| Equiture Limited | Wholesale & retail | 2015 |
| Equitus Consultancy Ltd | Professional & scientific | 2014 |
| Erclang Limited | Information & communication | 2013 |
| Erdington Autobodies Limited | Wholesale & retail | 2015 |
| Erdm Properties Ltd | Real estate | 2026 |
| Ergys Delivery Limited | Transport & logistics | 2024 |
| Eric Walker & SON Limited | Construction | 1963 |
| Ericsons Construction Limited | Construction | 2008 |
| Eris Digital Ltd | Professional & scientific | 2025 |
| Eroneteam Ltd | Wholesale & retail | 2018 |
| Escalar Access Ltd | Wholesale & retail | 2025 |
| Esmar Consultancy Limited | Professional & scientific | 2013 |
| ESN (Building) Limited | Construction | 2026 |
| ESQ Clothing Ltd | Wholesale & retail | 2017 |
| Ess.P.H. Limited | Professional & scientific | 2014 |
| ESSENTIALS247 Ltd | Wholesale & retail | 2025 |
| Estadel Services Limited | Health & social care | 2015 |
| Etheridge Consulting Ltd | Other services | 2020 |
| ETW Holdings Ltd | Wholesale & retail | 2024 |
| Euken Albert Palmer Limited | Extraterritorial | 2021 |
| Eureka Safety UK Ltd | Manufacturing | 2021 |
| Eurocab Transfers and Travel Limited | Transport & logistics | 2024 |
| Eurocom Building Services Ltd | Administrative & support | 2017 |
| Eurocom Group Limited | Financial services | 2021 |
| Eurocraft Technologies Limited | Manufacturing | 2012 |
| Euroequip Ltd | Manufacturing | 2013 |
| Euroequip Supplies Ltd | Manufacturing | 2020 |
| Europa Mini Market Ltd | Hospitality | 2020 |
| European Underwriting Agencies Limited | Professional & scientific | 1999 |
| Eurotech Supplies Limited | Manufacturing | 1998 |
| EVA & Brother's Global Ltd | Other services | 2018 |
| Evancoza Ltd | Real estate | 2022 |
| Evangelist Padzarondora Ltd | Health & social care | 2022 |
| Evanie JON Hairdressing Ltd | Other services | 2013 |
| Evans & White Limited | Manufacturing | 1941 |
| Evans & White Manufacturing Limited | Manufacturing | 2000 |
| Evans Scaffolding & Netting Services Limited | Construction | 2013 |
| Evans Web Solutions Ltd | Information & communication | 2008 |
| Event Fest Pro Limited | Hospitality | 2018 |
| Events and Venues Security Company Ltd. | Administrative & support | 2017 |
| Eventswise Ltd | Hospitality | 2022 |
| Evergreen Locums Ltd | Health & social care | 2011 |
| Evolve Home Care Limited | Health & social care | 2019 |
| Evowell Ltd | Wholesale & retail | 2025 |
| Ewale Ecommerce Limited | Wholesale & retail | 2022 |
| Eway Property Limited | Wholesale & retail | 2019 |
| EWS Holdings and Investments Ltd | Financial services | 2025 |
| Excalibur Hygiene Limited | Wholesale & retail | 1991 |
| Excalibur Investigations Limited | Professional & scientific | 2002 |
| Excel Metals (UK) Ltd | Wholesale & retail | 2024 |
| Excelsior Panelling Systems Ltd | Manufacturing | 1978 |
| Exeon Construction Limited | Construction | 2018 |
| Exercise Rehabilitation Association Limited | Arts & recreation | 1986 |
| Exonea Health Ltd | Other services | 2021 |
| Experiential Hypnosis Ltd | Health & social care | 2011 |
| Expert PUB Holdings Ltd | Financial services | 2020 |
| Expial Atrocious Ltd | Arts & recreation | 2023 |
| Express Cleaning Supplies Limited | Wholesale & retail | 1991 |
| Extra Mega Bargains Ltd | Wholesale & retail | 2022 |
| Extra Space Interiors Ltd | Construction | 2018 |
| EYA Design Ltd | Wholesale & retail | 2016 |
| EYE Health Clinic Ltd | Wholesale & retail | 2015 |
| Eyedeal Eyecare Limited | Health & social care | 2011 |
| Eyedeal Opticians Limited | Health & social care | 2003 |
| Eyrie Developments Ltd | Real estate | 2021 |
| EZ Hire a Car Ltd | Administrative & support | 2025 |
| EZ Restoration and Cleaning Ltd | Other services | 2015 |
| Ezekiels Care Ltd | Health & social care | 2022 |
| Ezura Healthcare Limited | Administrative & support | 2024 |
| Ezura Stays Limited | Real estate | 2026 |
| F & D Trading Ltd | Financial services | 2024 |
| F & J Estates Limited | Construction | 2020 |
| F & S Enterprises Ltd | Wholesale & retail | 2024 |
| F & S Ltd | Hospitality | 2019 |
| F W Taylor & SON Plant Hire Ltd | Other services | 2003 |
| F&W Properties Ltd | Real estate | 2020 |
| F.& L.Adams(Pedmore)Limited | Real estate | 1959 |
| Fabcompany Limited | Health & social care | 2023 |
| Face IQ 2 Ltd | Other services | 2025 |
| Face IQ 3 Ltd | Other services | 2025 |
| Face IQ 4 Ltd | Other services | 2025 |
| Faces of the UK Limited | Other services | 2021 |
| Facile Finance Limited | Financial services | 2012 |
| Factoryroof.Com Limited | Construction | 2007 |
| Fade Theory Limited | Other services | 2025 |
| Fairbrother Pharmacy Limited | Wholesale & retail | 2003 |
| Fairbrothers Limited | Wholesale & retail | 2022 |
| Fairsource Ltd | Wholesale & retail | 2026 |
| Fairway Windows & Conservatories Ltd | Construction | 2015 |
| Fairyland Properties Ltd | Real estate | 2024 |
| Falco NOX Tech Limited | Water & waste | 2026 |
| Falcon Estates (Midlands) Limited | Real estate | 2018 |
| Falcon Outdoor Holdings Limited | Professional & scientific | 2005 |
| Falcon Outdoor Limited | Professional & scientific | 2002 |
| Falconmart Ltd | Wholesale & retail | 2025 |
| Falder Limited | Professional & scientific | 2000 |
| Falklands Management Company Limited | Households | 2000 |
| Faraday Electrical Holdings Limited | Financial services | 2020 |
| Faraday Electrical Installations Ltd. | Construction | 2004 |
| Faria Mentoring and Career Services C.I.C. | Education | 2023 |