| Web Hosting Guru Ltd | Information & communication | 2017 |
| Webinfusion Limited | Other services | 2006 |
| Wellington Welding Supplies Limited | Wholesale & retail | 1964 |
| West Country Homes (Torre) Limited | Wholesale & retail | 1988 |
| West Heanton Ltd | Health & social care | 2006 |
| West HOE Garage Ltd. | Wholesale & retail | 2002 |
| West Ridge Equine Limited | Professional & scientific | 2016 |
| Westacott Investments Ltd | Real estate | 2021 |
| Westcare Construction (Southwest) Limited | | 1983 |
| Westcliff Heights Limited | Households | 2004 |
| Westcountry Alarms Limited | Manufacturing | 2006 |
| Westcountry Meringues Ltd | Manufacturing | 2007 |
| Westcountry Motors Limited | Wholesale & retail | 2003 |
| Westcountry Natural Craft Limited | | 1986 |
| Westdown Farm Limited | Agriculture & fishing | 2003 |
| Western Reeds Limited | | 1988 |
| Westframe Homes Ltd | Construction | 2003 |
| Westframe Investments Limited | Construction | 1987 |
| Westpoint Centre (Devon) Limited | Arts & recreation | 1989 |
| Westward Securities (Braunton) Limited | Hospitality | 1970 |
| Westwynde Limited | Education | 2003 |
| WF & JD Slade Ltd | Construction | 2002 |
| Wheels South West Limited | | 1984 |
| Whiterock Services Limited | Other services | 2003 |
| William Speak(Farms)Limited | Agriculture & fishing | 1957 |
| Willow Chip Mushrooms LLP | | 2025 |
| Willpower Marketing Limited | | 1985 |
| Wills & Williams | | 1992 |
| Wills and Williams | | 1998 |
| Wills Marine Limited | Wholesale & retail | 1998 |
| Wilsons Paints Limited | Wholesale & retail | 2003 |
| Wilsworthy Consulting Limited | Professional & scientific | 2006 |
| Wind Runner Studios Limited | Professional & scientific | 2018 |
| Winiger-Willis Enterprises Ltd | Health & social care | 2018 |
| Winner Kane 2018 Limited | Hospitality | 2018 |
| Winners 2000 Fitness Limited | Administrative & support | 1999 |
| Winson Petroleum Limited | Wholesale & retail | 1999 |
| WNW Design Limited | Information & communication | 2003 |
| WNY Services Ltd | Transport & logistics | 2018 |
| Wood Surgery Limited | Health & social care | 2016 |
| Woodcrafts Fencing Limited | | 1970 |
| Woodforde & Co Limited | Wholesale & retail | 1996 |
| Woodland House (Plymouth) Management Limited | Real estate | 1990 |
| Woodlets Limited | Real estate | 1999 |
| Woodton Lodge Investments Limited | Real estate | 1971 |
| Woolacombe Food Store Limited | Wholesale & retail | 2003 |
| Woolloongabba Capital Ltd | Real estate | 2022 |
| Wortham Jaques Limited | Professional & scientific | 1998 |
| Wrafton Laboratories Limited | Manufacturing | 1991 |
| Wrigley Confectionery Company Limited | Manufacturing | 2005 |
| WTW - Scott Cinemas South West Limited | Information & communication | 2003 |
| Xinzo Limited | Agriculture & fishing | 2003 |
| XL Building Solutions Limited | Construction | 2004 |
| Xvat AI Ltd | Information & communication | 2025 |
| XYZ Machine Tools (Holdings) Limited | Financial services | 2024 |
| Y@ Limited | Transport & logistics | 1996 |
| Yates Transport Company (Poole) Limited | | 1985 |
| Yelverton Television Services Ltd | Other services | 2002 |
| Yeoward Boatyards Limited | Transport & logistics | 2003 |
| Yeoward Moorings Limited | Transport & logistics | 2002 |
| YGS Landscapes Limited | Administrative & support | 2006 |
| Yomi Contracting Ltd | Transport & logistics | 2017 |
| Young Devon | Other services | 1996 |
| Young Devon Trading Limited | Other services | 2016 |
| Your Face IS Your Fortune Limited | Extraterritorial | 2006 |
| Zimon Services Ltd | Transport & logistics | 2017 |
| Zincrest Limited | Wholesale & retail | 2026 |
| Zittam Ltd | Manufacturing | 2018 |