| Smke Ltd | Wholesale & retail | 2017 |
| SMM PVT Ltd | Real estate | 2026 |
| Smoke Customer Intelligence Ltd. | Information & communication | 2015 |
| SMR Assets Limited | Real estate | 2023 |
| SMSH13 Ltd | Hospitality | 2025 |
| SN 185 Limited | Administrative & support | 2016 |
| SN Star Services Ltd | Real estate | 2023 |
| Sn&Op Construction Ltd | Construction | 2020 |
| SN6 Estates Limited | Real estate | 2021 |
| SN6 Ltd | Financial services | 2019 |
| Snackville Ltd | Wholesale & retail | 2019 |
| Snap Clothing Ltd | Wholesale & retail | 2025 |
| Snapcap Ltd | Financial services | 2025 |
| Snapsign Limited | | 1981 |
| SND Drylining Ltd | Construction | 2016 |
| Sneaky FOX Ltd | Wholesale & retail | 2021 |
| SNG Homes Limited | Real estate | 2016 |
| Sniro Ltd | Information & communication | 2010 |
| Snooze Events Limited | Arts & recreation | 2025 |
| Snow Flow Films Ltd | Information & communication | 2024 |
| Snowstraw Limited | Professional & scientific | 2013 |
| SNS Impex (PVT) Ltd | Wholesale & retail | 2007 |
| Snug & Chill Limited | Construction | 2014 |
| Sobh Ltd | Construction | 2025 |
| Soccer Chance Academy Ltd | Education | 2017 |
| Soccer Chance USA Limited | Arts & recreation | 2012 |
| Social Audience Studios Ltd | Information & communication | 2018 |
| Social Chai Media Management Ltd | Manufacturing | 2023 |
| Social Diners Ltd | Professional & scientific | 2021 |
| Social Stars Limited | Other services | 2012 |
| Socreative Solutions Ltd | Information & communication | 2024 |
| Soflau Ltd | Manufacturing | 2025 |
| SOFT15 Limited | Information & communication | 2025 |
| Softecho Ltd | Wholesale & retail | 2025 |
| Sognamold Limited | Professional & scientific | 2023 |
| Sohaib Fatimi Solicitors (UK) Limited | Professional & scientific | 2016 |
| Sokoswift Limited | Professional & scientific | 2026 |
| SOL Books Limited | Education | 2021 |
| SOL Laboratories Limited | Information & communication | 2022 |
| Solana Leisure Limited | Hospitality | 2023 |
| Solanki Properties Limited | Real estate | 2020 |
| Solberge Hall Hotel Ltd | Hospitality | 2005 |
| Soldany Trans Ltd | Transport & logistics | 2018 |
| Solida Bathrooms Ltd | Wholesale & retail | 2019 |
| Solitaire Health & Beauty (UK) Limited | Other services | 2007 |
| Solmore Limited | Professional & scientific | 2024 |
| Solo Plastering Ltd | Construction | 2024 |
| Solomei Tourism Limited | Administrative & support | 2017 |
| Solomon Excel Ltd | Real estate | 2021 |
| Solon Estate Planning Limited | Professional & scientific | 2022 |
| Solphie Properties Ltd | Real estate | 2021 |
| Solum Estates Ltd | Real estate | 2017 |
| Solum Property Management Limited | Real estate | 2021 |
| Solwick Limited | Other services | 1978 |
| Someco Ltd | Wholesale & retail | 2023 |
| Somerset View Property Ltd | Real estate | 2024 |
| Somesa Limited | Professional & scientific | 2022 |
| Sonbury Limited | Professional & scientific | 2025 |
| SONGS2LEARN Ltd | Wholesale & retail | 2023 |
| Soniae Ltd | Wholesale & retail | 2013 |
| Sonjac Property Consultants Ltd | Administrative & support | 2019 |
| Sonnenfeld Accounts Ltd | Professional & scientific | 2022 |
| Sons & M Ltd | Professional & scientific | 2026 |
| Sophan Limited | Health & social care | 2017 |
| Sorea Plastering Ltd | Construction | 2021 |
| Sorin Services Ltd | Construction | 2025 |
| Sorriso Capital Ltd | Professional & scientific | 2025 |
| Sorttax Limited | Information & communication | 2024 |
| Soshusbell Limited | Professional & scientific | 2017 |
| Souline Limited | Real estate | 2025 |
| SOURCE8RITE Ltd | Professional & scientific | 2018 |
| South Facing Limited | Real estate | 2023 |
| Southbank Court Maisonettes (3-6) Limited | Real estate | 2014 |
| Southbridge (Croydon) RTM Company Limited | Households | 2016 |
| Southmore Properties Ltd | Extraterritorial | 2012 |
| Southview House Management Limited | Real estate | 2003 |
| Sovereign Park Estates Ltd | Real estate | 2023 |
| Soye Ltd | Financial services | 2024 |
| SP Audio Limited | Information & communication | 2019 |
| SP Revolution Ltd | Construction | 2019 |
| SP Tax Services Ltd | Professional & scientific | 2025 |
| SP90 Ltd | Real estate | 2021 |
| Space Modern Ltd | Wholesale & retail | 2022 |
| Space Residential (London) Limited | Real estate | 2003 |
| Spaceline Limited | Real estate | 2015 |
| Spaisha Ltd | Health & social care | 2009 |
| Span Consultants UK Ltd | Information & communication | 2011 |
| Spanayu Ltd | Real estate | 2024 |
| Sparkle and Shiny Ltd | Administrative & support | 2017 |
| Sparkling Auto Hub Ltd | Wholesale & retail | 2024 |
| Sparkly CM Limited | Health & social care | 2017 |
| Sparlon Limited | Professional & scientific | 2004 |
| Sparquote Limited | Other services | 1982 |
| Sparx Aero Limited | Wholesale & retail | 2022 |
| Spas Corporate Management Ltd | Administrative & support | 2019 |
| Speak With Jack Ltd | Education | 2021 |
| Spearmansuk Ltd | Professional & scientific | 2024 |
| Specialist HIP & Knee Surgery Ltd | Health & social care | 2024 |
| Specswarehouse Ltd | Wholesale & retail | 2015 |
| Spectra Shopping Ltd | Wholesale & retail | 2018 |