| Strange Pixels Ltd | Information & communication | 2013 |
| Stranmere Ltd | Extraterritorial | 2006 |
| Strat Consulting Ltd | Professional & scientific | 2014 |
| Stratahub Limited | Information & communication | 2026 |
| Stratos Automotive Ltd | Wholesale & retail | 2025 |
| Stratos Chauffeurs Ltd | Transport & logistics | 2026 |
| Straw Enterprises Ltd | Financial services | 2025 |
| Strawberrycars. UK. Ltd | Water & waste | 2017 |
| Strazhmark Ltd | Administrative & support | 2024 |
| Street Stripes Ltd | Administrative & support | 2023 |
| Street Wallet Ltd | Administrative & support | 2025 |
| Street WF Ltd | Hospitality | 2025 |
| Streetmicpod Ltd | Information & communication | 2020 |
| Streets Away Properties Ltd | Real estate | 2019 |
| Streetsounds Tracking Solutions Ltd | Construction | 2020 |
| Strictly Solid Ltd | Wholesale & retail | 2020 |
| Strides Adult Care Services Ltd | Health & social care | 2024 |
| Strides Childcare Services Ltd | Health & social care | 2020 |
| Strides Holdings Limited | Financial services | 2024 |
| Strides Housekeeping Services Ltd | Administrative & support | 2024 |
| Strides Property Investments Limited | Real estate | 2024 |
| Strides Recruitment Ltd | Administrative & support | 2023 |
| Strike Three Design Ltd | Arts & recreation | 2016 |
| Strikeco (2) Limited | Professional & scientific | 1947 |
| Strive Health Limited | Information & communication | 2024 |
| STS Complete Health & Safety Limited | Administrative & support | 2008 |
| Stuart Ward Cabinets Ltd | Construction | 2021 |
| Stubborngrass Limited | Wholesale & retail | 2012 |
| Student Supreme Ltd | Education | 2022 |
| Studio Alpha Ltd. | Professional & scientific | 2022 |
| Studio Amatys Ltd | Other services | 2025 |
| Studio E8 Ltd | Real estate | 2026 |
| Studio Lock 16 Ltd. | Arts & recreation | 2020 |
| Studio Williams Ltd | Professional & scientific | 2025 |
| Studyvisor Limited | Education | 2025 |
| STUFF2SEND Limited | Information & communication | 2008 |
| Stunga Ltd | Construction | 2019 |
| Style by Lewis Ltd | Wholesale & retail | 2026 |
| Style Nails (Andover) Limited | Other services | 2018 |
| Styled Clothing Limited | Wholesale & retail | 2016 |
| Stylee Ltd | Wholesale & retail | 2025 |
| Stylers Room Ltd | Other services | 2025 |
| Styles Unisex Salon (SUS) Limited | Other services | 2016 |
| Stylias Ltd | Manufacturing | 2025 |
| Stylishchicks Ltd | Wholesale & retail | 2026 |
| Suang YU Trading Co Ltd | Wholesale & retail | 2025 |
| Suave Ltd | Other services | 2010 |
| Suave Props Ltd | Real estate | 2025 |
| SUB Zero Climate Limited | Construction | 2025 |
| Subash Import & Export Ltd | Wholesale & retail | 2022 |
| Subcon Limited | Construction | 1993 |
| Subset Solutions UK Limited | Information & communication | 2015 |
| Subware LLP | | 2020 |
| Sudbury Court Property Ltd | Real estate | 2021 |
| Sudbury Jones (Frames) Limited | Manufacturing | 1981 |
| Sudhir Medical Services Limited | Health & social care | 2013 |
| Sudi Consulting Limited | Information & communication | 2025 |
| Sugar Quay Capital Limited | Arts & recreation | 2024 |
| Sugar Realm Ltd | Financial services | 2012 |
| Sugar Tea Room Ltd | Manufacturing | 2021 |
| SUI Generis Entertainment Ltd | Hospitality | 2023 |
| Sula Pahlavan Property Management Ltd | Real estate | 2025 |
| Sula Real Estate Limited | Real estate | 2022 |
| Sullivan Tanner Limited | Information & communication | 2023 |
| Sully Build Group Ltd | Administrative & support | 2024 |
| Summer Luxe Nails Limited | Other services | 2023 |
| Summit 364 Limited | Wholesale & retail | 2017 |
| Summit Business Portal Limited | Wholesale & retail | 2025 |
| Summit London Ltd | Construction | 2019 |
| Summit Vitalis Ltd | Wholesale & retail | 2025 |
| Sun & Sun Limited | Hospitality | 2019 |
| Sun Delivery Logistics Ltd | Wholesale & retail | 2020 |
| Sun N Salt Ltd | Hospitality | 2025 |
| Sunbrothers Ltd | Construction | 2018 |
| Sunion Health Ltd | Health & social care | 2018 |
| Sunlight Roofing Ltd | Construction | 2025 |
| Sunny Bars Ltd | Hospitality | 2025 |
| Sunrise Accounting Ltd | Professional & scientific | 2019 |
| Sunrise Data Development Ltd | Information & communication | 2019 |
| Sunshine Coast Catering (Property) Ltd | Real estate | 2020 |
| Sunshine Psychology Ltd | Health & social care | 2025 |
| Supando Limited | Information & communication | 2017 |
| Superior Goods UK Ltd | Wholesale & retail | 2026 |
| Superme Ltd | Wholesale & retail | 2020 |
| Superstar Clothing Ltd | Wholesale & retail | 2005 |
| Support and Help Family Limited | Transport & logistics | 2025 |
| Support IS US Limited | Health & social care | 2020 |
| Supracontinental Ltd | Wholesale & retail | 2021 |
| Supreme Organisation of Syrian Expatriates Ltd | Professional & scientific | 2025 |
| Suretrak Limited | Wholesale & retail | 2014 |
| Suretrak Solutions Limited | Other services | 2015 |
| Suri Construction Ltd | Construction | 2022 |
| Suri Nails Penicuik Limited | Other services | 2022 |
| Surrey Sports Equipment Ltd | Manufacturing | 2018 |
| SUS Finance Ltd | Financial services | 2025 |
| Sussex & Kent Roofing Ltd | Construction | 2023 |
| Sussex Live Limited | Arts & recreation | 2025 |
| Sussy Services Limited | Administrative & support | 2014 |
| Sustainability Unscripted Limited | Professional & scientific | 2023 |
| Sutogna Ltd | Wholesale & retail | 2025 |