| Omora Limited | Professional & scientific | 2025 |
| Oneeuropas Holding Group Ltd | Wholesale & retail | 2025 |
| Ontime Cruisers Limited | Transport & logistics | 2024 |
| Opes Healthcare UK Limited | Manufacturing | 2025 |
| Optimus Security Services Ltd | Administrative & support | 2024 |
| Oxfordeast Learning Ventures Limited | Information & communication | 2023 |
| Park Blue Group Holdings Limited | Financial services | 2025 |
| Passion Bamboo Seeds Ltd | Wholesale & retail | 2022 |
| Patrician Systems Ltd | Professional & scientific | 2006 |
| Paula Louise Pritchard Ltd | Wholesale & retail | 2026 |
| PDC Trading Ltd | Wholesale & retail | 2026 |
| Pedro Ltd | Hospitality | 2019 |
| Pedwin Developments Ltd | Construction | 2025 |
| Pet Niverse Ltd | Wholesale & retail | 2025 |
| Phrenzie Limited | Other services | 2012 |
| Physical Layer Ltd | Information & communication | 2026 |
| Pika Vapor Limited | Wholesale & retail | 2024 |
| Pixmoses Ltd | Extraterritorial | 2019 |
| PJS Point Ltd | Professional & scientific | 2026 |
| Precision Ariel Ltd | Construction | 2026 |
| Premier Prime Retail Ltd | Wholesale & retail | 2026 |
| Pristine Auto Services Ltd | Wholesale & retail | 2024 |
| Pro Composite Recycling Ltd | Water & waste | 2022 |
| Protegrity Europe Limited | Information & communication | 2001 |
| Pure Elegance Event Hire Ltd | Hospitality | 2026 |
| Pure Event Hire Ltd | Administrative & support | 2026 |
| Quellpod Ltd | Information & communication | 2026 |
| Quoin Estates Ltd | Real estate | 2021 |
| Radiant Medics Ltd | Health & social care | 2023 |
| Raidealshub Ltd | Wholesale & retail | 2026 |
| Ravensbourne Management Services Limited | Administrative & support | 2011 |
| Re-Solution Data Holdings Ltd | Financial services | 2024 |
| Reboost & GLO Aesthetic Clinic Ltd | Professional & scientific | 2016 |
| Reborn Life Limited | Administrative & support | 2024 |
| Red Hot World Buffet Ltd | Hospitality | 2019 |
| Reema Zulfiqar Ltd | Wholesale & retail | 2025 |
| Regal Johns UK Ltd | Wholesale & retail | 2025 |
| Regent Letting and Property Management Limited | Real estate | 2012 |
| Reliable Punching Ltd | Wholesale & retail | 2024 |
| RG14 Investments Ltd | Financial services | 2026 |
| Rigun Limited | Information & communication | 2026 |
| Rock and RAY Limited | Real estate | 2023 |
| Ruach Consultancy Limited | Health & social care | 2025 |
| S&B(Uk) Ltd | Wholesale & retail | 2026 |
| S.H.A.V.E. Morris Limited | Real estate | 2023 |
| Sa&Pvt Ltd | Wholesale & retail | 2023 |
| Safe Tags SS Limited | Wholesale & retail | 2024 |
| Saffron Ivory Limited | Arts & recreation | 2013 |
| Sagor Ltd | Wholesale & retail | 2026 |
| Salespremium Ltd | Wholesale & retail | 2026 |
| Salon Catalina Ltd | Other services | 2021 |
| Salut Cars Ltd | Wholesale & retail | 2024 |
| Sanskriti Services Limited | Wholesale & retail | 2017 |
| Santa Transport Ltd | Transport & logistics | 2023 |
| SAS Trade Ltd | Wholesale & retail | 2026 |
| SCG Masterminds Ltd | Education | 2026 |
| Sebo Trading Limited | Wholesale & retail | 2024 |
| Secure Access Technologies Limited | Administrative & support | 2012 |
| Senshanbog Ltd | Extraterritorial | 2013 |
| Shandong Heng Gang Bearing Co., Ltd | Extraterritorial | 2018 |
| Shenzhen Fashion Boss Electrical Appliances Co., Ltd. | Manufacturing | 2019 |
| Shirdi SAI Limited | Other services | 2018 |
| Shols Ltd | Transport & logistics | 2025 |
| Shree PS Limited | Real estate | 2020 |
| Simaliya Investment Limited | Financial services | 2024 |
| Smar Properties Ltd | Real estate | 2022 |
| Smartbrains IT Solutions Ltd | Information & communication | 2022 |
| Smith & Nephew Extruded Films Limited | Professional & scientific | 1957 |
| Smith & Nephew Medical Limited | Professional & scientific | 1958 |
| Soniyaluby Enterprises Ltd | Administrative & support | 2026 |
| Specialist Tooling Services Limited | Wholesale & retail | 2022 |
| SPH Specialist Vehicles Limited | Wholesale & retail | 2019 |
| Sree Krishna Power Engineering and Consultancy Ltd | Construction | 2026 |
| ST. Jude's Medical Consulting Ltd | Professional & scientific | 2024 |
| Starmore Construction Ltd | Construction | 2026 |
| Staycation Homes Ltd | Real estate | 2021 |
| Stem Club Bushey Ltd | Education | 2025 |
| Stem Club Southgate Ltd | Education | 2025 |
| Steritech Engineering Services Limited | Professional & scientific | 2012 |
| Sterling Solutions London Limited | Information & communication | 2022 |
| Stoneside Capital Ltd | Wholesale & retail | 2022 |
| Sudbrooke Holdings Limited | Financial services | 2017 |
| Suman Infotech Limited | Information & communication | 2023 |
| Sumanhousing Ltd | Real estate | 2026 |
| Supastrikers Wigan Ltd | Arts & recreation | 2025 |
| Super Shiny Northwick HCW Ltd | Other services | 2024 |
| Supplyhaus Ltd | Wholesale & retail | 2026 |
| SYL Battery UK Limited | Manufacturing | 2022 |
| Syntax Enterprises Limited | Construction | 1984 |
| T.J.Smith and Nephew,Limited | Manufacturing | 1907 |
| Tafseer Raheemi Ltd | Education | 2014 |
| Tankuokuo Zkhe Ltd | Wholesale & retail | 2024 |
| TCV Consulting Ltd | Administrative & support | 2026 |
| Team-Made Furniture Co., Ltd | Wholesale & retail | 2022 |
| Teamelody Limited | Wholesale & retail | 2025 |
| Techno & Samba Ltd | Hospitality | 2026 |
| Terminal 6 Studio Ltd | Information & communication | 2026 |
| Tessallite Ltd | Information & communication | 2026 |
| Thameside Contemporary Double Glazing Services Ltd | Construction | 2004 |
| THE 9PM Club Ltd | Professional & scientific | 2026 |