| DE Jure Skin Ltd | Wholesale & retail | 2023 |
| DE-RAIL80CHAIN Limited | Professional & scientific | 2025 |
| Dear Green Holdings Ltd | Real estate | 2026 |
| Decades HR Consultancy Ltd | Administrative & support | 2025 |
| DEE Beauty Salon Ltd | Other services | 2025 |
| DEE Gee's Limited | Other services | 2023 |
| Dee's Cleaning Services Limited | Administrative & support | 2019 |
| Deep Illumination Consulting Ltd | Professional & scientific | 2025 |
| Deep Illumination Ltd | Professional & scientific | 2021 |
| Deep Sea Atlantic (UK) Ltd | Mining & quarrying | 2017 |
| Deep Sea RIG (UK) Ltd | Mining & quarrying | 2024 |
| Deep Sea Stavanger (UK) Ltd | Mining & quarrying | 2017 |
| Deep South Media Holdings Limited | Financial services | 2022 |
| Deep South Media Limited | Professional & scientific | 1998 |
| Defcom Ltd | Professional & scientific | 2014 |
| Definitions Property Care Limited | Construction | 2014 |
| Deii-Vamee Properties Ltd | Real estate | 2022 |
| Deinuk Limited | Administrative & support | 2018 |
| Dejero Europe Limited | Wholesale & retail | 2013 |
| DEK Graphics & Print Limited | Administrative & support | 2008 |
| Delhi Properties Limited | Real estate | 2024 |
| Dellans Farm Ltd | Construction | 2023 |
| Dellune Engineers Limited | Real estate | 1975 |
| Delta Global Consultants Limited | Professional & scientific | 2007 |
| Delta Global Consulting Ltd | Professional & scientific | 2008 |
| Deltax UK Limited | Professional & scientific | 2026 |
| Demeflex Fitness Limited | Arts & recreation | 2021 |
| Dendec Limited | Health & social care | 2016 |
| Denison Nunn Limited | Administrative & support | 2024 |
| Dental&Beauty Ltd | Administrative & support | 2021 |
| Dentec Electrical Limited | Construction | 2026 |
| Dentsit Limited | Health & social care | 2023 |
| Denzil Estates Limited | Real estate | 2022 |
| Derek Osgood Limited | Wholesale & retail | 2018 |
| Derisley Close Management Limited | Households | 2007 |
| Desborough Property Investments Limited | Real estate | 2017 |
| Design and Build Technical Limited | Professional & scientific | 2016 |
| Designscapes (Southwest) Ltd | Administrative & support | 2008 |
| Dessex Limited | Professional & scientific | 2025 |
| Dessy's Therapy Limited | Other services | 2024 |
| Desty Marine Hamble Limited | Manufacturing | 2018 |
| Development Engineering Limited | Construction | 2017 |
| DFN Engineering Consultancy Limited | Wholesale & retail | 2025 |
| DG Poole Property Limited | Real estate | 2016 |
| DGI Fire Risks Ltd | Administrative & support | 2023 |
| DGN1618 Limited | Hospitality | 2024 |
| DH Southampton Limited | Professional & scientific | 2015 |
| Dhillon Consultancy Ltd | Information & communication | 2026 |
| Dhillon Motor Holdings Ltd | Wholesale & retail | 2018 |
| Dhillon Property Assets Ltd | Real estate | 2025 |
| Dhrisha Properties Ltd | Real estate | 2025 |
| Dhrisha Property Group Ltd | Real estate | 2026 |
| Dhwani Holdings Ltd | Financial services | 2026 |
| DI Carlo Group Ltd | Hospitality | 2026 |
| DI Carlo Lymington Ltd | Hospitality | 2026 |
| Diallo Healthcare Limited | Extraterritorial | 2024 |
| Diamond Gaming Computers Ltd | Wholesale & retail | 2020 |
| Diamond Paintings Limited | Extraterritorial | 2014 |
| Diamond Window Tinting Ltd | Wholesale & retail | 2017 |
| Dianoia Holdings Ltd | Financial services | 2024 |
| Dianoia Services Limited | Information & communication | 2011 |
| Dibden Purlieu Motors Limited | Wholesale & retail | 1979 |
| Dickens Limited | Extraterritorial | 1983 |
| Diclig Ltd | Households | 2024 |
| Different Journey Limited | Administrative & support | 2017 |
| Diggerfix Ltd | Professional & scientific | 2025 |
| Digicomnest Ltd | Wholesale & retail | 2025 |
| Digital 10 Ltd | Professional & scientific | 2009 |
| Digital Assess Software Limited | Education | 2016 |
| Digital Narrative Care Ltd | Professional & scientific | 2026 |
| Digital Plant POT Ltd | Professional & scientific | 2024 |
| Digital Signbox Limited | Extraterritorial | 2011 |
| Digital Templating Services Limited | Construction | 2013 |
| Diguru Limited | Manufacturing | 2009 |
| Digweed Landscapes Ltd | Administrative & support | 2024 |
| Diharris Geotechnics Limited | Construction | 2009 |
| Dillbird Limited | Wholesale & retail | 2018 |
| Dinkspace Events Ltd | Arts & recreation | 2026 |
| Dinkspace Group Ltd | Arts & recreation | 2026 |
| Direct Advocacy Group Ltd | Information & communication | 2024 |
| Directdrains Ltd | Water & waste | 2018 |
| Dirty Box Promotions Limited | Arts & recreation | 2007 |
| Distinct Look Ltd | Wholesale & retail | 2014 |
| Diverso Accountants Limited | Professional & scientific | 2015 |
| Diving Equipment Services Limited | Manufacturing | 1998 |
| DJ21 Ltd | Real estate | 2021 |
| DJA Counselling Ltd | Health & social care | 2020 |
| Djare Group Ltd | Real estate | 2025 |
| DJB Building Winchester Limited | Construction | 2009 |
| DJG Limited | Construction | 2025 |
| DJJ Toal Engineering Ltd | Professional & scientific | 2025 |
| DJL Marine Projects Limited | Professional & scientific | 2018 |
| DK Coaching Limited | Education | 2026 |
| DK Lawn & Order Gardening Services Ltd | Administrative & support | 2018 |
| Dk&R Properties Management Company Ltd | Households | 2025 |
| DKY. Limited | Construction | 2015 |
| DLE Daylight Express Ltd | Health & social care | 2019 |
| Dlissner Ltd | Construction | 2024 |
| Dlsvaleting Ltd | Administrative & support | 2023 |
| DM Audiolab Limited | Information & communication | 2025 |