| Newhaven Football Club (Casc) Limited | Arts & recreation | 2016 |
| Newhaven Storage Ltd | Real estate | 2025 |
| Newling Consulting Ltd | Professional & scientific | 2024 |
| News Team Limited | Extraterritorial | 1998 |
| Newstead Villas Management Company Limited | Households | 2025 |
| Newstrade Marketing Limited | Professional & scientific | 2003 |
| Nexdesk Limited | Information & communication | 2026 |
| Next GEN CV Ltd | Administrative & support | 2020 |
| Next GEN Vehicle Sales Limited | Wholesale & retail | 2025 |
| Next Stage Healthcare Ltd | Health & social care | 2015 |
| Nextdoor Eastbourne Ltd | Hospitality | 2021 |
| Nextsphere Ltd | Wholesale & retail | 2025 |
| Nexus (Southern) Limited | Transport & logistics | 2025 |
| Nexus Power Systems Limited | Professional & scientific | 2026 |
| NFD Logic Systems Ltd | Information & communication | 2026 |
| Nfsg Ltd. | Manufacturing | 2014 |
| NHC Investments Limited | Real estate | 2019 |
| NIALA2 Limited | Administrative & support | 2018 |
| NIC Preece Designs Ltd | Professional & scientific | 2021 |
| Nice N' Clean Ltd | Construction | 2025 |
| Nicermer Hotels Limited | Hospitality | 2026 |
| Nick Stubbs Limited | Construction | 2016 |
| Nick Trans 28 Ltd | Transport & logistics | 2024 |
| Nick Violaris Ltd. | Health & social care | 2002 |
| Nick Webster Limited | Health & social care | 2019 |
| Nicki Tanner Consulting Limited | Professional & scientific | 2006 |
| Nicola James Communications Ltd | Arts & recreation | 2008 |
| Nicwebb Ltd | Arts & recreation | 2023 |
| Nieuway Limited | Professional & scientific | 2018 |
| Nigel's Choice Ltd | Wholesale & retail | 2025 |
| Nightingale F Limited | Public administration | 2024 |
| Nightingale Kennels Limited | Agriculture & fishing | 2024 |
| Nights Music Entertainment Ltd | Hospitality | 2020 |
| Nikhil N Patel Limited | Health & social care | 2025 |
| Nikhil Patel Limited | Health & social care | 2010 |
| Nikki’S Clean Cleaners Ltd | Administrative & support | 2025 |
| Nila DEV Ltd | Hospitality | 2026 |
| Nilkanthraj Ltd | Wholesale & retail | 2022 |
| Nima Coffee Trading Limited | Hospitality | 2012 |
| Nimble Technology Services Limited | Information & communication | 2022 |
| Nimbyte Limited | Information & communication | 2005 |
| Nine Finger Games Ltd | Information & communication | 2022 |
| Nine Five Design Ltd | Manufacturing | 2025 |
| Nineteen Upper Avenue Limited | Households | 1985 |
| Ninkaci Limited | Hospitality | 2020 |
| Ninolac. International S.A Limited | Information & communication | 2026 |
| Nisa Hair Limited | Other services | 2025 |
| Nitty Gritty Creative Ltd | Professional & scientific | 2006 |
| Nive Enterprise Ltd | Wholesale & retail | 2018 |
| Nixan Carpentry & Refurbs Ltd | Construction | 2023 |
| Nixon & Jarvis Limited | Other services | 2013 |
| Nixon Consulting Limited | Manufacturing | 2022 |
| NKH Limited | Health & social care | 2010 |
| Nkj-Tech Ltd | Information & communication | 2018 |
| NKN Medical Ltd | Health & social care | 2022 |
| NN Dental Limited | Health & social care | 2021 |
| NO Bones About IT Fishmongers Ltd | Wholesale & retail | 2020 |
| NO One Internet Ltd | Information & communication | 2020 |
| NO Stone Unturned Fundraising Limited | Professional & scientific | 2013 |
| NO Way Limited | Wholesale & retail | 2011 |
| Noakes Heathfield Limited | Hospitality | 2022 |
| Noble & Barker Ltd | Health & social care | 2025 |
| Noble & Cindy Ltd | Health & social care | 2025 |
| NODDYSM8INVESTMENT’S Ltd | Administrative & support | 2022 |
| Nola (Hove) Limited | Hospitality | 2012 |
| Nomad's Nectar Ltd | Manufacturing | 2024 |
| Nomx Ltd | Information & communication | 2021 |
| Noor Chouhan Limited | Other services | 2024 |
| Nope Distribution Ltd | Wholesale & retail | 2026 |
| Norfolk House Freeholders Ltd | Real estate | 2005 |
| Norman Wakabayashi Ltd | Manufacturing | 2018 |
| Normanhurst (Eastbourne) Limited | Professional & scientific | 2005 |
| North Laine Hair Company LLP | | 2012 |
| North Laine Hair Retail Ltd | Wholesale & retail | 2022 |
| Northall CPC Limited | Arts & recreation | 2014 |
| Northbourne Seventy Three Limited | Manufacturing | 2007 |
| Northbridge Capital Group Ltd | Wholesale & retail | 2026 |
| Northern Medical Services Ltd | Health & social care | 2019 |
| Northern Property Select Ltd | Real estate | 2022 |
| Northiam Dental Limited | Health & social care | 2026 |
| Northisfam Holding Company Limited | Professional & scientific | 2022 |
| Northwood (Eastbourne) Limited | Real estate | 2007 |
| Noshers Limited | Construction | 2004 |
| Nosta Bella Vista Limited | Extraterritorial | 1995 |
| NOT Another Drama Group C.I.C. | Education | 2025 |
| Notec Ltd | Water & waste | 2015 |
| Notloud Lettings Limited | Real estate | 2025 |
| Nova BEE Ltd | Professional & scientific | 2026 |
| Nova Eastbourne Limited | Hospitality | 2026 |
| Nova Media Collective Ltd | Professional & scientific | 2024 |
| Nova Renewables Limited | Construction | 2011 |
| Novodente Ltd | Financial services | 2020 |
| NOW Vintage Limited | Wholesale & retail | 2025 |
| Nowbelieve | Arts & recreation | 2009 |
| Npdp Limited | Health & social care | 2021 |
| Nped Services Ltd | Information & communication | 2022 |
| NPI Engineering Ltd | Professional & scientific | 2012 |
| NPS Recruitment Limited | Education | 2016 |
| NRG Card Payment Services Ltd | Administrative & support | 2024 |
| NRG Commercial Finance Limited | Financial services | 2013 |