| Empire Sail Business LP | | 2016 |
| Empire Smart LP | | 2016 |
| Empire State Investments LP | | 2016 |
| Empire Technology LP | | 2015 |
| Empireco Limited | Wholesale & retail | 2021 |
| Empirica Advisory LP | | 2014 |
| Empirical Consult Scotland Ltd | Construction | 2018 |
| Emporio Skumand LP | | 2011 |
| Empower Electrical Edinburgh Ltd | Construction | 2019 |
| Empower United Limited | Construction | 2025 |
| Empower Your Health Limited | Health & social care | 2023 |
| Empowerdei Limited | Professional & scientific | 2023 |
| Empowered by Cloud Ltd | Administrative & support | 2017 |
| Empowered Life Coaching Co. Ltd | Professional & scientific | 2023 |
| Empowered Pathways Ltd | Education | 2022 |
| Empowering YOU Limited | Professional & scientific | 2022 |
| Empowerment Scotland Ltd | Health & social care | 2024 |
| Empowerwell Limited | Professional & scientific | 2025 |
| Empresio Management LP | | 2016 |
| Empress Business LP | | 2016 |
| Empress Treasure Investments LP | | 2016 |
| Empros Media Ltd | Professional & scientific | 2025 |
| Empros Retail Ltd | Professional & scientific | 2021 |
| Empsych Ltd | Health & social care | 2022 |
| Emres Scotland Ltd | Hospitality | 2015 |
| EMS Media Services Limited | Wholesale & retail | 2022 |
| EMY Management LP | | 2024 |
| EN Dealhub Limited | Wholesale & retail | 2026 |
| EN Pointe Solutions Ltd | Hospitality | 2015 |
| En&De LP | | 2014 |
| En-Able Academy Limited | Education | 2023 |
| Enabling Health Limited | Health & social care | 2003 |
| Enabling Trades Companies Limited | Professional & scientific | 2023 |
| Enact (CIP) GP LLP | | 2019 |
| Enact Design Limited | Professional & scientific | 2015 |
| Enact I (CIP) Limited Partnership | | 2013 |
| Enact I Nominee Limited Partnership | | 2013 |
| Enact II (CIP) L.P. | | 2019 |
| Enact II (GP) LP | | 2019 |
| Enact III (CIP) L.P. | | 2021 |
| Enact III (GP) L.P. | | 2021 |
| Enact III GP LLP | | 2021 |
| Enarg LP | | 2013 |
| ENASEHA2 Ltd | Wholesale & retail | 2024 |
| ENC Travel Management Ltd. | Transport & logistics | 2018 |
| Encapsulate Transport Solutions Limited | Professional & scientific | 2024 |
| Encephalon Limited | Other services | 2024 |
| Enchance Division LP | | 2017 |
| Enchanted Business Solutions LP | | 2016 |
| Enclave Solutions Ltd | Education | 2015 |
| Enco Trade LP | | 2014 |
| Encom Tech LP | | 2016 |
| Encompass Icoe Limited | Professional & scientific | 2016 |
| Encompass Security Scotland Ltd | Administrative & support | 2026 |
| Encompassing Limited | Information & communication | 2009 |
| Encontro Street Band Festival Limited | Arts & recreation | 2018 |
| Encore Lets Limited | Real estate | 2024 |
| Encore Property Management Ltd | Real estate | 2025 |
| Encore Transit LP | | 2015 |
| END 2 END Construction Management Ltd | Professional & scientific | 2025 |
| Endellion Brown LP | | 2011 |
| Endgame Legal Consultancy Limited | Professional & scientific | 2017 |
| Endison Ventilation Ltd | Construction | 2015 |
| Endless (CIP) Limited Partnership | | 2008 |
| Endless (GP) LP | | 2008 |
| Endless Carry LLP | | 2011 |
| Endless First Partner Limited | Financial services | 2011 |
| Endless III (CIP) Limited Partnership | | 2011 |
| Endless III (GP) LP | | 2011 |
| Endless III General Partner LLP | | 2011 |
| Endless IV (CIP) LP | | 2014 |
| Endless IV (GP) LLP | | 2014 |
| Endless IV (GP) LP | | 2014 |
| Endless Second Partner Limited | Financial services | 2011 |
| Endless Star Group LP | | 2016 |
| Endless Strategic Investments I (CIP) LP | | 2019 |
| Endless Strategic Investments I (GP) LP | | 2019 |
| Endless V (CIP) LP | | 2019 |
| Endless V (General Partner) LLP | | 2018 |
| Endless V (GP) LP | | 2019 |
| Endless VI (CIP) LP | | 2026 |
| Endless VI (GP) LLP | | 2026 |
| Endo Bloom LP | | 2023 |
| Endocryne Limited | Agriculture & fishing | 2019 |
| Endoplant Invest LP | | 2015 |
| Endpoint Automation Services Limited | Information & communication | 2014 |
| Endpoint Clinical (UK) Limited | Administrative & support | 2017 |
| Endri Invest LP | | 2011 |
| Endrick Property Collection Ltd | Real estate | 2025 |
| Endura Ltd. | Manufacturing | 1990 |
| Endurance Sport Performance Ltd | Education | 2020 |
| Enemy Films Ltd | Information & communication | 2020 |
| Enercon Wind Energy UK Limited | Construction | 2019 |
| Energeios EV Ltd | Manufacturing | 2025 |
| Energised Electrical Group Limited | Construction | 2024 |
| Energised Electrical Testing Ltd | Professional & scientific | 2024 |
| Energised Environments Limited | Professional & scientific | 2013 |
| Energised Ventures Limited | Professional & scientific | 2014 |
| Energize Aesthetic Ltd | Health & social care | 2017 |
| Energize Electrical (Scot) Ltd | Construction | 2021 |