| Send IT Surrey Community Interest Company | Education | 2024 |
| Septic Wizards Limited | Administrative & support | 2021 |
| Sequoia Grove Limited | Health & social care | 2023 |
| Serhii Krystiev Ltd | Information & communication | 2024 |
| Service Weave Limited | Information & communication | 2017 |
| Seventeen Group Limited | Financial services | 1981 |
| Seventeen Holdings Limited | Professional & scientific | 2019 |
| Seymac Residents Company Limited | Households | 1991 |
| Seymour Court Residents Company Limited | Households | 2005 |
| Seymours Estate Agents (Dorking) Limited | Real estate | 2015 |
| SF Equine Limited | Agriculture & fishing | 2015 |
| SGC Communications Limited | Professional & scientific | 2011 |
| Shakespeare Consulting Ltd | Information & communication | 2024 |
| Shap 2025 Ltd | Wholesale & retail | 2025 |
| Shavian Enterprises Limited | Arts & recreation | 1972 |
| Sheep House Green Residents' Association Limited | Households | 1970 |
| Shelbourne Digital Ltd | Professional & scientific | 2022 |
| Shepherdcgi Limited | Information & communication | 2023 |
| Shepherds Farm Holdings (Surrey) Limited | Financial services | 2025 |
| Sherlock Court Residents' Company Limited | Households | 2004 |
| Shift Group Ltd | Information & communication | 2025 |
| Shiremark Barn Stables Limited | Agriculture & fishing | 2013 |
| Shuttlepac Ltd | Manufacturing | 2016 |
| Sigseis Ltd | Professional & scientific | 2026 |
| Silk Route Investment Limited | Financial services | 2009 |
| Silver Cars Limited | Transport & logistics | 2002 |
| Silver Flora Ltd | Information & communication | 2018 |
| Silverdene Properties Limited | Real estate | 2003 |
| Silvermere Catering Limited | Hospitality | 2024 |
| Silvertrees Freehold Management Limited | Households | 2019 |
| Simmons Taylor Hall Professional Services Limited | Professional & scientific | 2009 |
| Simpdataanalysis Ltd | Education | 2017 |
| Simple Quotes Limited | Information & communication | 2023 |
| Simply Performance Limited | Wholesale & retail | 2016 |
| Sipello Limited | Wholesale & retail | 2020 |
| Sitting Comfortably Limited | Manufacturing | 2014 |
| Sitting in Comfort Limited | Health & social care | 2015 |
| SJ Proptech Consultants Ltd | Information & communication | 2022 |
| Skills Haulage Ltd | Transport & logistics | 2020 |
| Skin Guru London Ltd | Other services | 2021 |
| Sky Contracting Limited | Construction | 2024 |
| Sl&M Ltd. | Financial services | 2019 |
| Slap Limited | Information & communication | 2003 |
| Slip Safety Services Limited | Administrative & support | 2017 |
| Small Rooster Ltd | Real estate | 2025 |
| Smart Buildings Jobs Ltd | Information & communication | 2023 |
| Smart Cat Productions Ltd | Information & communication | 2011 |
| Smart-E (UK) Limited | Manufacturing | 1999 |
| Smart-E Solutions Limited | Professional & scientific | 2011 |
| Smartair Electrical Ltd | Construction | 2024 |
| Smartbuilder Support Services Limited | Administrative & support | 2014 |
| Smith England Ltd | Financial services | 2013 |
| SNE Transport Ltd | Transport & logistics | 2025 |
| Social Glitch Ltd | Professional & scientific | 2024 |
| Social Llama Assistance Ltd | Professional & scientific | 2022 |
| Social Marketing Associates Limited | Professional & scientific | 2008 |
| SOFIA7446 Limited | Manufacturing | 2025 |
| Sofsy International Ltd | Wholesale & retail | 2015 |
| Soilfixer Limited | Wholesale & retail | 2025 |
| Solar Roof Installations Limited | Construction | 2010 |
| Solna Social Limited | Professional & scientific | 2026 |
| Solution Activation Limited | Professional & scientific | 2020 |
| Somerset Gardens (5-10) Estates & Management Ltd | Real estate | 2014 |
| Somerset Gardens (Meadvale) Management Limited | Households | 2014 |
| Sondes Place Mansion Management Co Ltd | Households | 2023 |
| Sondes Place Phase 1 Limited | Real estate | 2014 |
| Songs That Move Limited | Information & communication | 2024 |
| Sophic Finance Ltd | Information & communication | 2020 |
| Sophic Secretaries Ltd | Administrative & support | 2022 |
| Sophie Deeks Ltd | Health & social care | 2025 |
| Sophrosyne Holdings Ltd | Financial services | 2023 |
| Sorrel Restaurant Limited | Hospitality | 2016 |
| Sound Advice (London) Limited | Administrative & support | 2000 |
| Sound Path Solutions Ltd | Administrative & support | 2023 |
| South Downs United Limited | Arts & recreation | 2026 |
| South East Building CJE Ltd | Manufacturing | 2025 |
| South East Equine Ltd | Professional & scientific | 2020 |
| South East Forestry and Tree Services Limited | Agriculture & fishing | 2016 |
| South East Forestry Limited | Agriculture & fishing | 2002 |
| South East Surrey Schools Education Trust | Education | 2016 |
| South East Tree Surgeons Ltd | Agriculture & fishing | 2021 |
| South Gate Automation Limited | Administrative & support | 2026 |
| South London Fire Doors Ltd | Construction | 2025 |
| South Side Quarter Management Company Limited | Real estate | 1996 |
| South View Lodge Management Company Limited | Households | 1995 |
| South West London Finance Limited | Financial services | 1961 |
| Southern Provinces Property Company Limited | Real estate | 1955 |
| Southern Restorations Limited | Other services | 2004 |
| Souths Hair Limited | Other services | 2026 |
| Sowninsurrey Limited | Agriculture & fishing | 2016 |
| SP Vehicle Solutions Limited | Wholesale & retail | 2025 |
| Space Robotics Ltd | Manufacturing | 2020 |
| Spacehoppergirl Limited | Information & communication | 2003 |
| Spark Strategic Consulting Ltd | Professional & scientific | 2018 |
| Sparklegoose Ltd | Information & communication | 2024 |
| Specialised Building Solutions Ltd | Construction | 2024 |
| Specialised Electrical Solutions Ltd | Construction | 2022 |
| Specialised Heating Solutions Ltd | Construction | 2024 |
| Specialised Sports Equipment Limited | Manufacturing | 2018 |
| Specialised UK Group Ltd | Professional & scientific | 2024 |