| C & N Homes Limited | Real estate | 2025 |
| C & N Parsons Limited | Hospitality | 2017 |
| C & O Solutions Ltd | Construction | 2025 |
| C & P Contracting Solutions Ltd | Administrative & support | 2013 |
| C & R (SW) Interiors Ltd | Construction | 2019 |
| C & R Repairs Limited | Wholesale & retail | 2010 |
| C Andrews Consulting Ltd | Wholesale & retail | 2022 |
| C B Plumbing & Heating Ltd | Construction | 2015 |
| C C & R Holdings Limited | Real estate | 2025 |
| C C S Interiors SW Ltd | Construction | 2023 |
| C D Appliances Ltd | Wholesale & retail | 2022 |
| C D C Solutions Worldwide Ltd | Administrative & support | 2017 |
| C H P R C Limited | Wholesale & retail | 2011 |
| C I Developments Limited | Manufacturing | 2010 |
| C J Henry Screeding Ltd | Construction | 2020 |
| C J L Garage Doors Ltd | Construction | 2016 |
| C K Star Limited | Hospitality | 2008 |
| C L S (Properties) Limited | Construction | 1988 |
| C M Churchill Ltd | Professional & scientific | 2014 |
| C M Coaches Limited | Transport & logistics | 2014 |
| C M Water Economics Limited | Professional & scientific | 2012 |
| C Mears Property Ltd | Real estate | 2024 |
| C N Drinks Limited | Wholesale & retail | 2012 |
| C P Conversions Ltd | Construction | 2013 |
| C R Down Farming Limited | Agriculture & fishing | 2014 |
| C Reason Limited | Administrative & support | 1999 |
| C S L (SW) Ltd | Health & social care | 2021 |
| C S Plastering Contractors (SW) Limited | Construction | 2016 |
| C Squared Construct Limited | Construction | 2020 |
| C Squared Plant Limited | Administrative & support | 2020 |
| C T Landscapes Ltd | Administrative & support | 2012 |
| C View Technologies Limited | Professional & scientific | 2011 |
| C&C Properties Exeter Ltd | Construction | 2024 |
| C&G Property Holdings Ltd | Real estate | 2019 |
| C&L Holdings (SW) Ltd | Real estate | 2020 |
| C&L SW Property Solutions Limited | Real estate | 2025 |
| C&M Grange Court Ltd | Hospitality | 2015 |
| C&R Self Storage Ltd | Administrative & support | 2019 |
| C&S Interiors SW Ltd | Construction | 2024 |
| C-C Property Investment Limited | Real estate | 2018 |
| C-Storm Limited | Professional & scientific | 2025 |
| C. P. Sheds Ltd | Manufacturing | 2015 |
| C.C Upholstery Ltd | Manufacturing | 2026 |
| C.G.Y. (Miserve) Ltd | Manufacturing | 2010 |
| C.P. (Arts) Holdings Limited | Financial services | 2012 |
| C.P. (Arts) Limited | Manufacturing | 1976 |
| C.S.G.Pollitt Limited | Wholesale & retail | 1959 |
| C.T.P. Properties Limited | Real estate | 2005 |
| C4 Carriers Ltd | Financial services | 2002 |
| Caaab Group Ltd | Financial services | 2026 |
| CAB Devon | Other services | 2012 |
| Cabinet Studios Limited | Manufacturing | 2011 |
| Cablebuild Limited | Construction | 1984 |
| Cabona Properties Limited | Real estate | 2022 |
| Cadenza Academic Translations Ltd | Professional & scientific | 2012 |
| Caerisc Limited | Real estate | 1959 |
| Cafaros Limited | Wholesale & retail | 2023 |
| Cafesidemtb CIC | Arts & recreation | 2024 |
| Cainefisher 2022 Limited | Hospitality | 2022 |
| Cake Box Barnstaple Limited | Wholesale & retail | 2026 |
| Cake Box Exeter Limited | Wholesale & retail | 2025 |
| Cake OR Death Limited | Wholesale & retail | 2020 |
| Calbrema Enterprise Ltd | Professional & scientific | 2026 |
| Calicode Limited | Information & communication | 2019 |
| Callaware Ltd | Hospitality | 2021 |
| Callington Solar Park Limited | Energy | 2012 |
| Calmar Framing Ltd | Wholesale & retail | 2005 |
| Cam's Comps Ltd | Arts & recreation | 2025 |
| Camarasu Logistics Ltd | Transport & logistics | 2019 |
| Camber Solar Project Limited | Energy | 2015 |
| Cambria House RTM Company Ltd | Households | 2014 |
| Cambridge Surgical Ltd | Health & social care | 2017 |
| Came Scaffolding Limited | Construction | 2015 |
| Cameron Mills Group Limited | Education | 2025 |
| Camper Coffee Co. Ltd | Hospitality | 2012 |
| Camper HQ Ltd | Wholesale & retail | 2025 |
| Canberra Court Management Company Limited | Households | 1972 |
| Candia Systems Ltd | Information & communication | 2025 |
| Candor Properties Limited | Real estate | 2019 |
| Candour Projects Limited | Construction | 2012 |
| Cannings (Holdings) Limited | Professional & scientific | 2014 |
| Canns Down Press Limited | Information & communication | 2002 |
| Canon Southwest Limited | Extraterritorial | 2004 |
| Canonteign Events Limited | Arts & recreation | 2012 |
| Canonteign Falls Limited | Extraterritorial | 2013 |
| CAP Ceilings & Partitions Limited | Construction | 2003 |
| CAP Developments (Exeter) Limited | Financial services | 2021 |
| CAP Technologies Limited | Information & communication | 2019 |
| Capa Services (Exeter) Ltd | Administrative & support | 2025 |
| Capametrix Limited | Information & communication | 2020 |
| Capcad Limited | Professional & scientific | 1994 |
| Cape Cornwall Trading Co. Ltd | Wholesale & retail | 2023 |
| Cape Cross 2021 Limited | Financial services | 2021 |
| Capital & Centric (Resurrection) Limited | Construction | 2017 |
| Capital Build Group Ltd | Construction | 2026 |
| Capital Piling UK Ltd | Construction | 2021 |
| Capital Shift Ltd | Professional & scientific | 2001 |
| Capron Gould Limited | Real estate | 2009 |
| Car Body Shop Exeter Limited | Wholesale & retail | 2018 |
| Car Key DAN Ltd | Wholesale & retail | 2025 |