| Croston Meadow Residents Management Company Limited | Households | 2016 |
| Crown 4 Ltd | Real estate | 2020 |
| Crown and Feathers (Spondon) Ltd | Hospitality | 2026 |
| Crown and Feathers Ltd | Hospitality | 2024 |
| Crown Cars (Derby) Limited | Transport & logistics | 2010 |
| Crown Castle Estates Limited | Real estate | 2021 |
| Crown Comfort Care Limited | Administrative & support | 2024 |
| Crown Exec Derby Travel Ltd | Transport & logistics | 2022 |
| Crown House Apartments Property Management Company Limited | Real estate | 2005 |
| Crown IT Experts Limited | Information & communication | 2024 |
| Crown Jewellers (Derby) Ltd | Wholesale & retail | 2018 |
| Crown Point Limited | Real estate | 2013 |
| Crown Windley Limited | Manufacturing | 2001 |
| Crown Windows & Conservatories (Derby) Limited | Construction | 2005 |
| Crownbridge Business Group Ltd | Professional & scientific | 2025 |
| Crowns Engineering Limited | Professional & scientific | 2023 |
| Crowshaw Holdings Limited | Construction | 2015 |
| Cruise Contractors Ltd | Manufacturing | 2024 |
| Cruise Driving School Ltd | Education | 2023 |
| Cruise Property Developments Ltd | Construction | 2021 |
| Cruisein Automotive Ltd | Wholesale & retail | 2026 |
| Crumbs & Creations Limited | Manufacturing | 2025 |
| CRW Insights Ltd | Information & communication | 2025 |
| Crystal Clear Commercial Ltd | Financial services | 2024 |
| Crystal Clear Financial Planning Limited | Financial services | 2011 |
| Crystal Clear Wills & Estate Planning Ltd | Professional & scientific | 2026 |
| Crystal Clear Window Cleaning Derby Ltd | Administrative & support | 2022 |
| Crystal Messa Ltd | Wholesale & retail | 2025 |
| Crystal Solutions@ UK Ltd | Professional & scientific | 2026 |
| Crystal Water Technologies Ltd | Water & waste | 2013 |
| CS and JS Investments Limited | Financial services | 2023 |
| CS Homes Group Ltd | Real estate | 2025 |
| CS Jacobs Estates Ltd | Real estate | 2024 |
| CS Security Solutions Ltd | Administrative & support | 2019 |
| CS Studio Limited | Other services | 2023 |
| CS Traders Ltd | Construction | 2018 |
| CSA Kebabs Limited | Financial services | 2020 |
| CSB Group Ltd | Wholesale & retail | 2025 |
| CSJ (UK) Limited | Extraterritorial | 2012 |
| CSJ Holdings Limited | Financial services | 2023 |
| Csls Finance Ltd | Professional & scientific | 2018 |
| CSM Garage Services Ltd | Wholesale & retail | 2010 |
| CSS Cleaning Services LLP | | 2025 |
| CSS Sandwich Supplies Limited | Manufacturing | 2022 |
| CSV Build and Development Ltd | Real estate | 2024 |
| CT Consulting Engineers Ltd | Professional & scientific | 2025 |
| CT Project Works Ltd | Manufacturing | 2025 |
| CT Skills (Holdings) Limited | Education | 2012 |
| CT Skills Limited | Education | 2001 |
| CT Skills Trustee Limited | Education | 2014 |
| Ctech Resolution Ltd | Information & communication | 2015 |
| Ctex (UK) Limited | Wholesale & retail | 2000 |
| CTO Consult Ltd | Information & communication | 2018 |
| CTV Trading Ltd | Real estate | 2019 |
| Cubed Coffee Limited | Other services | 2021 |
| Cubo (Birmingham) Limited | Real estate | 2021 |
| Cubo (Edinburgh) Limited | Real estate | 2022 |
| Cubo (Leeds) Limited | Real estate | 2021 |
| Cubo (Manchester) Ltd | Real estate | 2023 |
| Cubo Birmingham 2 Ltd | Real estate | 2023 |
| Cubo Carver Street Limited | Real estate | 2019 |
| Cubo Derby Limited | Real estate | 2019 |
| Cubo Digital Assets Ltd | Information & communication | 2024 |
| Cubo Glasgow Ltd | Real estate | 2023 |
| Cubo Holdings Limited | Financial services | 2019 |
| Cubo Manchester 2 Ltd | Real estate | 2023 |
| Cubo Newcastle Limited | Real estate | 2023 |
| Cubo Nottingham Limited | Real estate | 2019 |
| Cubo Reading Ltd | Real estate | 2023 |
| Cubo Soho Ltd | Real estate | 2024 |
| Cucamara Limited | Hospitality | 1999 |
| Cuco Hair Limited | Other services | 2011 |
| CUE Vision Limited | Information & communication | 2005 |
| Cueball (Derby) Limited | Arts & recreation | 2012 |
| Cuilbeg Civils Ltd | Construction | 2025 |
| Culinary Temptations Ltd | Hospitality | 2012 |
| Cullingworth Commercials and Freight Services Limited | Financial services | 1983 |
| Cullingworth Poultry Limited | Agriculture & fishing | 2022 |
| Cultivating Curiosity Ltd | Education | 2017 |
| Cultural Quarter Living Limited | Construction | 2022 |
| CULTUREV8TE Limited | Professional & scientific | 2017 |
| Cumberland Services Limited | Financial services | 2020 |
| Cunard Consulting Ltd | Information & communication | 2018 |
| Cunningham Interiors Limited | Construction | 2014 |
| Cunninghams Limited | Professional & scientific | 1993 |
| Cupitt & SON Ltd | Construction | 2023 |
| Cuppa Karak Limited | Hospitality | 2025 |
| Cura Services Limited | Information & communication | 2012 |
| Curegenix Ltd | Health & social care | 2024 |
| Curiousco Limited | Professional & scientific | 2023 |
| Curlaborate Ltd | Education | 2026 |
| Current Events Limited | Hospitality | 2014 |
| Curry Express & Sweet Centre Derby Ltd | Hospitality | 2023 |
| Curve Capital Holdings Limited | Health & social care | 2018 |
| Curve Conveyancing Solutions Limited | Professional & scientific | 2024 |
| Curzon Street Desserts Limited | Hospitality | 2025 |
| Cussins Homes (Yorks) Limited | Construction | 1977 |
| Custard People Ltd | Information & communication | 2026 |
| Custard Photography Limited | Information & communication | 2012 |
| Custel Design Ltd | Professional & scientific | 2011 |