| Upplo EDU Limited | Education | 2021 |
| Upstage Theatrical DRY Cleaners Limited | Other services | 2003 |
| Upstairs Downstairs Hair Salon Limited | Other services | 2020 |
| Urartus Design London Ltd | Construction | 2016 |
| Urastar Construction Ltd | Construction | 2021 |
| Urba Environmental Services Limited | Water & waste | 2019 |
| Urban Food Centre Limited | Wholesale & retail | 2025 |
| Urban Gateway Ltd | Real estate | 2023 |
| Urfa Kebab Limited | Hospitality | 2019 |
| Urmi's Chai Ltd | Manufacturing | 2025 |
| URS Business Solutions Ltd | Information & communication | 2024 |
| USA Chicken Soham Ltd | Hospitality | 2025 |
| USA Fast Food Ltd | Hospitality | 2026 |
| USA Nails & Shellac Limited | Other services | 2022 |
| Ushii Ltd | Real estate | 2024 |
| Ushii Pro Limited | Information & communication | 2026 |
| Usimii Ltd | Professional & scientific | 2011 |
| Utch Consultant Limited | Professional & scientific | 2011 |
| Utika Ltd | Information & communication | 2007 |
| UXK Logistics Ltd | Transport & logistics | 2025 |
| UZ Gold Ltd | Wholesale & retail | 2025 |
| Uzene Limited | Information & communication | 1996 |
| UZI Doner Ltd | Hospitality | 2024 |
| Uzun Deco & Design Ltd | Construction | 2025 |
| Uzun Property Limited | Real estate | 2019 |
| Uzuri Jewellery Ltd | Wholesale & retail | 2021 |
| V B & Sons Ltd | Real estate | 2024 |
| V Bala Ltd | Construction | 2016 |
| V C B Services Limited | Construction | 2015 |
| V Cota Brickwork Ltd | Construction | 2017 |
| V I Corporate Ltd | Professional & scientific | 2005 |
| V I Estate Management Ltd | Real estate | 2013 |
| V I O Solution Limited | Administrative & support | 2025 |
| V Nail & Spa Limited | Other services | 2019 |
| V Top Fitness Ltd | Other services | 2019 |
| V&N Drywall Ltd | Construction | 2017 |
| V&S Coffee Limited | Real estate | 2025 |
| V&V Holistic Care Ltd | Health & social care | 2025 |
| V-Blue Limited | Manufacturing | 2021 |
| V.L.V Nails Salon Limited | Other services | 2020 |
| V.N. Investment Holdings Limited | Wholesale & retail | 2016 |
| V.T.V Building Ltd | Construction | 2020 |
| V2K Premium Limited | Wholesale & retail | 2025 |
| Vaiga Consultancy Services Ltd | Information & communication | 2014 |
| Valencrest Holdings Ltd | Real estate | 2026 |
| Valentine Care Recruitment Limited | Administrative & support | 2022 |
| Valestone Trading Limited | Other services | 2017 |
| Valito Solution Ltd | Health & social care | 2025 |
| Valley Loft Conversions Ltd | Construction | 2012 |
| Valor Group Limited | Other services | 2024 |
| Value Creation Education Limited | Education | 2018 |
| Vamos for Schools Limited | Administrative & support | 2022 |
| Vamp London Ltd | Wholesale & retail | 2011 |
| Van BAO Tran Limited | Other services | 2025 |
| Van Vliet UK Ltd | Wholesale & retail | 2019 |
| Vandal Blue Ltd | Wholesale & retail | 2026 |
| Vanderpump & Sykes LLP | | 2010 |
| Vani Limited | Health & social care | 2012 |
| Vanko Builders Ltd | Construction | 2023 |
| Vanlei Collections Ltd | Wholesale & retail | 2023 |
| Vanquis Security Ltd | Administrative & support | 2016 |
| Vanquish Fitness Limited | Wholesale & retail | 2014 |
| Vans Construction Limited | Administrative & support | 2024 |
| Vans Tidy UK Limited | Manufacturing | 2025 |
| Vany Limited | Manufacturing | 2020 |
| Vareston Ltd | Wholesale & retail | 2025 |
| Varity Merchants Ltd | Wholesale & retail | 2026 |
| Varley & Varley Limited | Other services | 2014 |
| Varney Management Services Limited | Other services | 2026 |
| Varsha PVT Limited | Wholesale & retail | 2018 |
| Vasco DEC Limited | Construction | 2025 |
| Vasil 2015 Construction Ltd | Construction | 2015 |
| Vasilev SD Company Ltd | Construction | 2025 |
| VASSERVICES13 Limited | Transport & logistics | 2017 |
| Vata Logistics Transport UK Ltd | Transport & logistics | 2024 |
| Vata Tiling Ltd | Construction | 2023 |
| Vatamanu Trans Limited | Transport & logistics | 2018 |
| Vault Chamber Investment Group Limited | Financial services | 2025 |
| Vavito Ltd | Construction | 2014 |
| Vayda Construction Ltd | Administrative & support | 2015 |
| VBO Lounge & Bar Limited | Hospitality | 2018 |
| VBS Ltd | Construction | 2020 |
| VDL Construction Ltd | Construction | 2011 |
| VDM Group Ltd | Construction | 2019 |
| VDW Civils Ltd | Financial services | 2026 |
| Vectral Infrastructure Capital Limited | Professional & scientific | 2025 |
| Vedansh Tech Ltd | Information & communication | 2020 |
| Veenuuk Ltd | Wholesale & retail | 2020 |
| Vega Systems Limited | Professional & scientific | 1989 |
| Vegaci Ltd | Information & communication | 2025 |
| Vegan Advocate Limited | Hospitality | 2019 |
| Veglito Structures LP | | 2017 |
| Vehicles on Demand Limited | Administrative & support | 2026 |
| Vektron Ltd | Wholesale & retail | 2026 |
| Velar Entertainment Ltd | Arts & recreation | 2024 |
| Velina Limited | Other services | 2008 |
| Velmora Goods Ltd | Wholesale & retail | 2026 |
| Velo X Supply Chain Limited | Transport & logistics | 2024 |
| Velta Limited | Hospitality | 2018 |
| Velvet Vanity Ltd | Real estate | 2025 |