| Sftw Limited | Wholesale & retail | 2020 |
| SG Property Sourcing Ltd | Financial services | 2022 |
| Sgbs Services Ltd | Other services | 2015 |
| SGE Contractors Limited | Construction | 2018 |
| SGR Rigging Ltd | Construction | 2019 |
| SH & N Property Ltd | Real estate | 2023 |
| SH Electrical & Construction Ltd | Construction | 2018 |
| Shabbysheek Ltd | Wholesale & retail | 2025 |
| Shadan Care Services Limited | Health & social care | 2014 |
| Shadow FS Ltd | Real estate | 2025 |
| Shadow K9 Limited | Administrative & support | 2021 |
| Shahed Property Management Ltd | Real estate | 2023 |
| Shahid Painter & Decorator Ltd | Construction | 2024 |
| Shahini Properties Ltd | Real estate | 2025 |
| Shahs Enfield Ltd | Hospitality | 2025 |
| Shai Services Ltd | Professional & scientific | 2018 |
| Shalom Haven Ltd | Health & social care | 2026 |
| Sham Estate Ltd | Real estate | 2024 |
| Shamis Health and Beauty Ltd | Health & social care | 2020 |
| Shanley Plumbing and Heating Ltd | Construction | 2024 |
| Shanpepee Morning Star Media Limited | Information & communication | 2024 |
| Shape-Up Services Limited | Professional & scientific | 2015 |
| Sharav Properties Ltd | Real estate | 2021 |
| Shareholder Partner LP | | 2018 |
| Sharen Global Ltd | Wholesale & retail | 2025 |
| Sharon Cruz PT Limited | Health & social care | 2024 |
| Sharon Healthcare Limited | Health & social care | 2014 |
| Sharon’S Care Limited | Health & social care | 2019 |
| Sharp Sparks Limited | Information & communication | 2006 |
| Sharyar Holdings Limited | Wholesale & retail | 2024 |
| Shavic Limited | Health & social care | 2019 |
| Shaydee Ltd | Wholesale & retail | 2025 |
| Shears Consulting Ltd | Professional & scientific | 2018 |
| Sheelpa Express Ltd | Wholesale & retail | 2017 |
| Sheer Indulgence (Rochford) Limited | Other services | 2005 |
| Shehata Property Developments Limited | Extraterritorial | 2023 |
| Shekinah Books Ltd | Education | 2013 |
| Shekinah Lumu House Limited | Health & social care | 2019 |
| Shelby Staffing and Consulting Ltd | Administrative & support | 2023 |
| Shelec 78 Limited | Construction | 2008 |
| Shelf 2 Ltd | Construction | 2017 |
| Shellington Avenue CIC | Professional & scientific | 2026 |
| Shelpe Limited | Education | 2022 |
| Shelterscape Ltd | Real estate | 2024 |
| Sheni Building Ltd | Construction | 2026 |
| Shepherd Harris & Co Limited | Professional & scientific | 2014 |
| Sherdale Consultants Limited | Professional & scientific | 1993 |
| Sherifi Group Ltd | Construction | 2021 |
| Sherkob Ltd | Transport & logistics | 2025 |
| Sherwood Close (Phase 3) LLP | | 2024 |
| Shine Beauty Clinic Ltd | Other services | 2026 |
| Shine Showcase Event Ltd | Administrative & support | 2024 |
| Shineworks Cleaning Ltd | Administrative & support | 2023 |
| Shinny Enterprise Limited | Wholesale & retail | 2024 |
| Ship Shaip Plastering Ltd | Construction | 2025 |
| Ship Shape Shipping Shop Ltd | Administrative & support | 2024 |
| Shiraz Mobile Tyres Ltd | Wholesale & retail | 2026 |
| Shiroda Consulting Limited | Professional & scientific | 2016 |
| Shishly Grill & Meze Limited | Hospitality | 2020 |
| SHK Fish Bar Ltd | Hospitality | 2020 |
| SHL (Film & TV) Limited | Information & communication | 2008 |
| SHM Capital Management Limited | Real estate | 2018 |
| SHM Management Consulting Limited | Professional & scientific | 2019 |
| SHM Property Investments Limited | Real estate | 2022 |
| SHN Solutions Limited | Professional & scientific | 2014 |
| Shoebox Events Ltd | Information & communication | 2024 |
| Sholem Health & Social Care Limited | Health & social care | 2020 |
| Shoogarush Ltd | Administrative & support | 2023 |
| Shopsn Ltd | Wholesale & retail | 2025 |
| Shoreham Nails and Spa Limited | Other services | 2023 |
| Short Side Ltd | Information & communication | 2024 |
| Shortlisters Limited | Information & communication | 2006 |
| Shpata Construction Limited | Construction | 2023 |
| Shreetrade Limited | Wholesale & retail | 2019 |
| Shulev Properties Ltd | Real estate | 2022 |
| Si&Yu Property Ltd | Real estate | 2025 |
| Siamel Property Investments Ltd | Real estate | 2026 |
| Sibley Engineering Limited | Administrative & support | 2016 |
| Siby Ltd | Information & communication | 2013 |
| Siby Property Solutions Ltd | Real estate | 2024 |
| Sida Properties Ltd | Real estate | 2020 |
| Sidekick Support Ltd | Administrative & support | 2020 |
| Sidney Avenue Management Limited | Real estate | 2014 |
| Sierra Holdings UK Ltd | Real estate | 2016 |
| Sigma Contractor Services Ltd | Information & communication | 2026 |
| Sign Wave Electrical Limited | Construction | 2021 |
| Signalhome Ltd | Administrative & support | 1998 |
| Signature Circuit Solutions Ltd | Construction | 2026 |
| Signature Cookware Limited | Wholesale & retail | 2010 |
| Signature Designs Ltd | Manufacturing | 2025 |
| Signature Development Group Ltd | Construction | 2026 |
| Signature Mark Ltd | Transport & logistics | 2022 |
| Sila Cargo UK Limited | Transport & logistics | 2024 |
| Silan Fish Bar Limited | Hospitality | 2025 |
| Sileagle Inter Limited | Households | 2022 |
| Silk Beauty London Limited | Other services | 2018 |
| Silka Interiors Ltd | Real estate | 2021 |
| Silky Nail & Beauty Limited | Other services | 2021 |
| Silver 1975 Logistics Ltd | Transport & logistics | 2025 |
| Silver Build Ltd. | Construction | 2017 |