| Safaz Properties Limited | Real estate | 2025 |
| Safi Properties Ltd | Real estate | 2022 |
| Sakeena Asset Group Ltd | Wholesale & retail | 2025 |
| Sales CL Ltd | Professional & scientific | 2025 |
| Sales Hawk Ltd | Professional & scientific | 2026 |
| Salisys Consulting Limited | Information & communication | 2023 |
| Sana Fatima Ltd | Wholesale & retail | 2025 |
| Sanscence Limited | Other services | 2025 |
| Sarime Ltd | Households | 2024 |
| Save on Tools Limited | Wholesale & retail | 2025 |
| Savoir Estates Limited | Real estate | 2018 |
| Savoir Telecom Limited | Information & communication | 2019 |
| Sayd Ltd | Transport & logistics | 2025 |
| Schenvy Ltd | Administrative & support | 2026 |
| Scutify Group Ltd | Wholesale & retail | 2025 |
| Secretary & Corporate Support Ltd | Financial services | 2025 |
| Secure Hosted Solutions Limited | Extraterritorial | 2014 |
| Shapes & Sizes Franchise Ltd | Administrative & support | 2026 |
| Shapes & Sizes Limited | Professional & scientific | 2025 |
| Sharif Trading Limited | Wholesale & retail | 2024 |
| Sharingang Ltd | Information & communication | 2026 |
| Shipsmart Europe Ltd | Transport & logistics | 2021 |
| Shozali Ltd | Hospitality | 2025 |
| Sidebottom Properties (Hyde) Limited | Construction | 2019 |
| Sifer Marketing Ltd | Professional & scientific | 2020 |
| Simplivio Ltd | Wholesale & retail | 2025 |
| Sisqual Workforce Management Ltd | Information & communication | 2016 |
| SK Academy Dance Limited | Education | 2022 |
| SK Driveway Solutions Ltd | Construction | 2022 |
| SK Refurb and Lettings Ltd | Construction | 2026 |
| SK16 Dunkinfield Store Limited | Wholesale & retail | 2026 |
| SK16 Store Limited | Wholesale & retail | 2025 |
| Small Acres Limited | Extraterritorial | 2023 |
| Smart Link MCR Ltd | Wholesale & retail | 2023 |
| Solideals Ltd | Wholesale & retail | 2025 |
| Sonia 786 Limited | Wholesale & retail | 2020 |
| Sorella Property Ltd | Real estate | 2024 |
| Sound Insight Ltd | Manufacturing | 2002 |
| Spanish Villa Rentals Limited | Administrative & support | 2016 |
| Special Piping Materials (Holdings) Limited | Wholesale & retail | 2013 |
| Specialised Transport Solutions Limited | Wholesale & retail | 2014 |
| Specialist Valuation Services Limited | Professional & scientific | 1996 |
| Specialist Wiring Solutions Ltd | Construction | 2012 |
| Spirelle Properties Ltd | Real estate | 2025 |
| SPM Carpentry Limited | Construction | 2025 |
| Sports 4 Profit Limited | Wholesale & retail | 2025 |
| Sprintshift NW Limited | Transport & logistics | 2025 |
| Squashedapple Limited | Professional & scientific | 2010 |
| Star Vapes Ltd | Wholesale & retail | 2022 |
| Stephanie Properties Ltd | Real estate | 2022 |
| Stickers Planet Ltd | Manufacturing | 2014 |
| Strawberry Construction Ltd | Construction | 2006 |
| Strawberry Kitchens Ltd | Other services | 2005 |
| STS Fleet Care Ltd | Wholesale & retail | 2025 |
| STS Racing Ltd | Arts & recreation | 2026 |
| STS Roadside & Recovery Ltd | Wholesale & retail | 2025 |
| Sulafe Limited | Health & social care | 2023 |
| Sun & Pilates Ltd | Wholesale & retail | 2026 |
| Supaglaze Ltd | Manufacturing | 2007 |
| SYP Technologies Ltd | Professional & scientific | 2022 |
| Tameside Boiler Repair Ltd | Construction | 2020 |
| Tameside Community Computers CIC | Other services | 2022 |
| Tameside Glass Racks Limited | Manufacturing | 2004 |
| Tameside Indoor Golf Ltd | Arts & recreation | 2023 |
| Taylormade Joinery and Partitioning Ltd | Construction | 2021 |
| TD Coaching Ltd | Professional & scientific | 2026 |
| Tec-It-Out Ltd | Wholesale & retail | 2019 |
| Technical Engineering Design Solutions Ltd | Professional & scientific | 2016 |
| Technical Rescue Training UK Limited | Public administration | 2014 |
| Teds (Electrical) Ltd | Construction | 2012 |
| Teds (Energy) Ltd | Professional & scientific | 2016 |
| Teds (Maintenance) Ltd | Professional & scientific | 2016 |
| TEN2ONE Limited | Professional & scientific | 2008 |
| TG Transport (NW) Ltd | Transport & logistics | 2024 |
| THE Artificers Forge Ltd | Manufacturing | 2020 |
| THE Barn by Tiberius Tudor Ltd | Professional & scientific | 2026 |
| THE Bread Story Ltd | Manufacturing | 2022 |
| THE Cheshire Outhouse Ltd | Construction | 2022 |
| THE DOT Connecting Group Limited | Financial services | 2020 |
| THE Full Spectrum Centre Limited | Other services | 2016 |
| THE Giftlocker Limited | Manufacturing | 2026 |
| THE Good Dog Company N.W Ltd | Wholesale & retail | 2026 |
| THE Joinery Consultant Ltd | Manufacturing | 2024 |
| THE Label Company (T.L.C.) Limited | Manufacturing | 2006 |
| THE Lodge Hotel Limited | Hospitality | 2019 |
| THE Office Supermarket Ltd | Wholesale & retail | 2026 |
| THE Rubber Plantation Ltd | Wholesale & retail | 2014 |
| THE Rubbish Removers Ltd | Water & waste | 2020 |
| THE Rubbish Removers Property Limited | Real estate | 2024 |
| THE Secret Garden Drinks Limited | Wholesale & retail | 2023 |
| Thirsty Soft Drinks Ltd | Manufacturing | 2007 |
| This One Here Ltd | Information & communication | 2026 |
| Thrive Social Ltd | Health & social care | 2022 |
| Thyme to EAT Ltd | Extraterritorial | 2022 |
| Tibard (EOT) Limited | Professional & scientific | 2024 |
| Tibard Limited | Manufacturing | 1979 |
| Tiberius Solutions Ltd | Other services | 2016 |
| TKR Enterprises Ltd | Wholesale & retail | 2025 |
| TM Asbestos Consultancy Limited | Construction | 2022 |
| TMS Electrics Limited | Construction | 2022 |