| Rycerz Limited | Transport & logistics | 2023 |
| Rylinz Drive Force Limited | Transport & logistics | 2004 |
| S & C Window Repairs Limited | Construction | 2012 |
| S & M Recruitment Ltd | Administrative & support | 2024 |
| S & N Contracting Ltd | Agriculture & fishing | 2021 |
| S & S Motors (Norwich) Ltd | Wholesale & retail | 2017 |
| S Christopher Services Limited | Transport & logistics | 2010 |
| S D Beesley Ltd | Transport & logistics | 2024 |
| S J Wearmouth Limited | Financial services | 2017 |
| S K Construction Limited | Construction | 2005 |
| S Willis Consultancy Limited | Information & communication | 2010 |
| S&S Motors (East) Ltd | Wholesale & retail | 2021 |
| S.A.M. Windows and Conservatories Limited | Construction | 2002 |
| S.C.W.S. (Holdings) Limited | Professional & scientific | 1966 |
| S.C.W.S. Limited | Construction | 1984 |
| Saint Capital UK Limited | Wholesale & retail | 2026 |
| Saltanat R&D Consulting Limited | Professional & scientific | 2026 |
| Salus Mortgage Solutions Ltd | Financial services | 2016 |
| Samuel Eglington (Horticulture) Ltd | Agriculture & fishing | 2009 |
| SAN Management Ltd | Administrative & support | 2019 |
| Sandons Saddlery Limited | Wholesale & retail | 2015 |
| Sanero Ltd | Manufacturing | 2024 |
| Sapphire Frills Ltd | Wholesale & retail | 2017 |
| Sausage Holdings Limited | Financial services | 2025 |
| Saxon Property Services Ltd | Construction | 2022 |
| SB25 Ltd | Information & communication | 2024 |
| Schoolhouse Digital Ltd. | Information & communication | 2010 |
| Scientific Systems Biology Limited | Professional & scientific | 2017 |
| Scribbles Pre-School Group Limited | Education | 2011 |
| SCS Accounting Solutions Limited | Professional & scientific | 2008 |
| Scuba Libre Diving Ltd | Education | 2018 |
| Scukey Ltd | Manufacturing | 2022 |
| SD Car Repairs Limited | Wholesale & retail | 2015 |
| Seamans Farms (Bintry) Limited | Agriculture & fishing | 1977 |
| Sean Mcnulty Limited | Administrative & support | 2005 |
| Seaway Maritime Limited | Professional & scientific | 2016 |
| Sedgetek Limited | Manufacturing | 2023 |
| Sekhmet Ltd | Information & communication | 2019 |
| Selbrigg Generation Limited | Energy | 2011 |
| Sell My Race Car Limited | Hospitality | 2016 |
| Sendmate Ltd | Professional & scientific | 2025 |
| Setar Limited | Energy | 2022 |
| Seven Acres Property Group Ltd | Real estate | 2023 |
| Sevenaxis Ltd | Professional & scientific | 2025 |
| SEW Shweet Ltd | Wholesale & retail | 2021 |
| SEY Catering Ltd | Hospitality | 2019 |
| SGT Solutions Limited | Administrative & support | 2009 |
| Shaftesbury Ventures Limited | Professional & scientific | 2022 |
| Shakesby Ltd. | Manufacturing | 1978 |
| Shampooches of Dereham Ltd | Other services | 2023 |
| Sharper Margins Ltd | Administrative & support | 2025 |
| Shpendi's Ltd | Wholesale & retail | 2020 |
| Shuttercraft Norfolk Ltd | Construction | 2018 |
| Silver Taxis Limited | Transport & logistics | 2014 |
| Silverbeard and Sons Ltd | Arts & recreation | 2023 |
| Simon Lewin Pigs Limited | Agriculture & fishing | 2014 |
| Simply 1 Financial Services Ltd | Financial services | 2011 |
| Simply Sofas Direct Ltd | Wholesale & retail | 2022 |
| Sirelark Group Limited | Financial services | 2017 |
| Sirelark Spice Co Limited | Extraterritorial | 2018 |
| SJC Contractors Limited | Administrative & support | 2014 |
| Sjdc Limited | Financial services | 2011 |
| SJM Operations Ltd | Wholesale & retail | 2025 |
| SJM Property Management Norfolk Ltd | Real estate | 2025 |
| SJS Pet Services Ltd | Agriculture & fishing | 2024 |
| Skbs Limited | Professional & scientific | 2005 |
| Skilton Enterprise Limited | Information & communication | 2024 |
| Skkr Shop Ltd | Wholesale & retail | 2024 |
| Sky Rocket Ecom Ltd | Wholesale & retail | 2026 |
| Skygod Solutions Ltd | Construction | 2024 |
| Slate MGT Limited | Information & communication | 2025 |
| Slingit Ltd | Construction | 2024 |
| Slipstream Group Ltd | Financial services | 2025 |
| Smart Balance Bookkeeping Ltd | Professional & scientific | 2025 |
| Smart Systems S.E. Ltd | Wholesale & retail | 2010 |
| SMB Developments Limited | Construction | 2004 |
| SMB Property Consultancy Limited | Real estate | 2011 |
| Sobriety Club Ltd | Manufacturing | 2026 |
| Software for Solutions Ltd | Information & communication | 2012 |
| Solid Foundations Consultancy Ltd | Administrative & support | 2024 |
| Solvit Recruitment Ltd | Administrative & support | 2018 |
| Soraya Recruitment Ltd | Administrative & support | 2024 |
| SOS Lawncare Ltd | Administrative & support | 2025 |
| Soulshine Healing Ltd. | Administrative & support | 2017 |
| SP Capital Management Ltd | Financial services | 2023 |
| Spalwell Property Developments Ltd | Construction | 2019 |
| SPG Wiring Ltd | Manufacturing | 2018 |
| Spicer Property Acquisitions Limited | Real estate | 2014 |
| Spinks Design & Fabrication Ltd | Professional & scientific | 2014 |
| Splendid Media Limited | Arts & recreation | 2012 |
| Spooner Commercials Limited | Manufacturing | 2019 |
| Sports Racing Series Association Ltd | Arts & recreation | 2022 |
| Springs N Things Ltd | Water & waste | 2025 |
| SRH (Anglia) Limited | Professional & scientific | 2015 |
| Srnr Limited | Wholesale & retail | 2007 |
| SS Developments & Construction Ltd | Construction | 2022 |
| SS Homes (EA) Limited | Construction | 2026 |
| ST Ives Business Park Management Company Limited | Real estate | 2015 |
| ST Ives Land Limited | Real estate | 2008 |
| ST John's House Care Limited | Health & social care | 2013 |