| Autonative Ltd | Information & communication | 2014 |
| Autopaint Ltd | Wholesale & retail | 2018 |
| Autopoint Car Sales (SW) Ltd | Wholesale & retail | 2024 |
| Autoservice and Spares Limited | Wholesale & retail | 2003 |
| Autoslm Ltd | Administrative & support | 2012 |
| Autotech Tuning Ltd | Wholesale & retail | 2021 |
| Auxilium Health Solutions Ltd | Health & social care | 2014 |
| Auxilium People Ltd | Administrative & support | 2024 |
| Auxin Developments Limited | Professional & scientific | 2025 |
| Avalon Bricklaying Limited | Construction | 2011 |
| Avanoss Limited | Hospitality | 2022 |
| Avari Care Ltd | Health & social care | 2026 |
| Aventi Global Limited | Professional & scientific | 2017 |
| Avery Developments (SW) Ltd | Construction | 2018 |
| Avery Knight & Bowlers Engineering Limited | Wholesale & retail | 1972 |
| Avgörande Limited | Wholesale & retail | 2022 |
| Aviation Associates Ltd | Transport & logistics | 2017 |
| Aviation South West Limited | Professional & scientific | 1999 |
| Avit Enterprises Limited | Real estate | 2018 |
| Avjones Limited | Water & waste | 2019 |
| Avocado Property Freehold Limited | Real estate | 2024 |
| Avocado Property Limited | Real estate | 2019 |
| Avocados Impact CIC | Education | 2020 |
| Avocet Ales Limited | Manufacturing | 2018 |
| Avocet Heron Ltd | Construction | 2015 |
| Avocet Legal Recruitment Ltd | Administrative & support | 2023 |
| Avocet Properties (SW) Ltd | Construction | 2022 |
| Avocet Property Investments Limited | Construction | 2021 |
| Avocet Recruitment Limited | Administrative & support | 2017 |
| Avocet Support Services Ltd | Health & social care | 2021 |
| Avon Bridge Machinery Limited | Agriculture & fishing | 1991 |
| Avon Valley Water Limited | Water & waste | 2008 |
| Avondale (S.W.) Ltd | Construction | 1986 |
| Avonside Plumbing & Heating (North East) Ltd | Wholesale & retail | 1985 |
| Avonside Plumbing & Heating (North West) Limited | Wholesale & retail | 1961 |
| Avonside Publishing Limited | Information & communication | 2002 |
| Avspares Ltd | Wholesale & retail | 2021 |
| Awardbox Limited | Extraterritorial | 2014 |
| Awarebrands Ltd | Wholesale & retail | 2018 |
| Awarelike Intelligence Limited | Information & communication | 2005 |
| AWC Spraying Services Limited | Construction | 2024 |
| Awesome Classic & Custom Ltd | Administrative & support | 2019 |
| Awesome Mortgages Ltd | Financial services | 2020 |
| AWP (Exeter) LLP | | 2024 |
| AWP Medical Reports Ltd | Health & social care | 2023 |
| AXE Vale Developments Limited | Real estate | 2026 |
| Axiomera Health Ltd | Health & social care | 2026 |
| Axis Accounts Limited | Professional & scientific | 2002 |
| Axis Ceilings and Partitions Limited | Construction | 2018 |
| Axminster (Contracts) Limited | Wholesale & retail | 2020 |
| Axminster Carpets Limited | Wholesale & retail | 2020 |
| Axxora (UK) Limited | Wholesale & retail | 1995 |
| AY Complete Limited | Wholesale & retail | 2026 |
| Ayad Commercials Limited | Construction | 2024 |
| Aycheck Holdings Ltd | Real estate | 2025 |
| Ayersmont (H) Limited | Financial services | 2024 |
| Ayersmont Limited | Financial services | 1989 |
| Aylesbeare Barns (Management) Company Limited | Professional & scientific | 2000 |
| AYO (SW) Ltd | Hospitality | 2024 |
| AYO Exeter Ltd | Hospitality | 2024 |
| Ayre Investments Limited | Real estate | 2021 |
| Ayzey Homefoods Ltd | Hospitality | 2025 |
| AZ Flooring Specialist Limited | Construction | 2003 |
| Azebra Group Ltd | Administrative & support | 2013 |
| Azimuth Offshore Limited | Mining & quarrying | 2005 |
| Azure Sky Holding Limited | Real estate | 2016 |
| Azure Vehicle Body Repairs Ltd | Wholesale & retail | 2012 |
| Azuspirits Ltd | Wholesale & retail | 2019 |
| Azzurro Blue Ltd | Manufacturing | 2025 |
| B & a Exmouth Ltd | Hospitality | 2021 |
| B & C Renovations Ltd | Construction | 2020 |
| B & D Partners Limited | Financial services | 2021 |
| B & Family Futures Ltd | Real estate | 2024 |
| B & H (SW) Ltd | Hospitality | 2019 |
| B & K Mayflower Properties Ltd | Real estate | 2024 |
| B & L Construction Services Limited | Construction | 1998 |
| B & M Coatings Limited | Construction | 2010 |
| B a Housing Ltd | Construction | 2017 |
| B and a Cafe Limited | Hospitality | 2025 |
| B BEE Holdings Limited | Financial services | 2025 |
| B Williams Holdings Ltd | Professional & scientific | 2025 |
| B&D Logistics Ltd | Transport & logistics | 2025 |
| B&M Property Partners Ltd | Real estate | 2025 |
| B.A. (NO.1) Limited | Extraterritorial | 1991 |
| B.A. Wright Building Ltd | Construction | 2016 |
| B.A.R. North Devon Properties Ltd | Real estate | 2023 |
| B.G. Pearce Limited | Construction | 2001 |
| B.K. Racing Limited | Wholesale & retail | 1997 |
| B.N.R.C Ltd | Construction | 2022 |
| B.Pierce Quality Solutions Limited | Professional & scientific | 2005 |
| B.T. Gray | | 2009 |
| Babilim Light Industries Limited | Information & communication | 2013 |
| Baby Panda Theatre Limited | Arts & recreation | 2025 |
| Baby Sensory and Toddler Sense Plympton South Hams Ltd | Education | 2022 |
| Babylon SW87 Limited | Hospitality | 2025 |
| Babylonshaji Ltd | Hospitality | 2025 |
| BAC Property Limited | Real estate | 2019 |
| Bace Surveyors Ltd | Professional & scientific | 2021 |
| Back to Earth (SW) Limited | Wholesale & retail | 2009 |
| BAD Balloon Limited | Arts & recreation | 2016 |