| Ralph Hodge Associates Limited | Administrative & support | 1993 |
| Ranalah Moulds Ltd | Extraterritorial | 2004 |
| Rand Reclamation Ltd | Wholesale & retail | 2000 |
| Randolph Villas Limited | Households | 1999 |
| Ranmore Service and Engineering (Rs&E) Ltd | Wholesale & retail | 2021 |
| RAO E-Com Limited | Wholesale & retail | 2025 |
| Rashsound Limited | Information & communication | 2003 |
| Ratton Croft Management Limited | Households | 1958 |
| Raven Team Limited | Administrative & support | 2007 |
| RAY Hacker Autos Limited | Wholesale & retail | 2003 |
| Raygone Limited | Construction | 2006 |
| Raymond Beaumont Limited | Real estate | 2007 |
| Raystede Animal Services Limited | Other services | 1996 |
| RBE Associates Limited | Health & social care | 2011 |
| RBH Services Limited | Water & waste | 2003 |
| RBS Building Services Limited | Administrative & support | 2002 |
| Read Print (South Coast) Limited | Professional & scientific | 1984 |
| Readhowyouwant.Com Limited | Information & communication | 1995 |
| Rebar South Limited | Construction | 2006 |
| Rebound Care and Support Ltd | Health & social care | 2025 |
| Red Card Publishing Limited | Information & communication | 1995 |
| Refernet Limited | Extraterritorial | 2008 |
| Reflex Racing G.B. Limited | Administrative & support | 2005 |
| Reframe Limited | Professional & scientific | 2000 |
| Regency Court Residents (Eastbourne) Limited | Households | 1965 |
| Regency Properties (Brighton) Limited | Real estate | 2006 |
| Regency Restaurant (Brighton) Limited | Hospitality | 2003 |
| Relax Inn Brighton Limited | Hospitality | 2012 |
| Relaymajor Limited | Wholesale & retail | 1991 |
| Religion Limited | Wholesale & retail | 1994 |
| Rely Consulting Ltd | Information & communication | 2003 |
| Retcorse Property Co.Limited | Construction | 1958 |
| Rhino Asphalt Solutions Limited | Construction | 2000 |
| Rhino Marketing Limited | Financial services | 2002 |
| Richard Brett Kitchens Limited | Construction | 2003 |
| Richard Dawson Limited | Professional & scientific | 1985 |
| Richard Durrant Limited | Arts & recreation | 2002 |
| Richlife Limited | Wholesale & retail | 2006 |
| Ricochet Signs Ltd | Administrative & support | 2003 |
| Ridgewood Construction Limited | | 1987 |
| Ridgewood Estates Limited | Real estate | 2005 |
| Rightjob.Co.Uk Limited | Professional & scientific | 2007 |
| Ringmark Limited | Extraterritorial | 2003 |
| Riversdale Fencing and Landscaping Limited | Administrative & support | 2007 |
| Riverside Flowers Lewes Limited | Wholesale & retail | 2003 |
| RME Arts and Education Limited | Education | 2021 |
| Robert Smith Video Repairs Limited | Manufacturing | 2003 |
| Robin Clay Limited | Professional & scientific | 1974 |
| Rochford Project Services Limited | Other services | 1995 |
| Rockspey Limited | Households | 2002 |
| Roedean School Enterprises Limited | Hospitality | 1994 |
| Rogman Butchers Limited | Wholesale & retail | 2003 |
| Roke Associates Limited | Information & communication | 1985 |
| Rolaren Investments Limited | Real estate | 2022 |
| Rosan & Company Limited | Professional & scientific | 2012 |
| Rose Properties Developments Ltd | Professional & scientific | 2003 |
| Roselands Heating Limited | Construction | 1986 |
| Round Wood of Mayfield Limited | Manufacturing | 2009 |
| Rowan Tree Surgery Limited | Agriculture & fishing | 2008 |
| RR Holdings Limited | Wholesale & retail | 2004 |
| RR Properties 2006 Limited | Real estate | 2006 |
| Ruby's Bakery Limited | Manufacturing | 2007 |
| Rush, Witt & Wilson (Bexhill) Limited | Professional & scientific | 2004 |
| Rush, Witt & Wilson (Tenterden) Limited | Real estate | 2007 |
| Rush, Witt & Wilson Limited | Real estate | 2004 |
| Rushlake Consulting Limited | Professional & scientific | 1998 |
| Russell Bourne Kitchens Limited | | 1978 |
| Russell Norman Fencing Ltd | Construction | 2005 |
| Rustington Court Management Company Limited | Households | 1977 |
| RWC Technology Limited | Manufacturing | 1991 |
| RYE Cleaning Services Limited | Other services | 1995 |
| RYE Fishing, Fuel and Flake Ice Company Limited | Wholesale & retail | 1996 |
| RYE Hire Limited | Wholesale & retail | 2005 |
| RYE Pottery Limited | Manufacturing | 1971 |
| RYE Watersports Limited | Arts & recreation | 2003 |
| RYE, Winchelsea and District Memorial Hospital Limited | Health & social care | 1992 |
| Ryeford Installations Limited | | 1989 |
| S & T Windows Limited | Construction | 1980 |
| S B Financial Solutions Limited | Administrative & support | 2006 |
| S C F Associates Limited | Information & communication | 1998 |
| S D Newbury Limited | Construction | 2005 |
| S E Partnership Limited | Real estate | 2003 |
| S P C Management Consulting Ltd | Professional & scientific | 2008 |
| S R Orwin Limited | Professional & scientific | 2004 |
| S. Finch Jewellers Limited | Wholesale & retail | 2002 |
| S.E.S Plumbing & Heating Limited | Wholesale & retail | 2003 |
| S.J. Hampton Removals Ltd. | Transport & logistics | 2007 |
| S.M.D. Formwork Limited | Construction | 1999 |
| S.R. Jenner Limited | Wholesale & retail | 1994 |
| Saadia Ltd | Wholesale & retail | 2005 |
| Saam Enterprises Ltd | Wholesale & retail | 2017 |
| Sabre Controls Limited | Manufacturing | 1997 |
| Sabre Mechanical Services Limited | Construction | 2007 |
| SAC Properties Ltd | Real estate | 2007 |
| Sachdill Investments Limited | Real estate | 2002 |
| Safehaven Properties (Sussex) Limited | Real estate | 2003 |
| Sagan Enterprises Limited | Professional & scientific | 1999 |
| Salehurst Property Company Limited | Real estate | 2005 |
| Sales to Success Ltd. | Information & communication | 2001 |
| Salisbury Construction Services Limited | Construction | 2003 |