| Deisas Properties Ltd | Real estate | 2024 |
| Dele Housing Limited | Real estate | 2025 |
| Delelyn Services and Konsultancy Limited | Financial services | 2021 |
| Delightful Kids Limited | Health & social care | 2026 |
| Delphina's Vanity Studio Ltd | Other services | 2019 |
| Demi Services Ltd | Transport & logistics | 2022 |
| Demitay Ltd | Information & communication | 2025 |
| Demmayoque Services Limited | Education | 2016 |
| Deneva Rose UK Limited | Hospitality | 2025 |
| Denisa Supermarket Ltd | Wholesale & retail | 2015 |
| Dennibim Care Services Limited | Health & social care | 2019 |
| Denny Care Limited | Health & social care | 2022 |
| Dental Composite Limited | Manufacturing | 1986 |
| Dentervie Co. Limited | Other services | 2001 |
| Dequams Limited | Transport & logistics | 2014 |
| Dequor Ltd | Other services | 2012 |
| Dermic UK Limited | Construction | 2015 |
| Design Space Ltd | Wholesale & retail | 2010 |
| Desmay-Ik Ltd | Health & social care | 2019 |
| Destella Ltd | Professional & scientific | 2025 |
| Destomy Limited | Health & social care | 2018 |
| Deuces Records Ltd | Wholesale & retail | 2019 |
| DFI Healthcare Limited | Health & social care | 2016 |
| Dfk-It Limited | Information & communication | 2018 |
| Dgitech Solutions Ltd | Information & communication | 2024 |
| Dgitech Travels Limited | Administrative & support | 2024 |
| DGN Domestic Services Limited | Construction | 2022 |
| Dhaliwal Express Ltd | Transport & logistics | 2025 |
| Dhaliwal Private Limited | Information & communication | 2025 |
| Dhaliwal Tech Solutions Ltd | Information & communication | 2026 |
| Dhemeson UK Limited | Agriculture & fishing | 2025 |
| Dhillon Development & Holdings Ltd | Construction | 2020 |
| Dhyavaa Limited | Professional & scientific | 2015 |
| Diadem Immigration Solutions Ltd | Professional & scientific | 2026 |
| Diamenn Limited | Information & communication | 2023 |
| Diamond Cosmetics UK Limited | Wholesale & retail | 2016 |
| Diamond Getaways Ltd | Real estate | 2024 |
| Diamonds in Concrete CIC | Information & communication | 2024 |
| Digital Accountax Ltd | Professional & scientific | 2025 |
| Digital Asset Marketing Ltd | Professional & scientific | 2025 |
| Digital IT Store Ltd | Information & communication | 2018 |
| Digital Mobstars Ltd | Other services | 2014 |
| Digital Topside Ltd | Information & communication | 2026 |
| Digitalatd Limited | Extraterritorial | 2018 |
| Dilan Barbers 1 Ltd | Other services | 2024 |
| Dilawit Mulugeta Kahsay Limited | Health & social care | 2023 |
| Diligent NDT and Inspection Ltd | Construction | 2025 |
| Dimension One Kitchens & Bedrooms Limited | Wholesale & retail | 2008 |
| Dine Together Ltd | Information & communication | 2025 |
| Direct Diamond Ltd | Construction | 2019 |
| Direct Global Limited | Administrative & support | 2015 |
| Direct International Limited | Professional & scientific | 2010 |
| Discount Cars (South East) Ltd | Wholesale & retail | 2010 |
| Discount Property Services Ltd | Real estate | 2015 |
| Dito Digital Ltd | Information & communication | 2026 |
| Diveforge Auto Parts Ltd | Wholesale & retail | 2026 |
| Divine Impression Limited | Other services | 2015 |
| Divine Care 247 Limited | Health & social care | 2012 |
| Divine Links Ltd | Hospitality | 2009 |
| Divine Path Supplies Limited | Health & social care | 2021 |
| Divine Rock Limited | Health & social care | 2022 |
| Divine Support Services Limited | Health & social care | 2013 |
| Divinefield Solicitors Ltd | Professional & scientific | 2023 |
| Diya Chicken Ltd | Hospitality | 2022 |
| DJP Windows Doors Ltd | Construction | 2025 |
| DJV Distribution Ltd | Wholesale & retail | 2022 |
| DKJ Care Resources Limited | Health & social care | 2019 |
| DL Roofing Specialists Ltd | Extraterritorial | 2023 |
| DLG Services Group Ltd | Professional & scientific | 2026 |
| Dm&Daughters Ltd | Professional & scientific | 2021 |
| DN on Point Ltd | Health & social care | 2014 |
| DNB Heating Ltd | Construction | 2023 |
| Doctor's Daughter Ltd | Health & social care | 2015 |
| Dog and Outdoors Limited | Wholesale & retail | 2024 |
| Dogs Running Free Ltd | Other services | 2014 |
| Dokey Global Ventures Limited | Wholesale & retail | 2026 |
| Doltravo Ltd | Wholesale & retail | 2025 |
| Dominion General Services Limited | Administrative & support | 2015 |
| Dominion Pharmaceuticals Ltd | Wholesale & retail | 2021 |
| Dominion World Limited | Transport & logistics | 2014 |
| Domlido Limited | Health & social care | 2012 |
| Dorin Transport Services Limited | Transport & logistics | 2018 |
| Dosunmu Ltd | Real estate | 2021 |
| Dotos Limited | Other services | 2009 |
| Double J Boxing Gym Ltd | Arts & recreation | 2018 |
| Double Z Lipgloss Ltd | Wholesale & retail | 2025 |
| Doulas Without Borders CIC | Health & social care | 2020 |
| DP Builders & Construction (Holdings) Limited | Construction | 2016 |
| DP Builders & Construction (Properties) Limited | Real estate | 2016 |
| Dprs Construction Ltd | Construction | 2020 |
| DRB Constructions Limited | Construction | 2018 |
| Dream Lofts Ltd | Construction | 2023 |
| DRS Kent Limited | Transport & logistics | 2010 |
| Dryf Limited | Transport & logistics | 2017 |
| Dsrpt Music Limited | Arts & recreation | 2020 |
| DUB HUT Camper Kitchens Ltd | Wholesale & retail | 2022 |
| Dubthugs Ltd | Wholesale & retail | 2025 |
| Duby Ltd | Hospitality | 2021 |
| Duccat Ltd | Construction | 2024 |
| Ductrix Ltd | Construction | 2025 |