| Dega Jewellery Limited | Manufacturing | 2022 |
| Deighton Building Ltd | Construction | 2025 |
| Deja New Ltd | Other services | 2025 |
| DEK Properties Ltd | Real estate | 2020 |
| Dekm Limited | Professional & scientific | 2008 |
| Dekotrading Ltd | Wholesale & retail | 2026 |
| Delahay Properties Limited | Real estate | 2026 |
| Delamin Limited | Manufacturing | 1991 |
| Delaney Building Services Limited | Construction | 2002 |
| Delfi Jaison Limited | Health & social care | 2024 |
| Delhi Junction Limited | Transport & logistics | 2013 |
| Deli WA Limited | Wholesale & retail | 2025 |
| Deli-Licious Event Catering Limited | Hospitality | 2025 |
| Delivering Demand Limited | Professional & scientific | 2017 |
| Delizia Dessert Ltd | Hospitality | 2026 |
| Delizia Fast Food Ltd | Hospitality | 2018 |
| Dell UGO Maintenance Company Ltd | Administrative & support | 2021 |
| Della Estates (Scarborough) Ltd | Real estate | 2022 |
| Della Estates Ltd | Real estate | 2020 |
| Deloxy's Bars Limited | Hospitality | 2023 |
| Delphiworx Ltd | Information & communication | 2015 |
| Delta Centre Limited | Other services | 2016 |
| Delta Centre- Health Ltd | Other services | 2019 |
| Delta CNC Limited | Information & communication | 2008 |
| Delta Developments & Property Solutions Ltd | Construction | 2020 |
| Delta SIM Technologies Ltd | Information & communication | 2023 |
| Delta Swan Limited | Professional & scientific | 2014 |
| Delta Transport Solutions Ltd | Transport & logistics | 2012 |
| Delta Vehicle Deliveries Ltd | Transport & logistics | 2025 |
| DELTA22 Homes Ltd | Real estate | 2026 |
| Deltapi Consulting Ltd | Information & communication | 2024 |
| Deltech Music Limited | Information & communication | 2023 |
| Delton Group Ltd | Financial services | 2023 |
| Delton Homes Limited | Construction | 2021 |
| Deluxe Couriers Ltd Ltd | Hospitality | 2026 |
| Deluxe Venue Derby Ltd | Real estate | 2025 |
| DEM Group Property Investments Ltd | Real estate | 2025 |
| Demo Properties Holdings Ltd | Real estate | 2026 |
| Demon Car Clinic Ltd | Wholesale & retail | 2016 |
| Demon Investments Limited | Real estate | 2017 |
| Dendro Woodland Ltd | Agriculture & fishing | 2026 |
| Dengelly Limited | Households | 1991 |
| Denholm Healthcare Limited | Health & social care | 2025 |
| Dennis Property Management Limited | Real estate | 2025 |
| Dent Blanche Limited | Health & social care | 2007 |
| Dental Devices (UK) Limited | Wholesale & retail | 2008 |
| Dentisan Limited | Manufacturing | 2007 |
| Dentmaster (Derby) Limited | Wholesale & retail | 2011 |
| Denton Developments (Midlands) Limited | Construction | 2026 |
| Deol Brothers Ltd | Real estate | 2021 |
| Department Store & Co. CIC | Wholesale & retail | 2025 |
| Dept Store Ltd | Wholesale & retail | 2022 |
| Derapharm QA Services Ltd | Professional & scientific | 2016 |
| Derbion Transport Ltd | Transport & logistics | 2022 |
| Derbnb Ltd | Real estate | 2023 |
| Derbricks Ltd | Real estate | 2025 |
| Derby & Derbyshire Local Medical Committee Limited | Health & social care | 2007 |
| Derby 4X4 and Towbars Limited | Wholesale & retail | 2015 |
| Derby Accountancy Services Ltd | Professional & scientific | 2012 |
| Derby Administration and Consultancy Services Limited | Administrative & support | 2018 |
| Derby African Union C.I.C. | Arts & recreation | 2024 |
| Derby Aggregates Ltd | Transport & logistics | 2024 |
| Derby Air Conditioning Limited | Construction | 2015 |
| Derby Airport Travel Limited | Transport & logistics | 2024 |
| Derby Alloys Limited | Wholesale & retail | 2012 |
| Derby Aluminium Company Limited | Real estate | 1976 |
| Derby and Derbyshire GP Provider Board Limited | Health & social care | 2023 |
| Derby Auto Commercials Limited | Wholesale & retail | 2014 |
| Derby Auto Electrical Services Limited | Wholesale & retail | 2000 |
| Derby Auto Electrics Ltd | Wholesale & retail | 2023 |
| Derby Auto Salvage Limited | Wholesale & retail | 2014 |
| Derby Auto Services Limited | Wholesale & retail | 2018 |
| Derby Autohaus Ltd | Wholesale & retail | 2025 |
| Derby Bar Inc Limited | Wholesale & retail | 2020 |
| Derby Barber Ltd | Other services | 2026 |
| Derby Bathroom & Heating Ltd | Construction | 2017 |
| Derby BCB Ltd | Arts & recreation | 2025 |
| Derby Bearings Holdings Limited | Financial services | 2006 |
| Derby BJJ Comps Ltd | Arts & recreation | 2021 |
| Derby Blinds Ltd | Construction | 2025 |
| Derby BMX Club Limited | Arts & recreation | 2019 |
| Derby Box Company Limited | Manufacturing | 2002 |
| Derby Braid and Trimmings Limited | Wholesale & retail | 2001 |
| Derby Brewing Company Limited | Manufacturing | 2004 |
| Derby Brewing Group Limited | Financial services | 2016 |
| Derby Brickwork Limited | Construction | 2018 |
| Derby Business College Limited | Education | 2000 |
| Derby Car Breakers Limited | Wholesale & retail | 2025 |
| Derby Care Association Ltd | Other services | 2024 |
| Derby Care Plus Limited | Health & social care | 2023 |
| Derby Cars Limited | Wholesale & retail | 2017 |
| Derby Cathedral Quarter Management Co Ltd | Real estate | 2017 |
| Derby Ceilings & Drylining Ltd | Construction | 2019 |
| Derby Ceilings Projects Limited | Construction | 2023 |
| Derby Chicken & Pizza Ltd | Hospitality | 2024 |
| Derby Chickitos Ltd | Hospitality | 2023 |
| Derby City Amateur Boxing Club Ltd | Arts & recreation | 2021 |
| Derby City Apartments Ltd | Real estate | 2019 |
| Derby City Boxing Academy Community Interest Company | Arts & recreation | 2016 |
| Derby City Glass (UK) Limited | Manufacturing | 2014 |