| DAN TIM Ltd | Transport & logistics | 2016 |
| Danavas Limited | Transport & logistics | 2014 |
| Dandok Grill Restaurant Ltd | Hospitality | 2024 |
| Danecliff Limited | Real estate | 2005 |
| Danka Investments Limited | Real estate | 2018 |
| Danny Auto Drive Ltd | Education | 2026 |
| Danol Commodities Ltd | Administrative & support | 2018 |
| Danube Petroleum Limited | Mining & quarrying | 2017 |
| Danyal Sweet Centre Ltd | Hospitality | 2023 |
| Darby Chapman Limited | Construction | 2002 |
| Darby END Ltd | Hospitality | 2025 |
| Darby Holdings and Investments Ltd | Financial services | 2024 |
| Darkstar Laser Limited | Arts & recreation | 2008 |
| Darmill Tiling Limited | Construction | 2011 |
| Darren Evans Touring Ltd | Arts & recreation | 2026 |
| Dase Consulting Ltd | Real estate | 2015 |
| Dask Limited | Health & social care | 2015 |
| Data and Delivery Ltd | Information & communication | 2022 |
| Data Hall Services Group Ltd | Information & communication | 2024 |
| Data Innovations Limited | Wholesale & retail | 2012 |
| Datajaeger Limited | Professional & scientific | 2019 |
| Datalink Industrial Ltd | Manufacturing | 2026 |
| Datatec Computer Services (West Midlands) Limited | Information & communication | 1987 |
| Datatec Holdings Limited | Extraterritorial | 2024 |
| Dategrange Limited | Professional & scientific | 1989 |
| Datum Systems Holdings Ltd | Financial services | 2025 |
| Daubrey Properties Ltd | Real estate | 2024 |
| Dauntsey Guns Limited | Wholesale & retail | 2003 |
| Dave's Discount (Stores) Limited | Wholesale & retail | 2001 |
| Dave's Discount Limited | Extraterritorial | 1993 |
| Dave's Discount Stores (Kidderminster) Limited | Wholesale & retail | 2021 |
| Dave's Discount Stores (Madeley) Limited | Wholesale & retail | 2021 |
| Davian Construction Limited | Construction | 2020 |
| Davian Holdings Limited | Financial services | 2025 |
| David Brealey (Developments) Ltd | Construction | 2024 |
| David Brealey (Holdings) Ltd | Financial services | 2023 |
| David Fawkner Architectural Design Limited | Professional & scientific | 2007 |
| David Miller & SON Limited | Construction | 2011 |
| David Wignall Ltd | Real estate | 2017 |
| Davinte Holdings and Investments Ltd | Financial services | 2025 |
| Davinte Ltd | Construction | 2015 |
| Davo & Baran Ltd | Other services | 2026 |
| Davthom Limited | Construction | 2008 |
| Dawaj Limited | Administrative & support | 2023 |
| Dawar Subs Limited | Hospitality | 2014 |
| Dawn Penson Trading Ltd | Wholesale & retail | 2020 |
| Dawood Grocery Shop 247 Ltd | Wholesale & retail | 2025 |
| Dawood Grocery Shop Ltd | Wholesale & retail | 2025 |
| Daylight Care Services Ltd | Health & social care | 2022 |
| DB Components Ltd | Wholesale & retail | 2024 |
| DB Holdings and Investments Ltd | Financial services | 2024 |
| DBF Commercial Holdings Limited | Real estate | 2018 |
| DBP Design and Build Ltd | Construction | 2026 |
| DBP Maintenance Ltd | Construction | 2026 |
| DBP Optical Ltd | Health & social care | 2021 |
| Dbsr United Group Ltd | Wholesale & retail | 2022 |
| DC Building Services and Maintenance Limited | Construction | 2025 |
| DC Customs Limited | Wholesale & retail | 2015 |
| DC Grounds Maintenance (West Midlands) Ltd | Administrative & support | 2021 |
| DC Midlands Ltd | Financial services | 2023 |
| DC UK (Holdings) Ltd | Financial services | 2023 |
| Dchealthjoy Ltd | Health & social care | 2025 |
| Dcja Holdings Ltd | Financial services | 2026 |
| DDG Vehicle Services Ltd | Wholesale & retail | 2022 |
| DE Boeuf Events Ltd | Hospitality | 2025 |
| DEA Emergency Tyres Limited | Manufacturing | 2023 |
| Deamy Limited | Construction | 2025 |
| Dean Parry & Sons Limited | Construction | 2002 |
| Dean Parry Holdings Limited | Professional & scientific | 2007 |
| Debimesh Ltd | Health & social care | 2023 |
| Debjos Imports Limited | Hospitality | 2020 |
| Decolonise Architecture Ltd | Administrative & support | 2022 |
| Dedride Ltd | Wholesale & retail | 2018 |
| Deedan Group Ltd | Construction | 2019 |
| Deen and Co Property Ltd | Real estate | 2022 |
| Deen International Ltd | Extraterritorial | 2019 |
| Deen Management Associates Ltd | Professional & scientific | 2018 |
| Deep Echo Ltd | Information & communication | 2022 |
| Delight Afrocaribbean Foods Limited | Wholesale & retail | 2021 |
| Deligo Holdings Limited | Wholesale & retail | 2023 |
| Deligo Limited | Wholesale & retail | 2001 |
| Deliverics Business Solutions Limited | Professional & scientific | 2023 |
| Deliverics Limited | Professional & scientific | 2021 |
| Delta Canine Security Services Ltd | Administrative & support | 2025 |
| Delta Fire Systems Limited | Administrative & support | 1994 |
| Demca Ltd | Real estate | 2025 |
| Denison Trading Limited | Wholesale & retail | 2025 |
| Dentifi Holdings & Investments Ltd | Financial services | 2024 |
| Dentifi Ltd | Health & social care | 2024 |
| Denture Clinic (West Midlands) Limited | Health & social care | 2009 |
| Denwire Limited | Wholesale & retail | 1986 |
| Deols Limited | Transport & logistics | 2025 |
| Depolar Limited | Information & communication | 2022 |
| DES Shelley Shafts Ltd | Professional & scientific | 2020 |
| Desi PUB Ltd | Hospitality | 2023 |
| Desi Taste Dudley Limited | Hospitality | 2022 |
| Design & Integration Limited | Construction | 2004 |
| Design of Dessert Limited | Manufacturing | 2023 |
| Designers Cartel Ltd | Professional & scientific | 2013 |
| Desirable Drives and Patios 1 Ltd | Construction | 2022 |