| Stone Osmond Limited | Professional & scientific | 1996 |
| Stone Plumbing Plus Limited | Construction | 2024 |
| Stoneham Park Car Parking Limited | Extraterritorial | 2006 |
| Stoneham Park Developments LLP | | 2017 |
| Stonerite Memorials Limited | Other services | 2026 |
| Stones Catering Limited | Hospitality | 2002 |
| Stony Group Ltd | Wholesale & retail | 2022 |
| Storme Inns Limited | Hospitality | 2022 |
| STP Group Limited | Financial services | 2018 |
| STP Trustees Limited | Professional & scientific | 2023 |
| Strandtown Limited | Professional & scientific | 1993 |
| Strategy Innovations Int'L Ltd | Professional & scientific | 2024 |
| Stratino Design Services Limited | Professional & scientific | 2007 |
| Stratprofiling Ltd | Professional & scientific | 2023 |
| Streamii Ltd | Information & communication | 2026 |
| Streamline Power Limited | Administrative & support | 2009 |
| Street Advisory Holdings Ltd | Administrative & support | 2024 |
| Streetfoodz Ltd | Hospitality | 2026 |
| Strengthify Ltd | Professional & scientific | 2023 |
| Stricklands Family Limited | Health & social care | 2012 |
| Structeam Holdings Limited | Financial services | 2013 |
| Structeam Ltd | Construction | 2010 |
| Stuart W Ford Project Management Ltd | Professional & scientific | 2024 |
| Student & Professional Homes Winchester Ltd | Households | 2018 |
| Student Housing (Hampshire) Limited | Real estate | 2005 |
| Student Housing (Holding) Limited | Financial services | 2020 |
| Studfast Equestrian Limited | Manufacturing | 2019 |
| Studio Saar (UK) Ltd | Professional & scientific | 2021 |
| Studiofour Marketing Services Limited | Administrative & support | 2021 |
| Studioyou Limited | Arts & recreation | 2026 |
| Style Improvements Limited | Construction | 1990 |
| STYLELISTICS@357 Limited | Other services | 2014 |
| Stylowa Moda UK Ltd | Wholesale & retail | 2022 |
| Stylowe Buty UK Ltd | Wholesale & retail | 2024 |
| SUB Cooling Ltd | Administrative & support | 2014 |
| SUB Surface Engineering Limited | Manufacturing | 2013 |
| Sugar Hive Ltd | Wholesale & retail | 2025 |
| Sukee Market Limited | Hospitality | 2018 |
| Sukhmani Consultancy Limited | Professional & scientific | 2021 |
| Sukhmani Property Investments Limited | Real estate | 2023 |
| Sullivan 2000 Ltd | Professional & scientific | 2026 |
| Sumerian Ltd | Health & social care | 2026 |
| Summer Island Ltd | Wholesale & retail | 2025 |
| Summerlands Capital Limited | Financial services | 2022 |
| Summit Family Mediation Limited | Professional & scientific | 2019 |
| Summit NW Group Ltd | Financial services | 2026 |
| Summit Property Investments NW Ltd | Real estate | 2026 |
| Sun EYE Care Ltd | Health & social care | 2015 |
| Sunava Tourism Ltd | Hospitality | 2020 |
| Sunder Inc Ltd | Information & communication | 2026 |
| Sunningdale Park Management Limited | Households | 2021 |
| Sunny Lettings Limited | Real estate | 2015 |
| Sunrise Corner Limited | Real estate | 2021 |
| Supermarket Wizard Limited | Information & communication | 2021 |
| Supermassive Games 1 Limited | Information & communication | 2015 |
| Supermassive Games 2 Limited | Information & communication | 2015 |
| Supermassive Games 3 Limited | Information & communication | 2017 |
| Supermassive Games Limited | Information & communication | 2007 |
| Superplain Ltd | Professional & scientific | 2026 |
| Supply Chain Solutions (International) Ltd | Administrative & support | 2015 |
| Supreme Connect Limited | Real estate | 2015 |
| Supreme Logistics Limited | Professional & scientific | 2000 |
| Sure Health & Beauty Limited | Wholesale & retail | 2005 |
| Surefix Interiors Ltd. | Construction | 2018 |
| Sureline Electrical Modules Ltd. | Manufacturing | 2002 |
| Surf Academy UK Ltd | Arts & recreation | 2022 |
| Surf Retreats Ltd | Health & social care | 2024 |
| Surface Dressing Contractors Ltd | Professional & scientific | 2026 |
| Surge Energy Services Ltd | Manufacturing | 2023 |
| Surgery Labs Ltd | Professional & scientific | 2021 |
| Surgimed Academy Limited | Health & social care | 2023 |
| Sustainable Economy Limited | Professional & scientific | 2017 |
| Sustainable Product Group Limited | Extraterritorial | 2018 |
| Sutherland Lettings Limited | Real estate | 2019 |
| Suzie Templeton Limited | Information & communication | 2005 |
| Swan Lake View (Yateley) Limited | Households | 2013 |
| Swat Construction & Installations Ltd | Construction | 2012 |
| Sweet TV Limited | Information & communication | 1989 |
| Swell Electrical Ltd | Construction | 2019 |
| Swellfix UK Limited | Mining & quarrying | 2007 |
| Swetha Priya Services Ltd | Health & social care | 2018 |
| SWF Construction Ltd | Construction | 2019 |
| Swift Build Pro Limited | Construction | 2025 |
| Swift Construction Cost Management Ltd | Professional & scientific | 2017 |
| Swifter Limited | Information & communication | 2017 |
| Swifts Property Limited | Real estate | 1999 |
| Swingfire Solutions LLP | | 2013 |
| Swoop Digital Ltd | Professional & scientific | 2025 |
| SX6 Limited | Information & communication | 2011 |
| Syah Limited | Wholesale & retail | 2026 |
| Sybaris Limited | Information & communication | 1999 |
| Sylva Construction Ltd | Construction | 2021 |
| Sylva Investments Ltd | Real estate | 2022 |
| Sylva Trading Ltd | Wholesale & retail | 2021 |
| Symbiotai Risk Ltd | Information & communication | 2026 |
| Symmons Healthcare Ltd | Health & social care | 2024 |
| Symss Solutions Ltd | Professional & scientific | 2017 |
| Synergy RX Limited | Wholesale & retail | 2024 |
| Synlace Ltd | Information & communication | 2025 |
| Synote Limited | Information & communication | 2016 |