| Ruay Unlimited Ltd | Hospitality | 2023 |
| Rugons Ltd | Real estate | 2025 |
| Rundle Estates Ltd | Real estate | 2022 |
| Ruru Creative Ltd | Professional & scientific | 2023 |
| RVS Consultancy Limited | Information & communication | 2009 |
| S & a Property Estates Ltd | Real estate | 2024 |
| S & B Brickwork Ltd | Construction | 2015 |
| S C Civils & Maintenance Limited | Construction | 2012 |
| S Gigg Haulage Ltd | Transport & logistics | 2015 |
| S M S Environmental Limited | Water & waste | 2001 |
| S Tucker Transport Ltd | Transport & logistics | 2025 |
| S&J Rental Properties Ltd | Real estate | 2025 |
| S,A,B Furniture Restoration Ltd | Other services | 2025 |
| SAB Corporate Services Limited | Administrative & support | 2015 |
| Sabali Pots Ltd | Arts & recreation | 2018 |
| Safe Bites Limited | Information & communication | 2024 |
| Saific Holdings Ltd | Real estate | 2024 |
| Saintly Trends UK Ltd | Wholesale & retail | 2025 |
| Saligo Projects Limited | Professional & scientific | 2008 |
| Salinas Cafe Ltd | Hospitality | 2012 |
| Samba Family Solutions Ltd | Real estate | 2024 |
| Samcab Transport Ltd. | Transport & logistics | 2025 |
| Samentical Limited | Construction | 2026 |
| Samla Tribe Limited | Wholesale & retail | 2014 |
| Samurai Snow Limited | Administrative & support | 2012 |
| Sandford, Hearn, Harris & Associates Ltd | Financial services | 2021 |
| SAR Infra Ltd | Information & communication | 2023 |
| Sara Amaryllis Ltd | Agriculture & fishing | 2018 |
| Sarah Roberts Inventories Ltd | Administrative & support | 2016 |
| Sarah Smith Consulting Ltd | Professional & scientific | 2016 |
| Sarthaka Limited | Information & communication | 2024 |
| Sarvaniyam Labs Ltd | Information & communication | 2025 |
| Satara Technology Ltd | Information & communication | 2025 |
| Satellite Applications Catapult Limited | Professional & scientific | 2012 |
| Satellite Applications Catapult Services Limited | Professional & scientific | 2012 |
| Satraka Ltd | Professional & scientific | 2022 |
| Satvinder & Harjinder Matharu Ltd | Real estate | 2023 |
| Sauc'D Ltd | Manufacturing | 2024 |
| Savage Estates Limited | Real estate | 2016 |
| Savages (Blewbury) Limited | Wholesale & retail | 2002 |
| Saveyu Ltd | Education | 2018 |
| SB Consulting Solutions Limited | Professional & scientific | 2019 |
| Scaleups Ventures Ltd | Professional & scientific | 2024 |
| Scheuermann-Freestone Cardiology Ltd | Health & social care | 2018 |
| Scicorp Ltd | Professional & scientific | 2024 |
| Scitech Precision Limited | Manufacturing | 2009 |
| Scorpion Signs Limited | Manufacturing | 2013 |
| Scott's Commercial Services Limited | Administrative & support | 2004 |
| SDG Works Limited | Administrative & support | 2026 |
| Seacroft Holdings Ltd | Real estate | 2024 |
| Seafield Advisory Limited | Professional & scientific | 2024 |
| Seam Projects Ltd | Professional & scientific | 2026 |
| Seamless Commerce Ltd | Wholesale & retail | 2025 |
| Seawarrior Holdings Ltd | Real estate | 2024 |
| Segavas Properties Ltd | Real estate | 2019 |
| SEN Families Unite CIC | Health & social care | 2026 |
| Send IT to Alex Ltd | Administrative & support | 2019 |
| Sequestim Limited | Administrative & support | 2016 |
| Serino Brickwork Ltd | Construction | 2019 |
| SET in Stone Didcot Ltd | Manufacturing | 2023 |
| Seven Eight Investments Ltd | Real estate | 2023 |
| Seven Principles Quality Management Limited | Professional & scientific | 2023 |
| Seventeen Market Street Commercial Ltd | Real estate | 2025 |
| Seventeen Market Street Ltd | Real estate | 2025 |
| Shadbolt Investments Ltd | Real estate | 2025 |
| Shahab Business Solutions Limited | Information & communication | 2012 |
| Shamshad Pizza Ltd | Hospitality | 2024 |
| Shanaya Properties Limited | Construction | 2024 |
| Sharp Eyes Studios Ltd | Information & communication | 2016 |
| Shayler Concrete Pumping Limited | Construction | 2002 |
| Shedder Ltd | Wholesale & retail | 2024 |
| Sherfield Flooring Limited | Construction | 1981 |
| Shojin Ventures Ltd | Real estate | 2023 |
| Shoppers Ltd | Wholesale & retail | 2025 |
| Shou BAO Limited | Financial services | 2026 |
| Shreeviswa Solutions Ltd | Information & communication | 2019 |
| Shreyat Ltd | Wholesale & retail | 2015 |
| Shrishaas Limited | Information & communication | 2018 |
| Shukla Ventures Limited | Information & communication | 2024 |
| Shumba Trading Ltd | Wholesale & retail | 2023 |
| SIB Property Ltd | Construction | 2009 |
| Sibaca Facilities Solutions Limited | Information & communication | 2024 |
| Sidesign Works Ltd | Professional & scientific | 2021 |
| Sierraindia Ltd | Real estate | 2023 |
| Signature Consult Ltd | Professional & scientific | 2011 |
| Silchester Limited | Administrative & support | 1987 |
| Silverbird Entertainment Ltd | Arts & recreation | 2011 |
| Simm Holdings Ltd | Financial services | 2021 |
| Simon and Sons Property Limited | Real estate | 2026 |
| Simvue Limited | Information & communication | 2026 |
| Singh Property Developer Limited | Real estate | 2024 |
| Singha LEO Impex Ltd | Administrative & support | 2011 |
| Sise Ltd | Information & communication | 2003 |
| Siteforge.Uk Ltd | Professional & scientific | 2024 |
| Size Entertainment Ltd | Arts & recreation | 2025 |
| SJS Installs Limited | Construction | 2015 |
| SJW Heating Ltd | Construction | 2018 |
| Skbalusu Solutions Limited | Information & communication | 2015 |
| SKF Haualge Limited | Transport & logistics | 2018 |
| Skiotis Greek Fruits Ltd | Wholesale & retail | 2025 |