| Derry Property Resolutions Ltd | Other services | 2009 |
| Derry Rentals Ltd | Real estate | 2005 |
| Derry Vale Products Ltd | Hospitality | 2026 |
| Design IT Creative Graphic Design Limited | Professional & scientific | 2015 |
| Devine Distribution Ireland Ltd | Transport & logistics | 2019 |
| DG Fuels NI Ltd | Wholesale & retail | 2026 |
| Diamond Shelf Company Number 41 Limited | Real estate | 2014 |
| Diamond Shelf Company Number 42 Limited | Real estate | 2014 |
| Diamond Shelf Company Number 43 Limited | Real estate | 2014 |
| Digimediamanagement Limited | Professional & scientific | 2021 |
| Diorite Limited | Real estate | 2003 |
| Disfreq Limited | Arts & recreation | 2022 |
| Dispensary Limited - the | Administrative & support | 1999 |
| Dispo Products Limited | Wholesale & retail | 2012 |
| Distant Shores Developments Limited | Construction | 2021 |
| District 47 Barbering Company Limited | Other services | 2019 |
| Diver Donaghy & Company Limited | Professional & scientific | 2007 |
| DJ Kelly Construction Ltd | Construction | 2020 |
| DJM Orthopaedics Limited | Health & social care | 2025 |
| DK1 Developments Limited | Construction | 2004 |
| DL Stores (Bogside) Ltd | Wholesale & retail | 2019 |
| DL Stores Glenowen Ltd | Wholesale & retail | 2019 |
| Dldoherty Ltd | Information & communication | 2022 |
| DM GAS Plumbing & Heating Limited | Construction | 2019 |
| DML Interior Systems Ltd | Construction | 2018 |
| Docherty Bros Ltd | Construction | 2023 |
| Dog Ears Ltd | Information & communication | 2010 |
| Doherty & Co Accountants Ltd | Professional & scientific | 2024 |
| Dolipas Farms Limited | Agriculture & fishing | 2011 |
| Dolyns Limited | Financial services | 2013 |
| Donegal Glass Limited | Manufacturing | 2015 |
| Donegal Halfway Ltd | Administrative & support | 2017 |
| Donegal Properties Ltd | Real estate | 2016 |
| Donnybrewer Joinery Ltd | Construction | 2016 |
| Donnybridge Properties Ltd | Real estate | 2026 |
| Donnybrook Residential Waterside Limited | Real estate | 2005 |
| Dove House Community Trust | Education | 1996 |
| Draidancampbell Ltd | Health & social care | 2018 |
| DREAMS4LESS Limited | Arts & recreation | 2019 |
| DSE Contracts Ltd | Construction | 2021 |
| Dsol Reporting Ltd | Health & social care | 2020 |
| DTP Printing Ltd | Manufacturing | 2015 |
| DTS Plumbing&Heating Limited | Construction | 2018 |
| Duddy Hotels Limited | Financial services | 2014 |
| Duffy Excavations & Civils Limited | Construction | 2019 |
| Duffy Plant Hire & Groundworks Limited | Construction | 2014 |
| Dunfield Terrace Management Company Ltd | Financial services | 2019 |
| Dungullion Ltd | Financial services | 2025 |
| Dunroe Properties Limited | Construction | 2008 |
| DWD Enterprises Limited | Wholesale & retail | 2007 |
| E&P GEE Properties Ltd | Real estate | 2015 |
| E.H. Callaghan Limited | Health & social care | 2025 |
| Earhart Group Ltd | Wholesale & retail | 2023 |
| Easy Customs UK Limited | Administrative & support | 2020 |
| Easy Renewables Ltd | Extraterritorial | 2013 |
| EBR Events Ltd | Arts & recreation | 2025 |
| Ebrington Leisure Holdings Limited | Hospitality | 2015 |
| ECB Training & Solutions Ltd | Information & communication | 2022 |
| Eccles Electrical Limited | Construction | 2023 |
| Eccles Estates Ltd | Real estate | 2020 |
| Eccles Property Group Ltd | Hospitality | 2022 |
| Ecoride Repairs Ltd | Manufacturing | 2024 |
| EDM Ardmore Limited | Construction | 2018 |
| Eezee Estate Agents Limited | Real estate | 2022 |
| EGH (NI) Ltd | Professional & scientific | 2013 |
| EGH ES (N.I.) Limited | Energy | 2016 |
| EGH MS Limited | Wholesale & retail | 2016 |
| Eirchemicals Ltd | Administrative & support | 2016 |
| Elagh Developments (NO.1) Limited | Construction | 2025 |
| Elagh Developments Limited | Construction | 2012 |
| Elite Aesthetic Clinic Ltd | Health & social care | 2014 |
| Elmwood Enterprises (Derry) Limited | Hospitality | 2025 |
| Emagination Ltd | Professional & scientific | 2011 |
| Emera Market Trading Limited | Wholesale & retail | 2026 |
| Emerald Plant Training Ltd | Manufacturing | 2025 |
| Emeraldbridge Commerce Limited | Wholesale & retail | 2025 |
| Emerge Gym Limited | Arts & recreation | 2018 |
| Enagh Community Development Group Ltd | Administrative & support | 2025 |
| Energy Maintenance Engineering Services Ltd | Construction | 2016 |
| Ennish Construction Ltd | Construction | 2022 |
| Enquip Supplies Ltd | Wholesale & retail | 2021 |
| Epbm Developments Ltd | Construction | 2024 |
| Equine Enrichment C.I.C. | Other services | 2017 |
| ERA Music Ltd | Arts & recreation | 2019 |
| ERE Developments Limited | Energy | 2010 |
| ERE Project Management Services Limited | Professional & scientific | 2011 |
| ESB Solar (Northern Ireland) Limited | Energy | 2015 |
| Ethan Tyre Electrical Limited | Construction | 2025 |
| Euro FX NI Ltd | Wholesale & retail | 2016 |
| Events and Parties Ltd | Hospitality | 2026 |
| Extreme Partitions and Fitouts Limited | Construction | 2012 |
| F CON Ltd | Construction | 2023 |
| Factory Automation Systems Technologies Limited | Manufacturing | 2001 |
| Farren Architects Commercial Limited | Professional & scientific | 2014 |
| Farrimondmacmanus Limited | Professional & scientific | 2005 |
| Fashion & Textile Skills C.I.C. | Manufacturing | 2014 |
| Faughanvale Engineering Ltd | Extraterritorial | 2023 |
| Faughnan Financial Services Limited | Professional & scientific | 2017 |
| FC Builders Ltd | Administrative & support | 2013 |
| Fdhu Limited | Real estate | 2021 |