| Stanway Tyres Limited | Manufacturing | 2021 |
| Stanwick Car Care Ltd | Administrative & support | 2026 |
| Stanwick Hand Car Wash & Valet Ltd | Administrative & support | 2026 |
| Star Secure Ltd | Administrative & support | 2016 |
| Starcatcher Consulting Limited | Professional & scientific | 2022 |
| Stardale Limited | Wholesale & retail | 1984 |
| Stargate Capital Investment Group Limited | Financial services | 2003 |
| Starglow Finance Limited | Financial services | 2006 |
| Starglow Holdings Ltd | Financial services | 2021 |
| Stark Consultancy Limited | Administrative & support | 2023 |
| Starlight Films Limited | Information & communication | 1995 |
| Starline London Ltd | Wholesale & retail | 2026 |
| Starlink Build Ltd | Construction | 2025 |
| Starlink Technology Limited | Administrative & support | 2016 |
| Starmall Limited | Construction | 1999 |
| Stars International Supply Chain Ltd | Administrative & support | 2023 |
| Starshine DRY Cleaners Limited | Other services | 2006 |
| Startup Autos Limited | Wholesale & retail | 2017 |
| Starwaves Enterprises Ltd | Manufacturing | 2025 |
| Station 26 Limited | Hospitality | 2017 |
| Station Butchers Centre Ltd | Wholesale & retail | 2024 |
| Stature Properties Ltd | Real estate | 2019 |
| Stavros Brekoulakis Limited | Other services | 2012 |
| Stay Social UK Limited | Other services | 2014 |
| STB Chicken Limited | Hospitality | 2025 |
| Stead-Fast Rock UK Limited | Wholesale & retail | 2021 |
| Stealth Leisure Limited | Arts & recreation | 1996 |
| Steeple Dental Ltd | Health & social care | 2017 |
| Stefan Delivery Ltd | Transport & logistics | 2021 |
| Stefano Limited | Construction | 2006 |
| Stellara Collective Ltd | Wholesale & retail | 2025 |
| Step Accounting Limited | Professional & scientific | 2020 |
| Step in Ltd | Wholesale & retail | 2018 |
| Stephen Conrad Limited | Transport & logistics | 2003 |
| Stephen Taylor Architects Limited | Professional & scientific | 2002 |
| Steppaz Limited | Health & social care | 2020 |
| Stepstation Ltd | Education | 2026 |
| Sterling Plus One Ltd | Wholesale & retail | 2024 |
| Sterling White Limited | Real estate | 2022 |
| Sterom TJ Construction Limited | Construction | 2019 |
| Steshop Ltd | Wholesale & retail | 2020 |
| Steven N Bailey Limited | Real estate | 2025 |
| Steven Plautus Limited | Real estate | 2017 |
| Steyne Enterprises Ltd | Real estate | 2022 |
| STF Ductwork Ltd | Manufacturing | 2019 |
| STF Property Investment UK Limited | Real estate | 2018 |
| STG Enterprise Ltd | Wholesale & retail | 2025 |
| Still Lives Limited | Arts & recreation | 2024 |
| Stirling Moss Builders Limited | Construction | 2023 |
| Stirling Property Investments Ltd | Real estate | 2014 |
| Stitch to Fit Limited | Manufacturing | 2025 |
| STK Consortium 4 Limited | Construction | 2020 |
| STK Consortium 5 Limited | Construction | 2020 |
| STK Developments 1 Limited | Construction | 2022 |
| Stoica and Sons Ltd | Other services | 2023 |
| Stoica Landscapes Ltd | Administrative & support | 2013 |
| Stoicacs Ltd | Information & communication | 2024 |
| Stone Medics Ltd | Construction | 2009 |
| Stonecircle One Life Live IT Limited | Wholesale & retail | 2012 |
| Stonecrest Home Maintenance Ltd | Construction | 2024 |
| Stonegrove Community Trust | Health & social care | 2014 |
| Stop at Picacadilly Ltd | Wholesale & retail | 2023 |
| Stories by Bhavin Ltd | Information & communication | 2025 |
| Strada Wrld Ltd | Wholesale & retail | 2024 |
| Straight Business Solutions Ltd | Professional & scientific | 2026 |
| Strambu Ltd | Construction | 2016 |
| Strategy Square Ltd | Education | 2024 |
| Strats Consulting Services Limited | Administrative & support | 2012 |
| Stratwicks Holdings Ltd | Wholesale & retail | 2025 |
| Stratwicks Investments Ltd | Real estate | 2025 |
| Stratwicks Warwick Ltd | Wholesale & retail | 2025 |
| Streamline Health Systems Limited | Wholesale & retail | 2023 |
| Streatnod Ltd | Real estate | 2019 |
| Strength & Grace Ltd | Real estate | 2022 |
| Strenth Installations Limited | Construction | 2015 |
| Stressman Engineering Ltd | Administrative & support | 2011 |
| Strexor Limited | Wholesale & retail | 2012 |
| Strider Management Consultants Limited | Professional & scientific | 2018 |
| Strings Estate Planning Limited | Professional & scientific | 2020 |
| Stringsfp Limited | Financial services | 2019 |
| Stripe Media Ltd | Information & communication | 2010 |
| Strippers Paint Removers Limited | Administrative & support | 2019 |
| Strong EYE Care Ltd | Health & social care | 2023 |
| Strong Tower Study Limited | Information & communication | 2026 |
| Studdridge Investments Limited | Financial services | 2018 |
| Student Space Limited | Hospitality | 2016 |
| Studio Asso Limited | Professional & scientific | 2025 |
| Studio INI Ltd | Professional & scientific | 2015 |
| Studio Nahorniak Limited | Professional & scientific | 2022 |
| Studio Sarah Limited | Professional & scientific | 2016 |
| Studiopop Ltd | Information & communication | 2023 |
| Study-Worldwide Limited | Education | 2012 |
| Style & Tech Limited | Wholesale & retail | 2026 |
| Su-Man Skincare Limited | Health & social care | 2011 |
| SUB Studio Limited | Professional & scientific | 2025 |
| Subby Solutions Ltd | Construction | 2011 |
| Subzero Productions Limited | Hospitality | 2021 |
| Success Brand Ltd | Manufacturing | 2023 |
| Successful Strategies Limited | Professional & scientific | 2012 |
| Suceava Supermarket Ltd | Wholesale & retail | 2026 |