Information & communication | 2016 |
| Fillies and Fizz Ltd | Hospitality | 2022 |
| Filmit Locations Limited | Professional & scientific | 2002 |
| Filofo Property Limited | Real estate | 2026 |
| Finance South West Business Loan Fund | | 2004 |
| Finance South West Growth Fund | | 2004 |
| Financial Goals Limited | Professional & scientific | 2023 |
| Financial Solutions Group Limited | Financial services | 2017 |
| Financially Smart Coaching Limited | Financial services | 2024 |
| Financy Ltd | Professional & scientific | 2024 |
| Finbar Homes Ltd | Real estate | 2023 |
| Find & Foster Fine Ciders Ltd | Manufacturing | 2025 |
| Find the Mountain Limited | Wholesale & retail | 2024 |
| Findatradie Limited | Administrative & support | 2025 |
| Findept Limited | Professional & scientific | 2013 |
| Fine and Country Exeter Limited | Real estate | 2021 |
| Fine Lines SW Limited | Construction | 2024 |
| Fingle Bridge Holdings Limited | Professional & scientific | 2004 |
| Fingle Farm Buildings Ltd | Construction | 2005 |
| Fink Publishing Limited | Information & communication | 2004 |
| Finn Environmental Holdings Ltd | Financial services | 2021 |
| Finoly Solutions Limited | Information & communication | 2025 |
| Finray IO Limited | Information & communication | 2022 |
| Finstore Limited | Real estate | 1991 |
| Fiona Wilkinson Limited | Professional & scientific | 2012 |
| FIP Consulting Limited | Professional & scientific | 2015 |
| Fire Alarm Services Ltd | Administrative & support | 2016 |
| Fire Alert UK Limited | Public administration | 2013 |
| Fire FOX Food Ltd | Hospitality | 2020 |
| Firebird (SW) Limited | Information & communication | 2007 |
| Firefighter Protection UK Limited | Wholesale & retail | 2009 |
| Firefly (Devon) Ltd | Real estate | 2022 |
| Firewalk Limited | Real estate | 2000 |
| Firm FIX South West Ltd | Construction | 2019 |
| Firmament Construction Ltd | Construction | 2026 |
| Firmplot Limited | Construction | 1992 |
| First Affinity Limited | Financial services | 2008 |
| First and Last Management Company Limited | Extraterritorial | 2016 |
| First Call Payment Protection Limited | Financial services | 2009 |
| First Choice Clearance Ltd | Water & waste | 2026 |
| First Choice Vending Ltd | Wholesale & retail | 2026 |
| First Databank UK Ltd | Information & communication | 1985 |
| First Key Property Investment Limited | Real estate | 2023 |
| First Light Communities C.I.C. | Extraterritorial | 2015 |
| First Light Optics Holdings Limited | Financial services | 2023 |
| First Light Optics Limited | Wholesale & retail | 2006 |
| FIRST2PROTECT Limited | Financial services | 2014 |
| FIRST4BUILDING Ltd | Construction | 2018 |
| FIRST4TECH Limited | Information & communication | 2006 |
| Firstcall MOT & Service Centre Ltd | Wholesale & retail | 2022 |
| Firstly Enterprises Ltd | Health & social care | 2024 |