| DR Iseb Limited | Health & social care | 2010 |
| DR James Larkin Ltd | Health & social care | 2013 |
| DR JQ Healthcare Ltd | Health & social care | 2022 |
| DR Lords Limited | Construction | 2023 |
| DR Paredi Medical Services Ltd | Health & social care | 2011 |
| DR RAJ Shah Ltd | Health & social care | 2021 |
| DR RVP Ltd | Health & social care | 2026 |
| DR Victoria Sampson Ltd | Health & social care | 2022 |
| DR. Farah Janmohamed Limited | Health & social care | 2012 |
| DR. Keith Practice Limited | Professional & scientific | 2012 |
| DR10 Consulting Mechanical Ltd | Construction | 2019 |
| DRA Construction Ltd | Construction | 2020 |
| Dragon City (Doncaster) Limited | Administrative & support | 2008 |
| Dragonet Limited | Professional & scientific | 2006 |
| Dragonfangs Limited | Hospitality | 2021 |
| Drainage Flush Limited | Construction | 2026 |
| Drakeglen Limited | Real estate | 1991 |
| Draper Trading Ltd | Financial services | 2020 |
| Dream Hair (UK) Limited | Extraterritorial | 2013 |
| Dream Homes Decoration Ltd | Construction | 2023 |
| Dream Kitchen Ware Limited | Wholesale & retail | 2024 |
| Dream Like Clockwork Films Limited | Other services | 2014 |
| Dream Properties Services Limited | Households | 2024 |
| Dreamgate Limited | Real estate | 2024 |
| Dreamhealth Plus Ltd | Wholesale & retail | 2018 |
| DREAMIN3D Ltd | Manufacturing | 2022 |
| Dreams Global Ltd | Administrative & support | 2017 |
| Dreams to Come Limited | Real estate | 2023 |
| Dreamy Builders Ltd | Construction | 2017 |
| Dresscode Uniforms Ltd. | Manufacturing | 2016 |
| Dreymoor Fertilizers Overseas UK Ltd | Wholesale & retail | 2022 |
| Drip on Demand Ltd | Health & social care | 2025 |
| Drisco Ltd | Real estate | 2019 |
| Drive - on Ltd | Education | 2020 |
| Drive 59 Limited | Administrative & support | 2015 |
| Drive Phase PV Limited | Professional & scientific | 2018 |
| Drive-Mee Ltd | Transport & logistics | 2024 |
| Driveline Autos Limited | Wholesale & retail | 2025 |
| Drivemaster Ltd | Transport & logistics | 2018 |
| Drivesh Ltd | Transport & logistics | 2024 |
| Dromepix Limited | Administrative & support | 2016 |
| Drop Smart UK Ltd | Wholesale & retail | 2025 |
| Drosia Biopharma Consulting Ltd | Professional & scientific | 2024 |
| DRT Signalling Services Ltd | Administrative & support | 2011 |
| DRY Cleaning 2 YOU Limited | Other services | 2000 |
| DRZ Food Ltd | Hospitality | 2024 |
| DS Homeware Ltd | Wholesale & retail | 2023 |
| DSC Inteligence Solutions Limited | Information & communication | 2016 |
| Dsdm Limited | Financial services | 2025 |
| Dseta Consulting Ltd | Transport & logistics | 2026 |
| DSH Design Ltd | Construction | 2024 |
| Dspa Services Limited | Administrative & support | 2006 |
| Dspr UK Abodes Ltd | Real estate | 2026 |
| Dsprlivings Limited | Real estate | 2026 |
| Dsrn Enterprises Ltd | Professional & scientific | 2026 |
| Dubai Shawarma W2 Ltd | Hospitality | 2026 |
| Dubai's Halal Food Ltd | Hospitality | 2025 |
| DUC Performance Limited | Wholesale & retail | 2025 |
| Dudley House Limited | Real estate | 2003 |
| Duet Counselling and Consulting Limited | Health & social care | 2015 |
| Dulce Amor Ltd | Wholesale & retail | 2024 |
| Dumitriu Limited | Construction | 2018 |
| Duncan Consultants Limited | Professional & scientific | 2011 |
| Duncan Kiely Limited | | 1970 |
| Duno & Mahar Limited | Hospitality | 2013 |
| Dunsany Limited | Households | 1973 |
| Dunsham Limited | Real estate | 2009 |
| Dunstan International Ltd | Information & communication | 2021 |
| Dunwood Manor Romsey Limited | Health & social care | 2024 |
| Dunwood Properties Limited | Construction | 2001 |
| Duraggy Global Ltd | Manufacturing | 2019 |
| Duran Fabric Care Ltd | Administrative & support | 2025 |
| Durbano Capital Group Limited | Financial services | 2024 |
| Dutchilon Ltd | Real estate | 2020 |
| DVD Electronics Limited | Wholesale & retail | 2010 |
| Dveltrix Limited | Information & communication | 2025 |
| DVS Foundation | Other services | 2012 |
| DVS Ground Rent Limited | Real estate | 2017 |
| DVS Management Limited | Real estate | 2015 |
| DVS Plumbing and Heating Ltd | Construction | 2021 |
| DVS Property Group Limited | Financial services | 2018 |
| DVS Property Limited | Real estate | 1985 |
| DW BI Ltd | Information & communication | 2010 |
| Dwelldom Limited | Construction | 2025 |
| Dwellsphere Developments Ltd | Construction | 2020 |
| Dwellsphere Ltd | Wholesale & retail | 2020 |
| DWM Group Ltd | Real estate | 2020 |
| Dyad Collective Limited | Information & communication | 2017 |
| Dylan & Co Properties Limited | Real estate | 2018 |
| Dylvi Ltd | Real estate | 2024 |
| Dynalink Ltd | Wholesale & retail | 2014 |
| Dynamic BAG Limited | Wholesale & retail | 2018 |
| Dynamic Consultants (London) Ltd | Professional & scientific | 2020 |
| Dynamic Soft Limited | Information & communication | 2013 |
| Dynamic Software Consulting Ltd | Information & communication | 2019 |
| Dynamics Healthcare Initiatives Ltd | Health & social care | 2023 |
| Dynamiks Ltd | Information & communication | 2018 |
| Dynasty Property Group Ltd | Real estate | 2021 |
| Dysons Group Limited | Real estate | 2016 |
| DZK Logistics Limited | Transport & logistics | 2026 |