| SEU Wang LE Invest Ltd | Wholesale & retail | 2020 |
| SEU WAW Invest Ltd | Extraterritorial | 2025 |
| SEU WAW Ltd | Extraterritorial | 2025 |
| SEU World Partner Invest Ltd | Wholesale & retail | 2020 |
| SEU World Partner Ltd | Extraterritorial | 2020 |
| SEU Worldwide Business Ltd | Professional & scientific | 2020 |
| SEU Yourtrainingsolution Ltd | Professional & scientific | 2016 |
| SEU ZH Cars Invest Ltd | Extraterritorial | 2012 |
| SEU ZH Cars Ltd | Extraterritorial | 2012 |
| Shahjalal Catering Ltd | Hospitality | 2025 |
| Shakespeare Court Management Limited | Extraterritorial | 1986 |
| Shakila Ltd | Other services | 2021 |
| Shakkthi Ltd | Wholesale & retail | 2019 |
| Shan Beauty Ltd Ltd | Other services | 2022 |
| Shans Barbershop Ltd | Other services | 2020 |
| Shans Nail Ltd | Other services | 2023 |
| Sharethemedia Ltd | Professional & scientific | 2023 |
| Sharp Electrics (Kent) Limited | Construction | 2025 |
| Sharps Building Services Ltd | Construction | 2026 |
| Shaun Wheels Ltd | Transport & logistics | 2025 |
| Shaw Energy Compliance Ltd | Professional & scientific | 2025 |
| Shaw Waste Limited | Water & waste | 2023 |
| Shaws Building & Roofing Ltd | Construction | 2021 |
| SHE Sells Refills, by the Seashore Ltd | Wholesale & retail | 2021 |
| Shepherd Bay Ltd | Professional & scientific | 2026 |
| Shep’S Shack Limited | Wholesale & retail | 2024 |
| Shiloh Morgan Limited | Extraterritorial | 2015 |
| Shin- Security, Service Ltd | Administrative & support | 2024 |
| Shine Cleaning Services Ltd | Administrative & support | 2022 |
| Shine Safety Systems Limited | Public administration | 2025 |
| Shipwreck Records Limited | Arts & recreation | 2010 |
| Shoreline Living Ltd | Real estate | 2026 |
| Short Straits Maritime Cluster Ltd | Information & communication | 2025 |
| Showmoves Logistics Ltd | Transport & logistics | 2025 |
| Shree Sava Ltd | Wholesale & retail | 2016 |
| Sienna Continuity Trust Ltd | Professional & scientific | 2019 |
| Sign Hub Solutions Limited | Professional & scientific | 2014 |
| Sign UP (UK) Limited | Real estate | 2006 |
| Silvercrown Investments Limited | Real estate | 1999 |
| Silverline European Trading Ltd | Wholesale & retail | 2011 |
| Simes Services Ltd | Real estate | 2025 |
| Simone Leigh Ltd | Arts & recreation | 2021 |
| Simple Life (Favourite Places) Ltd | Construction | 2015 |
| Simply Safety Limited | Professional & scientific | 2001 |
| Sine Limited | Professional & scientific | 1994 |
| Singledge Properties Ltd | Real estate | 2024 |
| Sippican Consulting LLC | | 2008 |
| Sitebridge Ltd | Information & communication | 2025 |
| Sitra (UK) Limited | Transport & logistics | 1996 |
| Siva 5 & Sons Ltd | Wholesale & retail | 2019 |
| SIX Robins Ltd | Households | 2013 |
| SJ Echotech Limited | Health & social care | 2025 |
| SJB Consultancy Services Limited | Professional & scientific | 2022 |
| SJJ Developments Ltd | Real estate | 2021 |
| SJJ Scaffolding Limited | Construction | 2014 |
| Skead Ltd | Wholesale & retail | 2023 |
| Slade Wolfe Enterprises Limited | Information & communication | 2017 |
| Sleepyhead Beds Ltd | Wholesale & retail | 2013 |
| SM Flooring Solutions Ltd | Construction | 2025 |
| Smart Ways Management Ltd | Professional & scientific | 2025 |
| Smarter and Easier Limited | Professional & scientific | 2017 |
| Smartroofsolar Ltd | Extraterritorial | 2012 |
| Smash Bar Limited | Hospitality | 2025 |
| Smashdee Ltd | Hospitality | 2026 |
| SMD Compagny Invest Ltd | Extraterritorial | 2025 |
| SMD Compagny Ltd | Extraterritorial | 2025 |
| SMD Consultancy Ltd | Professional & scientific | 2025 |
| Smiith Limited | Wholesale & retail | 2025 |
| Smok Air Ltd | Wholesale & retail | 2013 |
| Smyth Property Holdings Limited | Real estate | 2020 |
| Snack Shack Food Ltd | Hospitality | 2026 |
| Snapsymphony Limited | Professional & scientific | 2025 |
| Snuggle Feet Limited | Wholesale & retail | 2007 |
| Snuggs Medical Ltd | Administrative & support | 2023 |
| Societe Dexpansion Commerciale Invest Ltd | Professional & scientific | 2017 |
| Societe Dexpansion Commerciale Ltd | Extraterritorial | 2017 |
| Societe Gestion Services Infirmiers ET Medicaux Ltd | Professional & scientific | 2017 |
| Sofas and Things Ltd | Wholesale & retail | 2025 |
| SOFTECH360 Ltd | Information & communication | 2022 |
| Solariq Ltd | Construction | 2025 |
| Solarwatt Digital Ltd | Professional & scientific | 2023 |
| Solid Scaffolding S.E. Ltd | Construction | 2024 |
| Solton Manor Farm Ltd | Agriculture & fishing | 2020 |
| Solutions OP Ltd | Professional & scientific | 2011 |
| Sophie RAE Ltd | Health & social care | 2025 |
| South East Ecology Ltd | Professional & scientific | 2024 |
| South East Recycling Ltd | Water & waste | 2024 |
| South East Roofing (Kent) Limited | Construction | 2022 |
| South Goodwins Court (Deal) Limited | Professional & scientific | 1990 |
| South Kent Hospitality Group Ltd | Hospitality | 2024 |
| Southeast Site Management Services Limited | Construction | 2015 |
| Southern Equestrian Supplies Limited | Wholesale & retail | 2008 |
| Southern Pipe Repairs Ltd | Construction | 2013 |
| Southern Plumbing Limited | Construction | 2004 |
| Sparkle Weddings & Events Limited | Hospitality | 2024 |
| Sparrow Mediation Ltd | Professional & scientific | 2020 |
| Spectral Harvest Limited | Wholesale & retail | 2026 |
| Spectrum Safety Fire Protection Limited | Manufacturing | 2026 |
| Speditrans Limited | Transport & logistics | 1987 |
| Spencer Mills Construction Management Ltd | Construction | 2024 |