| Queenx Nails Ltd | Other services | 2025 |
| Quest Employment Limited | Administrative & support | 2005 |
| Questex Limited | Households | 1987 |
| Quiet Courage Counselling CIC | Education | 2026 |
| Quik Ebooks Limited | Other services | 2011 |
| Quill Property Services Ltd | Households | 2019 |
| Quillski Ltd | Extraterritorial | 2016 |
| Quin Electrical Ltd | Construction | 2024 |
| Quinn the FOX Limited | Extraterritorial | 2017 |
| Quinnell Drive (Hailsham) Limited | Households | 2012 |
| QW Projects Limited | Construction | 2024 |
| Qwaly Ltd | Information & communication | 2020 |
| Qyyl Limited | Health & social care | 2026 |
| R & a Trading Limited | Wholesale & retail | 2024 |
| R & K Northampton Limited | Wholesale & retail | 2014 |
| R & L Tanning Limited | Other services | 2018 |
| R & R Property Maintenance Services Ltd | Construction | 2020 |
| R a Premium Property Ltd | Real estate | 2024 |
| R and K Livestock Service Ltd | Agriculture & fishing | 2011 |
| R G C Endodontics Limited | Health & social care | 2020 |
| R J Morley Limited | Professional & scientific | 2010 |
| R N Electrical & Signalling Installations Ltd | Construction | 2007 |
| R S Dental Limited | Health & social care | 2013 |
| R S Fine Art LLP | | 2016 |
| R S R Refurbishments Limited | Construction | 1998 |
| R&C Cars Limited | Wholesale & retail | 2010 |
| R&H Medical Limited | Health & social care | 2022 |
| R&J Halal Ltd | Wholesale & retail | 2026 |
| R&J Plastering Limited | Construction | 2022 |
| R&J Vision, Hearing and Balance Limited | Health & social care | 2014 |
| R&R Structural Engineers Ltd | Construction | 2018 |
| R. R. Developments (LR) Ltd | Real estate | 2025 |
| R. R. Developments (SR) Limited | Construction | 2021 |
| R. R. Developments Limited | Construction | 2003 |
| R. R. Hyde Road Ltd | Construction | 2018 |
| R.C. Swim LAB Ltd | Arts & recreation | 2025 |
| R.Collins Builders Limited | Construction | 2003 |
| R.D.J.L Limited | Financial services | 2011 |
| R.E.M. Property Holdings Limited | Real estate | 2009 |
| R.E.M. Rentals Limited | Real estate | 2024 |
| R.R. Developments (KD) Ltd | Real estate | 2023 |
| R2 Property Group Limited | Real estate | 2019 |
| R8G UK Limited | Information & communication | 2020 |
| RA RGN Ltd | Health & social care | 2023 |
| Racetime.Gg Limited | Arts & recreation | 2020 |
| Racine Advisory Limited | Professional & scientific | 2010 |
| Rada Media Ltd | Professional & scientific | 2020 |
| Radiology JAM Limited | Health & social care | 2026 |
| Radium Audio Ltd | Administrative & support | 2007 |
| Radpark Ltd | Professional & scientific | 2023 |
| Rafada Ltd | Real estate | 2025 |
| RAH Payments Ltd | Information & communication | 2020 |
| Raicon Properties Limited | Administrative & support | 1958 |
| Railway Renovations Ltd | Real estate | 2021 |
| Railway Retreats Limited | Hospitality | 2016 |
| Rainbow Cleaners Ltd | Other services | 2018 |
| Rainbow YH Business Ltd | Real estate | 2026 |
| Raird Limited | Health & social care | 2019 |
| Ramos Grill Ltd | Hospitality | 2018 |
| Rana Risk Management Ltd | Administrative & support | 2008 |
| Rance Transport Ltd | Transport & logistics | 2025 |
| Randalls Auto's Limited | Wholesale & retail | 2018 |
| Rangemore Close Eastbourne Limited | Households | 2014 |
| Ranjbar Holdings Ltd | Real estate | 2025 |
| Ranworth Residents Association Limited | Real estate | 1971 |
| Rapid Asset Solutions Ltd | Wholesale & retail | 2026 |
| Rapisarda Properties Limited | Real estate | 2024 |
| Rare Form Services Limited | Administrative & support | 2026 |
| Rasichka Limited | Health & social care | 2009 |
| Rathod Holdings Ltd | Financial services | 2020 |
| Ratton Pantry Ltd | Wholesale & retail | 2021 |
| Ratton Village Flats Limited | Households | 1997 |
| Ratton Village Residents' Association Limited | Households | 1972 |
| Ravelston Grange RTM Company Limited | Households | 2023 |
| Ravens Croft (Eastbourne) Residents Company Limited | Households | 1972 |
| Ravensbury Court (Carshalton)Residents' Association Limited | Households | 1963 |
| Ravi Chauhan Ltd | Health & social care | 2024 |
| Ravince Health Ltd | Financial services | 2019 |
| RAW Tech Solutions Limited | Information & communication | 2011 |
| RAW Tours Ltd | Administrative & support | 2022 |
| RAY Shilling Ltd | Financial services | 2009 |
| Rayner Property Services (Eastbourne) Limited | Real estate | 1980 |
| Razvan Building Services Ltd | Construction | 2015 |
| RB Investment Holdings Limited | Financial services | 2023 |
| RB Mechanical Management Limited | Construction | 2024 |
| RB Wine and Agricultural Services Ltd | Manufacturing | 2025 |
| RBA Developments Limited | Construction | 2018 |
| Rbabm Medical Limited | Health & social care | 2017 |
| Rbec Ltd | Construction | 2021 |
| RC Commerce Ltd | Wholesale & retail | 2023 |
| Rcas Holdings Limited | Financial services | 2025 |
| Rccg Grace Haven Chapel East Sussex Ltd | Other services | 2023 |
| Rcjl Holdings Limited | Real estate | 2024 |
| RCM Broking Limited | Financial services | 2018 |
| RCS Dentistry Ltd | Health & social care | 2023 |
| RD & RS Medical Services Limited | Health & social care | 2018 |
| RD Enterprises Limited | Health & social care | 2023 |
| RDK Dental Ltd | Health & social care | 2022 |
| RDS Electrical Ltd | Construction | 2015 |
| RDS Shipping Ltd | Transport & logistics | 2020 |