| Ecowise Services Ltd | Wholesale & retail | 2023 |
| EDE Creative Limited | Arts & recreation | 2022 |
| Edit Property Developments Limited | Real estate | 2020 |
| EDJ Projects Ltd | Professional & scientific | 2011 |
| Edmix Construction Limited | Real estate | 1969 |
| Edridge Entertainment Ltd | Information & communication | 2025 |
| Edro Advisory Limited | Professional & scientific | 2024 |
| Education Host Ltd | Information & communication | 2015 |
| Egbert H. Taylor & Company Limited | Manufacturing | 1962 |
| Egbert Taylor Holdings Limited | Financial services | 2017 |
| EJD Consultancy Services Limited | Professional & scientific | 2021 |
| EL Digital Limited | Information & communication | 2017 |
| EL Investments & Properties Limited | Real estate | 2025 |
| Elagib Ltd | Health & social care | 2024 |
| Elaurus Developments Limited | Real estate | 2015 |
| Elaurus Holdings Limited | Financial services | 2015 |
| Elco Technical Limited | Professional & scientific | 2023 |
| Elcon Group Ltd | Construction | 2014 |
| Electdirect EV Holdings Limited | Financial services | 2016 |
| Electdirect EV Ltd | Wholesale & retail | 2021 |
| Electron Commercial Utilities Limited | Energy | 2007 |
| Eleodora Ltd | Arts & recreation | 2024 |
| Elevate Craft Ltd | Construction | 2024 |
| Eleven Ventures Trading Limited | Real estate | 2021 |
| Elfrida Property Group Ltd | Real estate | 2024 |
| Elite Marine Services Ltd | Manufacturing | 2018 |
| Elite Recovery (Midlands) Ltd | Administrative & support | 2003 |
| Elite Surgical Care Group Limited | Administrative & support | 2013 |
| Elite Surgical Healthcare Limited | Administrative & support | 2020 |
| Elite Surgical Limited | Health & social care | 2011 |
| Elizabeth Court Estates Limited | Households | 2016 |
| Ellbeeemm Consultancy Limited | Arts & recreation | 2021 |
| Elledge Informatics Limited | Information & communication | 2024 |
| Elledge Surgical Limited | Health & social care | 2022 |
| Ellora Investment Group Ltd | Financial services | 2025 |
| ELM 14 Limited | Real estate | 2017 |
| Elmbridge Farm Events Limited | Hospitality | 2018 |
| Elmgrove Construction Limited | Construction | 2020 |
| Elsinore Alliance Limited | Professional & scientific | 2015 |
| Elysium Assets Ltd | Financial services | 2015 |
| Elysium Property Assets Ltd | Real estate | 2019 |
| Embla Risk Solutions Ltd | Professional & scientific | 2026 |
| Embodied Communities CIC | Health & social care | 2022 |
| EMF Electrical & Mechanical Services Limited | Professional & scientific | 2012 |
| Emifran Limited | Other services | 2023 |
| EML Skills Limited | Professional & scientific | 2018 |
| EML Team Building Ltd | Administrative & support | 2026 |
| EMPOWER4LIFE Ltd | Professional & scientific | 2024 |
| Energy Audit Services Ltd | Professional & scientific | 2023 |
| Enertech Limited | Manufacturing | 1935 |
| Engine House Construction Limited | Real estate | 2020 |
| English Works Limited | Education | 2003 |
| Enia Clinics Ltd | Health & social care | 2026 |
| Enigma Commercial Centre F.H. Limited | Administrative & support | 2025 |
| Entouraj Restaurant Ltd | Hospitality | 2021 |
| Envestors Limited | Information & communication | 2010 |
| Environmental Nature Security Overwatch Limited | Information & communication | 2025 |
| Epadusquer Ltd | Administrative & support | 2023 |
| Ephraim Fruitful Ltd | Professional & scientific | 2022 |
| EPL Homes Ltd | Real estate | 2025 |
| Epos Online Ltd | Information & communication | 2013 |
| EQD Services Ltd | Professional & scientific | 2008 |
| Equestrian Direct Ltd | Wholesale & retail | 1997 |
| Ermi’S Sandwich Bar Limited | Hospitality | 2024 |
| Errington Enterprises Limited | Professional & scientific | 2012 |
| Esaar Limited | Health & social care | 2021 |
| Eskay Realty Limited | Real estate | 2022 |
| Esky Learning Limited | Education | 2008 |
| Esmire Property Limited | Real estate | 2022 |
| Esmire Trading Limited | Real estate | 2022 |
| ESN Properties Ltd | Real estate | 2019 |
| Essential Earth Ltd | Manufacturing | 2010 |
| Estadio Ltd | Hospitality | 2024 |
| Eterna Home Limited | Wholesale & retail | 2021 |
| ETG Civil Engineering Groundworks Ltd | Professional & scientific | 2012 |
| Etonhurst Limited | Administrative & support | 2022 |
| Ettington Properties Ltd | Real estate | 2026 |
| Eulio Studio Ltd | Professional & scientific | 2025 |
| Eurobac Environmental Limited | Water & waste | 2014 |
| Europe Touring Limited | Arts & recreation | 2009 |
| European Retail Engineering Limited | Administrative & support | 2001 |
| Evelench Court (Management) Limited | Real estate | 2006 |
| Events of Elegance Limited | Administrative & support | 2018 |
| Ever Safe First AID Limited | Education | 2023 |
| Everton House Management Company Limited | Real estate | 2014 |
| Everyone Belongs CIC | Education | 2026 |
| Everything Epos Ltd | Information & communication | 2013 |
| Evesham Chiropractic Ltd | Health & social care | 2019 |
| Evidence Based Health Ltd | Health & social care | 2015 |
| Evolved Property Holdings Ltd | Real estate | 2020 |
| Evolved Property Solutions Ltd | Real estate | 2019 |
| EWE and Lamb (Bromsgrove) Limited | Hospitality | 2007 |
| Ex-Men Exhibitions & Events Limited | Administrative & support | 2022 |
| Excalibur Barber Shop Limited | Other services | 2018 |
| Excel EDM Supplies Ltd | Professional & scientific | 2014 |
| Excel Precision (Birmingham) Ltd | Manufacturing | 1969 |
| Excel Precision (Wire Spark Erosion) Limited | Manufacturing | 1978 |
| Excel Precision Group Ltd | Administrative & support | 2010 |
| Excool Energy Ltd | Wholesale & retail | 2026 |
| Excool Holdings Limited | Administrative & support | 2019 |