| Singh Motors Ltd | Wholesale & retail | 2023 |
| Singla Consulting Europe Ltd | Wholesale & retail | 2020 |
| Singla Consulting Worldwide Ltd | Information & communication | 2019 |
| Sips Galore Ltd | Manufacturing | 2025 |
| Sirius Research & Innovation Limited | Information & communication | 2024 |
| Sita Spices Limited | Manufacturing | 2001 |
| Sivani Residential Ltd | Real estate | 2024 |
| Skipidy Skip Transport Limited | Transport & logistics | 2025 |
| Sky Melody Clothing Limited | Wholesale & retail | 2025 |
| Skybourne Travels Ltd | Administrative & support | 2018 |
| Sleyvick Properties Ltd | Real estate | 2025 |
| Slsc Gibson Ltd | Real estate | 2019 |
| Slyfox Limited | Information & communication | 2012 |
| SM Property Collective Ltd | Real estate | 2026 |
| Smalldoo Ltd | Administrative & support | 2022 |
| Smart Technology UK Inc Ltd | Construction | 2018 |
| SMD Property Management Solutions Ltd | Real estate | 2025 |
| SMF Properties Ltd | Real estate | 2024 |
| Smile Aligners Ltd | Wholesale & retail | 2025 |
| SMT Invest Ltd | Real estate | 2018 |
| Snuggleez Limited | Wholesale & retail | 2021 |
| SOAFA3 Limited | Real estate | 2023 |
| Soas Consultancy Limited | Real estate | 2025 |
| Social Distance Management Services Ltd | Wholesale & retail | 2020 |
| Social Learning Centre Limited | Education | 2012 |
| Society for the Advancement & Sustenance of Yoruba Language & Culture (Sayslc) C.I.C. | Education | 2022 |
| Socrates Worldwide Ltd | Wholesale & retail | 2024 |
| Soflow Limited | Administrative & support | 2023 |
| Soft Hour Events Ltd | Hospitality | 2026 |
| Soin Ltd | Health & social care | 2026 |
| Soka Blackmore Limited | Wholesale & retail | 2001 |
| Solaris Services Ltd | Real estate | 2023 |
| Solo Plumbing Ltd | Construction | 2026 |
| Solutions Consult Ltd | Mining & quarrying | 2012 |
| Solutions Embassy Limited | Health & social care | 2018 |
| Solvana Innovation Ltd | Professional & scientific | 2025 |
| Somiden Limited | Real estate | 2026 |
| Sonia Heway Care Agency Ltd | Health & social care | 2008 |
| Sorted Studio Ltd | Information & communication | 2025 |
| Sosan Group Ltd | Wholesale & retail | 2026 |
| Soula Soul Events Ltd | Administrative & support | 2025 |
| Soundboard Evolution Limited | Professional & scientific | 2023 |
| Source by Nature Ltd | Wholesale & retail | 2020 |
| South East England Minicab Syndicate Ltd | Transport & logistics | 2025 |
| South London Fire Protection Limited | Construction | 2025 |
| Sovereign Property Solutions Ltd | Real estate | 2021 |
| Soyebeyko Limited | Public administration | 2019 |
| Spanner Works Recovery Ltd | Wholesale & retail | 2025 |
| Sparrows Landscaping Ltd | Administrative & support | 2021 |
| SPC Tilling Ltd | Construction | 2019 |
| Spectrum Workplace Education Consulting Ltd | Professional & scientific | 2019 |
| Speedy Constructions Ltd | Construction | 2020 |
| Spice Experience Ltd | Hospitality | 2020 |
| Springland Housing Ltd | Real estate | 2021 |
| Springlite Resources Ltd | Health & social care | 2025 |
| Springs of Hope PVT Limited | Health & social care | 2025 |
| Sprintdraft Ltd | Information & communication | 2026 |
| Squareways Ltd | Information & communication | 2013 |
| SS Rawr Sales Ltd | Wholesale & retail | 2025 |
| SSA Property Developers Ltd | Real estate | 2021 |
| SSP Accountancy Solutions Limited | Professional & scientific | 2022 |
| ST Deodatus Limited | Administrative & support | 2015 |
| ST JAY Solutions Ltd | Construction | 2017 |
| ST Paul Care Support Limited | Administrative & support | 2020 |
| ST. John's Pens Limited | Wholesale & retail | 2023 |
| St.Eve Surfacing Limited | Construction | 2013 |
| Stacey JAY Lockley Limited | Professional & scientific | 2019 |
| Standard Electrical Contractors Ltd | Construction | 2024 |
| Standard Wharf Limited | Transport & logistics | 2013 |
| Standoc Limited | Health & social care | 2016 |
| Stanmore Brickwork Limited | Extraterritorial | 2019 |
| Stanmore Carpentry Limited | Extraterritorial | 2019 |
| Stanmore Contractors Limited | Construction | 1992 |
| Stanmore Decorating Limited | Extraterritorial | 2019 |
| Stanmore Design House Limited | Construction | 2016 |
| Stanmore Drylining Limited | Extraterritorial | 2018 |
| Stanmore Facades Limited | Extraterritorial | 2018 |
| Stanmore Fire Proofing Ltd | Extraterritorial | 2018 |
| Stanmore Glazing Limited | Extraterritorial | 2018 |
| Stanmore Holdings Limited | Professional & scientific | 2018 |
| Stanmore Homes Limited | Extraterritorial | 2018 |
| Star Anodising & Finishing Holdings Limited | Financial services | 2025 |
| Star Automotive Ltd | Wholesale & retail | 2013 |
| Star Janitorial Supplies Limited | Wholesale & retail | 1987 |
| Starburger (Erith) Ltd | Hospitality | 2014 |
| Starlight Royalle Investments Limited | Real estate | 2021 |
| Starlight Solar Ltd | Construction | 2014 |
| Start Education Limited | Education | 2024 |
| Steep House Ltd | Wholesale & retail | 2026 |
| Steines Ltd | Information & communication | 2019 |
| Stelbeks Limited | Public administration | 2019 |
| Stend Autos Ltd | Administrative & support | 2025 |
| Step to Change Woeif Ltd | Health & social care | 2024 |
| Steward Properties Limited | Real estate | 2015 |
| Stfc Limited | Administrative & support | 2012 |
| Still Waters Health Limited | Arts & recreation | 2014 |
| Stirling Transport Limited | Transport & logistics | 2003 |
| Stone Hause Ltd | Manufacturing | 2019 |
| STONE4LIFE Ltd | Construction | 2012 |
| STONE4LIFE Properties Limited | Real estate | 2022 |