| Right Dose Limited | Professional & scientific | 2017 |
| Riley Life Limited | Real estate | 2024 |
| Ringstone Recruitment Limited | Administrative & support | 2011 |
| Rise Lane House Management Company Limited | Households | 2005 |
| Riverview RTM Company Limited | Households | 2022 |
| RJK Property Ltd | Real estate | 2024 |
| RNK Renewables Limited | Energy | 2011 |
| Robertshaw & Sons Ltd | Wholesale & retail | 2025 |
| Robinson Associates Stone Consultants Limited | Professional & scientific | 1998 |
| Robinsons Greenhouses Limited | Professional & scientific | 2010 |
| Roby Road Management Company Limited | Households | 2006 |
| Rochdale Rajas Limited | Hospitality | 2023 |
| Rockrite Limited | Manufacturing | 1996 |
| Rokesby Place Management Company Limited | Households | 2019 |
| Rol-Trac (Automatic Doors) Limited | Manufacturing | 1992 |
| Roots Whole Food Market Ltd | Wholesale & retail | 2020 |
| Rouaida Jewellery Ltd | Manufacturing | 2019 |
| Roundhead Holdings Ltd | Real estate | 2024 |
| Routec Investments Limited | Wholesale & retail | 2019 |
| Routec UK Limited | Manufacturing | 2004 |
| Roxy Venue (Sowerby Bridge) Ltd | Hospitality | 2013 |
| RSK Fastenings Limited | Wholesale & retail | 2002 |
| RSK Holdings (Halifax) Limited | Financial services | 2018 |
| RTM Water Royd Limited | Real estate | 2008 |
| Rubeez E-Liquids Ltd | Wholesale & retail | 2017 |
| Rugby Buddy Limited | Professional & scientific | 2024 |
| Rusty's Coffee Club Ltd | Hospitality | 2020 |
| Ryburn Medical Services Ltd | Health & social care | 2017 |
| Ryburn Pharmacy (Ripponden) Limited | Wholesale & retail | 2003 |
| S and R Local Store Ltd | Wholesale & retail | 2024 |
| S Burland Electrical Services Ltd | Construction | 2017 |
| S E G Yorkshire Ltd | Construction | 2026 |
| S Hopkinson GAS Heating & Plumbing Limited | Construction | 2022 |
| S K S Engineering & Machine Services Limited | Manufacturing | 1998 |
| S Marshall & Sons Limited | Professional & scientific | 2002 |
| S P M Creative Consulting Limited | Administrative & support | 2016 |
| S'N's Spaces Limited | Other services | 2016 |
| S.E.Robinson Scaffolding (WY) Ltd | Construction | 2023 |
| S2 Fire Solutions Limited | Other services | 2010 |
| Saddleworth Road Property Management Company Limited | Households | 2004 |
| Safeguru Group Limited | Wholesale & retail | 2021 |
| Safeguru UK Limited | Wholesale & retail | 2021 |
| Salts Security Systems Limited | Construction | 2008 |
| SAM Weller Holdings Limited | Manufacturing | 1999 |
| Samplerite Limited | Wholesale & retail | 1993 |
| Samuel Court (Cudworth) Management Company Limited | Households | 2006 |
| Sand Traders Ltd | Real estate | 2020 |
| Sandfield Yorkshire Ltd | Hospitality | 2018 |
| Sarah Banks Coaching Ltd | Other services | 2016 |
| Saves Direct Limited | Wholesale & retail | 2013 |
| Savile Grange Management Company Limited | Households | 2007 |
| Saxon Hollow Management Company Limited | Households | 2006 |
| Sayjo Recruitment Limited | Administrative & support | 2015 |
| SB Motors (Yorkshire) Limited | Wholesale & retail | 2026 |
| SBK Stores Ltd | Wholesale & retail | 2017 |
| SBS Fencing & Groundworks Ltd | Construction | 2026 |
| Scenic Blue (UK) Limited | Professional & scientific | 1996 |
| Scenic Blue Landscape Franchise Limited | Professional & scientific | 2000 |
| Scenic Blue Limited | Professional & scientific | 1997 |
| Schofield & Smith (Huddersfield) Limited | Manufacturing | 1950 |
| Scholes Fisheries Limited | Hospitality | 2018 |
| SCM Properties Yorkshire Limited | Real estate | 2020 |
| Scribble Stone Limited | Manufacturing | 2012 |
| SD Painservices PVT Ltd | Health & social care | 2023 |
| Sea Blue Fisheries Limited | Hospitality | 2023 |
| Seal IT Services Limited | Manufacturing | 2002 |
| Seamless Design Ltd | Information & communication | 2018 |
| Searchlight Employment Law Solutions Limited | Professional & scientific | 2014 |
| SEE Ahead | Professional & scientific | 2011 |
| Sell US Your Apple Ltd | Wholesale & retail | 2018 |
| SGE Store Ltd | Wholesale & retail | 2025 |
| Shark! Design & Marketing Limited | Professional & scientific | 2006 |
| Shaw Mills Harrogate Management Company Limited | Real estate | 2024 |
| Shear Tech Textile Engineers Limited | Manufacturing | 2017 |
| Shellietastic Creativity Limited | Education | 2021 |
| Shine Business Management Ltd | Professional & scientific | 2023 |
| Shoe Hunt UK Limited | Wholesale & retail | 2026 |
| Simply Group North Ltd | Financial services | 2019 |
| Simply Moving and Sleeping Ltd | Administrative & support | 2012 |
| Sitesocket Ltd | Wholesale & retail | 2024 |
| Sixteen Real Estate (Building Consultancy) Limited | Professional & scientific | 2019 |
| Sixteen Real Estate (Industrial) Ltd | Real estate | 2017 |
| Sixteen Real Estate (Offices) Ltd | Real estate | 2026 |
| Sixteen Real Estate (Professional) Ltd | Real estate | 2020 |
| Sixteen Real Estate Ltd | Real estate | 2016 |
| SJK Developments Limited | Real estate | 2018 |
| Sjmg Properties Limited | Real estate | 2025 |
| SJS Commercial Holdings Limited | Real estate | 2026 |
| Skircoat Lodge Management Company Limited | Households | 2001 |
| Small Lees Mill (Ripponden) Management Company Limited | Households | 2000 |
| Smart Eire Guard Solutions Ltd | Other services | 2023 |
| Smart Eire Management Solutions Ltd | Administrative & support | 2022 |
| Smart Eire Support Solutions Ltd | Other services | 2022 |
| Smart Energy Solutions Ltd | Energy | 2024 |
| Smart Éire Group Ltd | Other services | 2024 |
| Smithies Properties Limited | Real estate | 2026 |
| SNT Trading Limited | Administrative & support | 2007 |
| Solea Studio Ltd | Other services | 2026 |
| Solefactory Ltd | Wholesale & retail | 2015 |
| Soleresponsibility Limited | Wholesale & retail | 2020 |