| THE Right Blend Limited | Health & social care | 2024 |
| THE Rodrigues Group Limited | Real estate | 2017 |
| THE Root Room: Art Psychotherapy Limited | Health & social care | 2025 |
| THE Royal Crown Derby Porcelain Company Limited | Manufacturing | 2000 |
| THE Royce Furnishings Limited | Wholesale & retail | 2025 |
| THE Royce Lounge Limited | Hospitality | 2025 |
| THE Running Project Ltd | Wholesale & retail | 2024 |
| THE SA Rmap Ltd | Professional & scientific | 2024 |
| THE Sadler Gate Co (Derby) Ltd | Real estate | 2021 |
| THE Salad Palace Limited | Hospitality | 2024 |
| THE Sales Support Hub Ltd | Administrative & support | 2017 |
| THE Salon Hair & Beauty Ltd | Other services | 2012 |
| THE Sanctuary Wellness Centre and Retreats Ltd | Arts & recreation | 2025 |
| THE Sandwich and Shop Ltd | Hospitality | 2026 |
| THE Sauve Barbers Company Limited | Other services | 2025 |
| THE Schoolhouse Business Centre Ltd | Extraterritorial | 2010 |
| THE Secret Drinks Club Limited | Wholesale & retail | 2020 |
| THE Self Made AI Group Ltd | Information & communication | 2025 |
| THE Senad Group Limited | Education | 2002 |
| THE Send Dynamic C.I.C. | Education | 2023 |
| THE Shenstone & District Car Club Limited | Arts & recreation | 1994 |
| THE Shuga Room Ltd | Other services | 2020 |
| THE Simpson Corporation Ltd | Financial services | 2022 |
| THE Sitwell Arms Ltd | Hospitality | 2026 |
| THE Smart Content (Social Media) Ltd | Professional & scientific | 2020 |
| THE Smiths Shop Limited | Wholesale & retail | 2025 |
| THE Soccerstars Foundation CIC | Education | 2020 |
| THE Social Care Club Ltd | Professional & scientific | 2026 |
| THE Soft Play Group Ltd | Arts & recreation | 2019 |
| THE SOULM8S Ltd | Arts & recreation | 2020 |
| THE Specialist Lending Hub Ltd | Financial services | 2022 |
| THE Spondon GDS Partnership | | 2008 |
| THE Sporting Joint Ltd | Health & social care | 2011 |
| THE Sports Injury Clinic (Derby) Ltd | Other services | 2021 |
| THE Spottt Ltd | Hospitality | 2025 |
| THE Stables in the Coach House (Derby) Limited | Hospitality | 2017 |
| THE Staniforth Partnership Limited | Extraterritorial | 2017 |
| THE Starflower Company Limited | Professional & scientific | 2011 |
| THE Steel Doctor Limited | Construction | 2015 |
| THE Steven Gerrard Foundation | Health & social care | 2010 |
| THE Sticker Hive Limited | Manufacturing | 2026 |
| THE Stolen FIG Limited | Hospitality | 2026 |
| THE Strain Ltd | Wholesale & retail | 2022 |
| THE Strand Hair & Beauty Ltd | Other services | 2009 |
| THE Stranger Things Initiative Ltd | Hospitality | 2026 |
| THE Strawberry Salon Limited | Other services | 2024 |
| THE Studio, Nails and Beauty Limited | Other services | 2024 |
| THE Studio, Training Academy Limited | Education | 2023 |
| THE Suicide Space CIC | Other services | 2025 |
| THE Sunday Print Shop Ltd | Wholesale & retail | 2021 |
| THE Sustainable Drinks Co Ltd | Hospitality | 2026 |
| THE Sutherlands Residents Management Company Limited | Households | 2015 |
| THE Sweet Lounge Ltd | Hospitality | 2018 |
| THE System Dont Work Ltd | Wholesale & retail | 2020 |
| THE Tailored Woodshop Limited | Manufacturing | 2025 |
| THE Tax Partnership (Derby) Limited | Professional & scientific | 2003 |
| THE Tax Relief People Ltd | Professional & scientific | 2020 |
| THE Teachers Hub Ltd | Education | 2019 |
| THE Television Giant Ltd | Wholesale & retail | 2025 |
| THE Tenth Planet Film Ltd | Information & communication | 2023 |
| THE Thermal Heat Company Ltd | Construction | 2024 |
| THE Thoughtful Body Limited | Education | 2016 |
| THE Trent Rivers Trust | Professional & scientific | 2001 |
| THE Trinket Shelf Ltd | Wholesale & retail | 2025 |
| THE Tutor Centre Ltd | Education | 2023 |
| THE Tutor Service Ltd | Education | 2017 |
| THE Two Shires Management Consultancy Limited | Professional & scientific | 2021 |
| THE Tyre Master (Derby) Ltd | Wholesale & retail | 2011 |
| THE Ultimate Gift Co. Ltd. | Construction | 1998 |
| THE Value Creators Ltd | Professional & scientific | 2022 |
| THE Van Foundry Limited | Manufacturing | 2025 |
| THE Victorian Floor Company Ltd | Construction | 2020 |
| THE Views (Billinge) Management Company Limited | Households | 2015 |
| THE Village Shop (AOT) Ltd | Wholesale & retail | 2015 |
| THE Villas Care Homes Ltd | Health & social care | 2013 |
| THE Violet PUB Company Ltd | Hospitality | 2023 |
| THE Vulcan Arms Ltd | Hospitality | 2022 |
| THE Wardrobe Derby Ltd | Wholesale & retail | 2025 |
| THE Washroom Vending Association Limited | Other services | 2021 |
| THE Watch Centre Ltd | Wholesale & retail | 2017 |
| THE Water TAP Foundation | Other services | 2010 |
| THE Wayfarer Cafe Limited | Hospitality | 2016 |
| THE Wedding House (Midlands) Limited | Wholesale & retail | 2016 |
| THE Welfare Foundation | Other services | 2017 |
| THE Well-Kitchen CIC | Hospitality | 2022 |
| THE Wellington Group Limited | Construction | 2022 |
| THE West Mill Venue Limited | Hospitality | 2015 |
| THE Western Locomotive Association Limited | Other services | 1999 |
| THE White Horse Morledge Derby Limited | Hospitality | 2013 |
| THE White Swan of Ockbrook Ltd | Hospitality | 2019 |
| THE Willow Tree Group (Derby) Limited | Construction | 2025 |
| THE Woburn Orangery Limited | Hospitality | 2015 |
| THE Women's Football Academy Ltd | Arts & recreation | 2025 |
| THE Wonky Table Restaurant Limited | Hospitality | 2014 |
| THE Woods at City Fields Management Company Limited | Households | 2022 |
| THE Workshop (Derby) Ltd | Health & social care | 2017 |
| THE Worshipful Company of Poulterers Limited | Real estate | 2019 |
| THE Yellow Property POT Ltd | Real estate | 2012 |
| THE Zenith Clinic Services Limited | Health & social care | 2026 |
| THE2SAMS Ltd | Wholesale & retail | 2023 |